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4 similar compounds to monomer 50155537

Compile data set for download or QSAR
Wt: 97.9
BDBM14671
Wt: 136.0
BDBM50004328
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Wt: 95.9
BDBM50080995
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Wt: 96.9
BDBM50155534

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 14671,50004328,50080995,50155534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 4


(Homo sapiens (Human))
BDBM50080995
PNG
(CHEMBL1060 | Dibasic sodium phosphate | Disodium p...)
Show SMILES OP([O-])([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2
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Article
PubMed
9.80E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV


Bioorg Med Chem Lett 14: 5763-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.064
BindingDB Entry DOI: 10.7270/Q2V40TPN
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50155534
PNG
(CHEMBL1368 | NaH2PO4 | monosodium phosphate | phos...)
Show SMILES OP(O)([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
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PubMed
3.06E+6n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA II


Bioorg Med Chem Lett 14: 5763-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.064
BindingDB Entry DOI: 10.7270/Q2V40TPN
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50080995
PNG
(CHEMBL1060 | Dibasic sodium phosphate | Disodium p...)
Show SMILES OP([O-])([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2
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PubMed
3.67E+6n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX


Bioorg Med Chem Lett 14: 5763-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.064
BindingDB Entry DOI: 10.7270/Q2V40TPN
More data for this
Ligand-Target Pair
Ornithine carbamoyltransferase


(Homo sapiens (Human))
BDBM14671
PNG
(Fragment 1 | Phosphate | phosphoric acid)
Show SMILES OP(O)(O)=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
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6.00E+6n/an/an/an/an/an/a8.0n/a



Universit£tstrasse 16

Curated by ChEMBL


Assay Description
Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ...


J Med Chem 42: 2633-40 (1999)


Article DOI: 10.1021/jm991008q
BindingDB Entry DOI: 10.7270/Q2NV9JX8
More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (Human))
BDBM50155534
PNG
(CHEMBL1368 | NaH2PO4 | monosodium phosphate | phos...)
Show SMILES OP(O)([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
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7.57E+6n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV


Bioorg Med Chem Lett 14: 5763-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.064
BindingDB Entry DOI: 10.7270/Q2V40TPN
More data for this
Ligand-Target Pair
Ornithine carbamoyltransferase


(Homo sapiens (Human))
BDBM14671
PNG
(Fragment 1 | Phosphate | phosphoric acid)
Show SMILES OP(O)(O)=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
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1.20E+7n/an/an/an/an/an/a7.0n/a



Universit£tstrasse 16

Curated by ChEMBL


Assay Description
Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ...


J Med Chem 42: 2633-40 (1999)


Article DOI: 10.1021/jm991008q
BindingDB Entry DOI: 10.7270/Q2NV9JX8
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50080995
PNG
(CHEMBL1060 | Dibasic sodium phosphate | Disodium p...)
Show SMILES OP([O-])([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2
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Article
PubMed
1.32E+7n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA II


Bioorg Med Chem Lett 14: 5763-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.064
BindingDB Entry DOI: 10.7270/Q2V40TPN
More data for this
Ligand-Target Pair
Ornithine carbamoyltransferase


(Homo sapiens (Human))
BDBM14671
PNG
(Fragment 1 | Phosphate | phosphoric acid)
Show SMILES OP(O)(O)=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
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>2.00E+7n/an/an/an/an/an/a6.0n/a



Universit£tstrasse 16

Curated by ChEMBL


Assay Description
Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m...


J Med Chem 42: 2633-40 (1999)


Article DOI: 10.1021/jm991008q
BindingDB Entry DOI: 10.7270/Q2NV9JX8
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50155534
PNG
(CHEMBL1368 | NaH2PO4 | monosodium phosphate | phos...)
Show SMILES OP(O)([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
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PubMed
2.11E+7n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX


Bioorg Med Chem Lett 14: 5763-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.064
BindingDB Entry DOI: 10.7270/Q2V40TPN
More data for this
Ligand-Target Pair
Ketopantoate reductase


(Escherichia coli (strain K12))
BDBM14671
PNG
(Fragment 1 | Phosphate | phosphoric acid)
Show SMILES OP(O)(O)=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
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2.70E+7n/an/an/an/an/an/an/an/a



University Chemical Laboratory

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli KPR


J Med Chem 49: 4992-5000 (2006)


Article DOI: 10.1021/jm060490r
BindingDB Entry DOI: 10.7270/Q28S4QQN
More data for this
Ligand-Target Pair
phosphatase Cdc25


(Homo sapiens (Human))
BDBM50080995
PNG
(CHEMBL1060 | Dibasic sodium phosphate | Disodium p...)
Show SMILES OP([O-])([O-])=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2
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n/an/a 1.00E+7n/an/an/an/an/an/a



Mitotix, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against human Cell division cycle 25A


Bioorg Med Chem Lett 9: 2537-8 (1999)


Article DOI: 10.1016/s0960-894x(99)00431-x
BindingDB Entry DOI: 10.7270/Q2QN660F
More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase


(Bos taurus (Cattle))
BDBM50004328
PNG
(CHEBI:63036 | POTASSIUM PHOSPHATE, MONOBASIC)
Show SMILES [K+].OP(O)([O-])=O
Show InChI InChI=1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1
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n/an/a 4.32E+3n/an/an/an/an/an/a



Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.

Curated by ChEMBL


Assay Description
Inhibition of calf intestinal alkaline phosphatase using p-NPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 m...


Bioorg Med Chem 26: 3707-3715 (2018)

More data for this
Ligand-Target Pair
Intestinal alkaline phosphatase (IAP)


(Bos taurus (Cattle))
BDBM50004328
PNG
(CHEBI:63036 | POTASSIUM PHOSPHATE, MONOBASIC)
Show SMILES [K+].OP(O)([O-])=O
Show InChI InChI=1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1
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n/an/a 2.41E+3n/an/an/an/an/an/a



Quaid-i-Azam University

Curated by ChEMBL


Assay Description
Inhibition of calf intestinal alkaline phosphatase using p-nitrophenyl phosphate as substrate preincubated for 10 mins before substrate addition afte...


Eur J Med Chem 78: 167-77 (2014)


Article DOI: 10.1016/j.ejmech.2014.03.046
BindingDB Entry DOI: 10.7270/Q2F76F32
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (aa 145-252)


(Homo sapiens (Human))
BDBM14671
PNG
(Fragment 1 | Phosphate | phosphoric acid)
Show SMILES OP(O)(O)=O
Show InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)
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Article
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n/an/a>4.00E+7n/an/an/an/a7.422



Aventis Pharma



Assay Description
SPA uses 125I as energy donor and scintillant-coated beads as energy acceptor. The labeled ligand is captured by the biotinylated Src-SH2 protein imm...


J Med Chem 46: 5184-95 (2003)


Article DOI: 10.1021/jm020970s
BindingDB Entry DOI: 10.7270/Q2XW4H14
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)