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15 similar compounds to monomer 107200

Wt: 522.8
BDBM107155
Wt: 522.8
BDBM107156
Wt: 538.8
BDBM107158
Wt: 536.9
BDBM107168
Wt: 526.9
BDBM107174
Wt: 426.8
BDBM107175
Wt: 532.9
BDBM107176
Wt: 562.9
BDBM107177
Wt: 532.9
BDBM107178
Wt: 521.9
BDBM107179
Wt: 580.9
BDBM107184
Wt: 550.9
BDBM107185
Wt: 537.9
BDBM107201
Wt: 551.9
BDBM107202

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 107155,107156,107158,107168,107174,107175,107176,107177,107178,107179,107184,107185,107201,107202   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107177
PNG
(US8592426, 26)
Show SMILES COc1ncc(cn1)C(=O)NC1(CC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Show InChI InChI=1S/C28H24ClFN6O4/c1-14-33-24(36-40-14)23-20(10-18(29)11-21(23)30)16-3-5-19-15(9-16)4-6-22(19)34-26(38)28(7-8-28)35-25(37)17-12-31-27(39-2)32-13-17/h3,5,9-13,22H,4,6-8H2,1-2H3,(H,34,38)(H,35,37)/t22-/m0/s1
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2.60n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107176
PNG
(US8592426, 25)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)c1cncnc1
Show InChI InChI=1S/C27H22ClFN6O3/c1-14-32-24(35-38-14)23-20(9-18(28)10-21(23)29)16-2-4-19-15(8-16)3-5-22(19)33-26(37)27(6-7-27)34-25(36)17-11-30-13-31-12-17/h2,4,8-13,22H,3,5-7H2,1H3,(H,33,37)(H,34,36)/t22-/m0/s1
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3.10n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107178
PNG
(US8592426, 27)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccnnc1
Show InChI InChI=1S/C27H22ClFN6O3/c1-14-32-24(35-38-14)23-20(11-18(28)12-21(23)29)16-2-4-19-15(10-16)3-5-22(19)33-26(37)27(7-8-27)34-25(36)17-6-9-30-31-13-17/h2,4,6,9-13,22H,3,5,7-8H2,1H3,(H,33,37)(H,34,36)/t22-/m0/s1
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3.60n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107179
PNG
(US8592426, 28)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccno1
Show InChI InChI=1S/C26H21ClFN5O4/c1-13-30-23(33-36-13)22-18(11-16(27)12-19(22)28)15-2-4-17-14(10-15)3-5-20(17)31-25(35)26(7-8-26)32-24(34)21-6-9-29-37-21/h2,4,6,9-12,20H,3,5,7-8H2,1H3,(H,31,35)(H,32,34)/t20-/m0/s1
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4.10n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107168
PNG
(US8592426, 17)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2c(CCC2(C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c1
Show InChI InChI=1S/C25H21ClF4N4O3/c1-12-31-20(34-37-12)19-16(10-15(26)11-18(19)27)13-3-4-17-14(9-13)5-6-23(17,2)32-21(35)24(7-8-24)33-22(36)25(28,29)30/h3-4,9-11H,5-8H2,1-2H3,(H,32,35)(H,33,36)
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5.90n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107156
PNG
(US8592426, 5)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF4N4O3/c1-11-30-20(33-36-11)19-16(9-14(25)10-17(19)26)13-2-4-15-12(8-13)3-5-18(15)31-21(34)23(6-7-23)32-22(35)24(27,28)29/h2,4,8-10,18H,3,5-7H2,1H3,(H,31,34)(H,32,35)/t18-/m0/s1
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6.20n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107201
PNG
(US8592426, 51)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)c1ccno1
Show InChI InChI=1S/C26H21ClFN5O5/c1-13-30-23(33-37-13)22-18(9-16(27)10-19(22)28)15-2-4-17-14(8-15)3-5-20(17)31-25(35)26(11-36-12-26)32-24(34)21-6-7-29-38-21/h2,4,6-10,20H,3,5,11-12H2,1H3,(H,31,35)(H,32,34)/t20-/m0/s1
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11.8n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107185
PNG
(US8592426, 34)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)c3ccnnc3)c2c(F)c1
Show InChI InChI=1S/C27H21ClF2N6O3/c1-13-33-24(36-39-13)23-18(10-17(28)11-20(23)30)16-8-14-2-3-21(22(14)19(29)9-16)34-26(38)27(5-6-27)35-25(37)15-4-7-31-32-12-15/h4,7-12,21H,2-3,5-6H2,1H3,(H,34,38)(H,35,37)
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15.1n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107184
PNG
(US8592426, 33)
Show SMILES COc1ncc(cn1)C(=O)NC1(CC1)C(=O)NC1CCc2cc(cc(F)c12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Show InChI InChI=1S/C28H23ClF2N6O4/c1-13-34-24(37-41-13)23-18(9-17(29)10-20(23)31)15-7-14-3-4-21(22(14)19(30)8-15)35-26(39)28(5-6-28)36-25(38)16-11-32-27(40-2)33-12-16/h7-12,21H,3-6H2,1-2H3,(H,35,39)(H,36,38)
