TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0130nMAssay Description:Inhibition of full-length HPK1 (unknown origin) assessed as inhibition constant in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition constant in presence of ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Inhibition of full-length HPK1 (unknown origin) assessed as inhibition constant in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.209nMAssay Description:Inhibition of HPK1 (1 to 346 residues) (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.391nMAssay Description:Inhibition of HPK1 (1 to 346 residues) (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.680nMAssay Description:Inhibition of HPK1 (1 to 346 residues) (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:The compound was screened in vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition constant in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition of HPK1 (1 to 346 residues) (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]U69593 from recombinant human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-U69593 from human kappa opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of HPK1 (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]U69593 from recombinant human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of HPK1 (1 to 346 residues) (unknown origin) assessed as inhibition constant by Lanthascreen binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]U69593 from recombinant human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Displacement of [3H]U69593 from recombinant human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Displacement of [3H]U69593 from recombinant human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:The compound's binding affinity against Alpha-2B adrenergic receptor from rat kidney homogenate in the presence of phentolamineChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Displacement of [3H]DPDPE from recombinant human delta-opioid receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Displacement of [3H]-DAMGO from human mu opiod receptor expressed in CHO cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair