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2 similar compounds to monomer 139215

Wt: 421.3
BDBM139210
Wt: 435.4
BDBM139213

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139210,139213   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 1 (S1P1)


(Homo sapiens (Human))
BDBM139210
PNG
(US8889668, I60)
Show SMILES COc1ccc(F)cc1-c1noc(n1)-c1ccc(N2CCCCC2)c(c1)C(F)(F)F
Show InChI InChI=1S/C21H19F4N3O2/c1-29-18-8-6-14(22)12-15(18)19-26-20(30-27-19)13-5-7-17(16(11-13)21(23,24)25)28-9-3-2-4-10-28/h5-8,11-12H,2-4,9-10H2,1H3
PDB

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KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
1n/an/an/an/an/an/an/an/a



Merck Serono SA

US Patent


Assay Description
Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells wer...


US Patent US8889668 (2014)

More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (S1P1)


(Homo sapiens (Human))
BDBM139213
PNG
(US8889668, I63)
Show SMILES COc1ccc(F)cc1-c1noc(n1)-c1ccc(N2CCCCC2C)c(c1)C(F)(F)F
Show InChI InChI=1/C22H21F4N3O2/c1-13-5-3-4-10-29(13)18-8-6-14(11-17(18)22(24,25)26)21-27-20(28-31-21)16-12-15(23)7-9-19(16)30-2/h6-9,11-13H,3-5,10H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
3n/an/an/an/an/an/an/an/a



Merck Serono SA

US Patent


Assay Description
Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells wer...


US Patent US8889668 (2014)

More data for this
Ligand-Target Pair