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18.9n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107155
PNG
(US8592426, 4)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF4N4O3/c1-11-30-20(33-36-11)19-16(9-14(25)10-17(19)26)13-2-4-15-12(8-13)3-5-18(15)31-21(34)23(6-7-23)32-22(35)24(27,28)29/h2,4,8-10,18H,3,5-7H2,1H3,(H,31,34)(H,32,35)
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20.2n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107202
PNG
(US8592426, 52)
Show SMILES Cc1cc(on1)C(=O)NC1(COC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Show InChI InChI=1S/C27H23ClFN5O5/c1-13-7-22(39-33-13)25(35)32-27(11-37-12-27)26(36)31-21-6-4-15-8-16(3-5-18(15)21)19-9-17(28)10-20(29)23(19)24-30-14(2)38-34-24/h3,5,7-10,21H,4,6,11-12H2,1-2H3,(H,31,36)(H,32,35)/t21-/m0/s1
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25.7n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107175
PNG
(US8592426, 24)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(N)CC1
Show InChI InChI=1S/C22H20ClFN4O2/c1-11-26-20(28-30-11)19-16(9-14(23)10-17(19)24)13-2-4-15-12(8-13)3-5-18(15)27-21(29)22(25)6-7-22/h2,4,8-10,18H,3,5-7,25H2,1H3,(H,27,29)/t18-/m0/s1
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36.4n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107158
PNG
(US8592426, 7)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF4N4O4/c1-11-30-20(33-37-11)19-16(7-14(25)8-17(19)26)13-2-4-15-12(6-13)3-5-18(15)31-21(34)23(9-36-10-23)32-22(35)24(27,28)29/h2,4,6-8,18H,3,5,9-10H2,1H3,(H,31,34)(H,32,35)/t18-/m0/s1
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37.4n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107174
PNG
(US8592426, 23)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C27H28ClFN4O4/c1-14-30-23(33-37-14)22-19(12-17(28)13-20(22)29)16-5-7-18-15(11-16)6-8-21(18)31-24(34)27(9-10-27)32-25(35)36-26(2,3)4/h5,7,11-13,21H,6,8-10H2,1-4H3,(H,31,34)(H,32,35)/t21-/m0/s1
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669n/an/an/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Binding assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107158
PNG
(US8592426, 7)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF4N4O4/c1-11-30-20(33-37-11)19-16(7-14(25)8-17(19)26)13-2-4-15-12(6-13)3-5-18(15)31-21(34)23(9-36-10-23)32-22(35)24(27,28)29/h2,4,6-8,18H,3,5,9-10H2,1H3,(H,31,34)(H,32,35)/t18-/m0/s1
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n/an/a 28.6n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107168
PNG
(US8592426, 17)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2c(CCC2(C)NC(=O)C2(CC2)NC(=O)C(F)(F)F)c1
Show InChI InChI=1S/C25H21ClF4N4O3/c1-12-31-20(34-37-12)19-16(10-15(26)11-18(19)27)13-3-4-17-14(9-13)5-6-23(17,2)32-21(35)24(7-8-24)33-22(36)25(28,29)30/h3-4,9-11H,5-8H2,1-2H3,(H,32,35)(H,33,36)
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n/an/a 0.600n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107174
PNG
(US8592426, 23)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C27H28ClFN4O4/c1-14-30-23(33-37-14)22-19(12-17(28)13-20(22)29)16-5-7-18-15(11-16)6-8-21(18)31-24(34)27(9-10-27)32-25(35)36-26(2,3)4/h5,7,11-13,21H,6,8-10H2,1-4H3,(H,31,34)(H,32,35)/t21-/m0/s1
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n/an/a 332n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107176
PNG
(US8592426, 25)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)c1cncnc1
Show InChI InChI=1S/C27H22ClFN6O3/c1-14-32-24(35-38-14)23-20(9-18(28)10-21(23)29)16-2-4-19-15(8-16)3-5-22(19)33-26(37)27(6-7-27)34-25(36)17-11-30-13-31-12-17/h2,4,8-13,22H,3,5-7H2,1H3,(H,33,37)(H,34,36)/t22-/m0/s1
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n/an/a 0.100n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107177
PNG
(US8592426, 26)
Show SMILES COc1ncc(cn1)C(=O)NC1(CC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Show InChI InChI=1S/C28H24ClFN6O4/c1-14-33-24(36-40-14)23-20(10-18(29)11-21(23)30)16-3-5-19-15(9-16)4-6-22(19)34-26(38)28(7-8-28)35-25(37)17-12-31-27(39-2)32-13-17/h3,5,9-13,22H,4,6-8H2,1-2H3,(H,34,38)(H,35,37)/t22-/m0/s1
