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2 similar compounds to monomer 121448

Compile data set for download or QSAR
Wt: 311.3
BDBM121446
Wt: 311.3
BDBM121449

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 121446,121449   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM121449
PNG
(US8722709, 53)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1ccnc(NC(N)=O)c1
Show InChI InChI=1S/C16H14FN5O/c1-22-9-20-14(15(22)10-2-4-12(17)5-3-10)11-6-7-19-13(8-11)21-16(18)23/h2-9H,1H3,(H3,18,19,21,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.40E+3n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM121446
PNG
(US8722709, 50)
Show SMILES Cn1cnc(c1-c1ccnc(NC(N)=O)c1)-c1ccc(F)cc1
Show InChI InChI=1S/C16H14FN5O/c1-22-9-20-14(10-2-4-12(17)5-3-10)15(22)11-6-7-19-13(8-11)21-16(18)23/h2-9H,1H3,(H3,18,19,21,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 130n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...


US Patent US8722709 (2014)


BindingDB Entry DOI: 10.7270/Q2NS0SJ4
More data for this
Ligand-Target Pair