Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of aurora CMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 332nMAssay Description:Inhibition of PKAalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 354nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 26(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 452nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 1.21E+3nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetProtein kinase C beta type(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Nerviano Medical Sciences Oncology
Curated by ChEMBL
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair