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1 similar compounds to monomer 11889

Compile data set for download or QSAR
Wt: 307.3
BDBM11888

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11888   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Collagenase


(Homo sapiens (Human))
BDBM11888
PNG
(N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide |...)
Show SMILES ONC(=O)CS(=O)(=O)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C14H13NO5S/c16-14(15-17)10-21(18,19)13-8-6-12(7-9-13)20-11-4-2-1-3-5-11/h1-9,17H,10H2,(H,15,16)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2.60n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...


J Med Chem 48: 6713-30 (2005)


Article DOI: 10.1021/jm0500875
BindingDB Entry DOI: 10.7270/Q2N58JMZ
More data for this
Ligand-Target Pair
Collagenase


(Homo sapiens (Human))
BDBM11888
PNG
(N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide |...)
Show SMILES ONC(=O)CS(=O)(=O)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C14H13NO5S/c16-14(15-17)10-21(18,19)13-8-6-12(7-9-13)20-11-4-2-1-3-5-11/h1-9,17H,10H2,(H,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5.10n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...


J Med Chem 48: 6713-30 (2005)


Article DOI: 10.1021/jm0500875
BindingDB Entry DOI: 10.7270/Q2N58JMZ
More data for this
Ligand-Target Pair
Matrix metalloproteinase-1 (MMP1)


(Homo sapiens (Human))
BDBM11888
PNG
(N-Hydroxy-2-[(4-phenoxyphenyl)sulfonyl]acetamide |...)
Show SMILES ONC(=O)CS(=O)(=O)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C14H13NO5S/c16-14(15-17)10-21(18,19)13-8-6-12(7-9-13)20-11-4-2-1-3-5-11/h1-9,17H,10H2,(H,15,16)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
6.60E+3n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...


J Med Chem 48: 6713-30 (2005)


Article DOI: 10.1021/jm0500875
BindingDB Entry DOI: 10.7270/Q2N58JMZ
More data for this
Ligand-Target Pair