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5 similar compounds to monomer 123687

Compile data set for download or QSAR
Wt: 274.3
BDBM123688
Wt: 284.3
BDBM123689
Wt: 286.3
BDBM123690
Wt: 288.3
BDBM123691
Wt: 300.3
BDBM123686

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 123688,123689,123690,123691,123686   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 9A


(Homo sapiens (human))
BDBM123686
PNG
(US8741907, 1)
Show SMILES O=c1[nH]c(CC2CCCCC2)nc2n(ncc12)C1CCCC1
Show InChI InChI=1S/C17H24N4O/c22-17-14-11-18-21(13-8-4-5-9-13)16(14)19-15(20-17)10-12-6-2-1-3-7-12/h11-13H,1-10H2,(H,19,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (human))
BDBM123688
PNG
(US8741907, 4)
Show SMILES CCC(C)Cc1nc2n(ncc2c(=O)[nH]1)C1CCCC1
Show InChI InChI=1S/C15H22N4O/c1-3-10(2)8-13-17-14-12(15(20)18-13)9-16-19(14)11-6-4-5-7-11/h9-11H,3-8H2,1-2H3,(H,17,18,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (human))
BDBM123691
PNG
(US8741907, 17)
Show SMILES O=c1[nH]c(CC2CCCO2)nc2n(ncc12)C1CCCC1
Show InChI InChI=1S/C15H20N4O2/c20-15-12-9-16-19(10-4-1-2-5-10)14(12)17-13(18-15)8-11-6-3-7-21-11/h9-11H,1-8H2,(H,17,18,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 86n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (human))
BDBM123690
PNG
(US8741907, 12)
Show SMILES CCC(CC)n1ncc2c1nc(CC1CCC=C1)[nH]c2=O
Show InChI InChI=1S/C16H22N4O/c1-3-12(4-2)20-15-13(10-17-20)16(21)19-14(18-15)9-11-7-5-6-8-11/h5,7,10-12H,3-4,6,8-9H2,1-2H3,(H,18,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 65n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (human))
BDBM123689
PNG
(US8741907, 6)
Show SMILES O=c1[nH]c(CC2CCC=C2)nc2n(ncc12)C1CCCC1
Show InChI InChI=1S/C16H20N4O/c21-16-13-10-17-20(12-7-3-4-8-12)15(13)18-14(19-16)9-11-5-1-2-6-11/h1,5,10-12H,2-4,6-9H2,(H,18,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. 2 uL portions of the diluted substa...


US Patent US8741907 (2014)


BindingDB Entry DOI: 10.7270/Q21V5CNH
More data for this
Ligand-Target Pair