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n/an/a 0.200n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107178
PNG
(US8592426, 27)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccnnc1
Show InChI InChI=1S/C27H22ClFN6O3/c1-14-32-24(35-38-14)23-20(11-18(28)12-21(23)29)16-2-4-19-15(10-16)3-5-22(19)33-26(37)27(7-8-27)34-25(36)17-6-9-30-31-13-17/h2,4,6,9-13,22H,3,5,7-8H2,1H3,(H,33,37)(H,34,36)/t22-/m0/s1
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n/an/a 0.400n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107179
PNG
(US8592426, 28)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccno1
Show InChI InChI=1S/C26H21ClFN5O4/c1-13-30-23(33-36-13)22-18(11-16(27)12-19(22)28)15-2-4-17-14(10-15)3-5-20(17)31-25(35)26(7-8-26)32-24(34)21-6-9-29-37-21/h2,4,6,9-12,20H,3,5,7-8H2,1H3,(H,31,35)(H,32,34)/t20-/m0/s1
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n/an/a 0.300n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107184
PNG
(US8592426, 33)
Show SMILES COc1ncc(cn1)C(=O)NC1(CC1)C(=O)NC1CCc2cc(cc(F)c12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Show InChI InChI=1S/C28H23ClF2N6O4/c1-13-34-24(37-41-13)23-18(9-17(29)10-20(23)31)15-7-14-3-4-21(22(14)19(30)8-15)35-26(39)28(5-6-28)36-25(38)16-11-32-27(40-2)33-12-16/h7-12,21H,3-6H2,1-2H3,(H,35,39)(H,36,38)
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Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107185
PNG
(US8592426, 34)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1cc2CCC(NC(=O)C3(CC3)NC(=O)c3ccnnc3)c2c(F)c1
Show InChI InChI=1S/C27H21ClF2N6O3/c1-13-33-24(36-39-13)23-18(10-17(28)11-20(23)30)16-8-14-2-3-21(22(14)19(29)9-16)34-26(38)27(5-6-27)35-25(37)15-4-7-31-32-12-15/h4,7-12,21H,2-3,5-6H2,1H3,(H,34,38)(H,35,37)
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n/an/a 0.600n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107201
PNG
(US8592426, 51)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)c1ccno1
Show InChI InChI=1S/C26H21ClFN5O5/c1-13-30-23(33-37-13)22-18(9-16(27)10-19(22)28)15-2-4-17-14(8-15)3-5-20(17)31-25(35)26(11-36-12-26)32-24(34)21-6-7-29-38-21/h2,4,6-10,20H,3,5,11-12H2,1H3,(H,31,35)(H,32,34)/t20-/m0/s1
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n/an/a 2.70n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107156
PNG
(US8592426, 5)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF4N4O3/c1-11-30-20(33-36-11)19-16(9-14(25)10-17(19)26)13-2-4-15-12(8-13)3-5-18(15)31-21(34)23(6-7-23)32-22(35)24(27,28)29/h2,4,8-10,18H,3,5-7H2,1H3,(H,31,34)(H,32,35)/t18-/m0/s1
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n/an/a 0.600n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107155
PNG
(US8592426, 4)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F
Show InChI InChI=1S/C24H19ClF4N4O3/c1-11-30-20(33-36-11)19-16(9-14(25)10-17(19)26)13-2-4-15-12(8-13)3-5-18(15)31-21(34)23(6-7-23)32-22(35)24(27,28)29/h2,4,8-10,18H,3,5-7H2,1H3,(H,31,34)(H,32,35)
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n/an/a 2n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107202
PNG
(US8592426, 52)
Show SMILES Cc1cc(on1)C(=O)NC1(COC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1
Show InChI InChI=1S/C27H23ClFN5O5/c1-13-7-22(39-33-13)25(35)32-27(11-37-12-27)26(36)31-21-6-4-15-8-16(3-5-18(15)21)19-9-17(28)10-20(29)23(19)24-30-14(2)38-34-24/h3,5,7-10,21H,4,6,11-12H2,1-2H3,(H,31,36)(H,32,35)/t21-/m0/s1
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Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair
Bradykinin-1 Receptor


(Homo sapiens (Human))
BDBM107175
PNG
(US8592426, 24)
Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(N)CC1
Show InChI InChI=1S/C22H20ClFN4O2/c1-11-26-20(28-30-11)19-16(9-14(23)10-17(19)24)13-2-4-15-12(8-13)3-5-18(15)27-21(29)22(25)6-7-22/h2,4,8-10,18H,3,5-7,25H2,1H3,(H,27,29)/t18-/m0/s1
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n/an/a 5n/an/an/an/an/an/a



Hoffmann—La Roche Inc.

US Patent


Assay Description
Calcium mobilization assay using Bradykinin-1 receptor.


US Patent US8592426 (2013)

More data for this
Ligand-Target Pair