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12 molecules are shown

Wt: 339.3
BDBM14754
Purchase
Wt: 371.4
BDBM50351890
Wt: 415.4
BDBM50351891
Wt: 309.3
BDBM50351892
Wt: 371.4
BDBM50351894
Wt: 403.4
BDBM50351898
Wt: 357.4
BDBM50351899
Wt: 355.4
BDBM50351900
Wt: 403.4
BDBM50351901
Wt: 371.4
BDBM50351903
Wt: 359.3
BDBM50351906
Wt: 359.3
BDBM50351908

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 53 hits for monomerid = 14754,50351890,50351891,50351892,50351894,50351898,50351899,50351900,50351901,50351903,50351906,50351908   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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0.00000800n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of rat lung cAMP-phosphodiesterase


J Med Chem 23: 1188-98 (1980)


Article DOI: 10.1021/jm00185a008
More data for this
Ligand-Target Pair
Phosphodiesterase Type 10 (PDE10A)


(Rattus norvegicus (rat))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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17 -10.5n/an/an/an/an/a7.522



Pfizer



Assay Description
PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...


J Med Chem 50: 182-5 (2007)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2930RDX
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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279n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...


J Med Chem 50: 182-5 (2007)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2930RDX
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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417n/an/an/an/an/an/an/an/a



Pfizer



Assay Description
PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...


J Med Chem 50: 182-5 (2007)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2930RDX
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(RAT)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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8.82E+3n/an/an/an/an/an/an/an/a



University of Tennessee

Curated by PDSP Ki Database




J Pharmacol Exp Ther 305: 565-72 (2003)


Article DOI: 10.1124/jpet.102.47407
BindingDB Entry DOI: 10.7270/Q23B5XQG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phosphodiesterase 4


(RAT)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



University of Tennessee

Curated by PDSP Ki Database




J Pharmacol Exp Ther 305: 565-72 (2003)


Article DOI: 10.1124/jpet.102.47407
BindingDB Entry DOI: 10.7270/Q23B5XQG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phosphodiesterase 1


(Homo sapiens (Human)-Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 2.16E+4n/an/an/an/an/an/a



Eisai Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [Ca(2+)]-calmodulin-dependent cGMP-phosphodiesterase 1 from porcine coronary arteries


J Med Chem 36: 3765-70 (1994)


Article DOI: 10.1021/jm00076a003
BindingDB Entry DOI: 10.7270/Q279459H
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 8.80E+3n/an/an/an/an/an/a



Eisai Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against cyclic GMP-phosphodiesterase (PDE V) isolated from porcine aorta.


J Med Chem 36: 3765-70 (1994)


Article DOI: 10.1021/jm00076a003
BindingDB Entry DOI: 10.7270/Q279459H
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 36n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of PDE10A (unknown origin)


Bioorg Med Chem 22: 2648-54 (2014)


Article DOI: 10.1016/j.bmc.2014.03.028
BindingDB Entry DOI: 10.7270/Q26M38C2
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 76n/an/an/an/an/an/a



Biotie Therapies GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...


J Med Chem 53: 4399-411 (2010)


Article DOI: 10.1021/jm1002793
BindingDB Entry DOI: 10.7270/Q2MK6D3N
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 36n/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to PDE10A (unknown origin)


Citation and Details

Article DOI: 10.1016/j.bmcl.2014.12.054
BindingDB Entry DOI: 10.7270/Q2H41T6N
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 76n/an/an/an/an/an/a



Biotie Therapies GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...


J Med Chem 53: 4399-411 (2010)


Article DOI: 10.1021/jm1002793
BindingDB Entry DOI: 10.7270/Q2MK6D3N
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 17n/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assay


Bioorg Med Chem 19: 642-9 (2011)


Article DOI: 10.1016/j.bmc.2010.10.038
BindingDB Entry DOI: 10.7270/Q2TT4R73
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 210n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of PDE10A


Bioorg Med Chem Lett 21: 3738-42 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.067
BindingDB Entry DOI: 10.7270/Q24B31PT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50351890
PNG
(CHEMBL1821787)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OCCF
Show InChI InChI=1S/C21H22FNO4/c1-24-18-5-4-14(11-21(18)27-9-7-22)10-17-16-13-20(26-3)19(25-2)12-15(16)6-8-23-17/h4-6,8,11-13H,7,9-10H2,1-3H3
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n/an/a 2.51E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50351891
PNG
(CHEMBL1821790)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCOCCF
Show InChI InChI=1S/C23H26FNO5/c1-26-21-13-16(4-5-20(21)30-11-10-29-9-7-24)12-19-18-15-23(28-3)22(27-2)14-17(18)6-8-25-19/h4-6,8,13-15H,7,9-12H2,1-3H3
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n/an/a 2.52E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50351892
PNG
(CHEMBL1821791)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1
Show InChI InChI=1S/C19H19NO3/c1-21-15-6-4-13(5-7-15)10-17-16-12-19(23-3)18(22-2)11-14(16)8-9-20-17/h4-9,11-12H,10H2,1-3H3
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n/an/a 3.10E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50351892
PNG
(CHEMBL1821791)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1
Show InChI InChI=1S/C19H19NO3/c1-21-15-6-4-13(5-7-15)10-17-16-12-19(23-3)18(22-2)11-14(16)8-9-20-17/h4-9,11-12H,10H2,1-3H3
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n/an/a 3.98E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 21n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351891
PNG
(CHEMBL1821790)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCOCCF
Show InChI InChI=1S/C23H26FNO5/c1-26-21-13-16(4-5-20(21)30-11-10-29-9-7-24)12-19-18-15-23(28-3)22(27-2)14-17(18)6-8-25-19/h4-6,8,13-15H,7,9-12H2,1-3H3
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n/an/a 28n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351892
PNG
(CHEMBL1821791)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1
Show InChI InChI=1S/C19H19NO3/c1-21-15-6-4-13(5-7-15)10-17-16-12-19(23-3)18(22-2)11-14(16)8-9-20-17/h4-9,11-12H,10H2,1-3H3
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n/an/a 48.8n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351890
PNG
(CHEMBL1821787)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OCCF
Show InChI InChI=1S/C21H22FNO4/c1-24-18-5-4-14(11-21(18)27-9-7-22)10-17-16-13-20(26-3)19(25-2)12-15(16)6-8-23-17/h4-6,8,11-13H,7,9-10H2,1-3H3
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n/an/a 55n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351894
PNG
(CHEMBL1821789)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCF
Show InChI InChI=1S/C21H22FNO4/c1-24-19-11-14(4-5-18(19)27-9-7-22)10-17-16-13-21(26-3)20(25-2)12-15(16)6-8-23-17/h4-6,8,11-13H,7,9-10H2,1-3H3
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n/an/a 55n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 1


(Homo sapiens (Human)-Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 9.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human lung


J Med Chem 28: 537-45 (1985)


Article DOI: 10.1021/jm50001a001
BindingDB Entry DOI: 10.7270/Q2N58MXT
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351899
PNG
(CHEMBL1821779)
Show SMILES COc1cc2ccnc(Cc3ccc(SC)cc3)c2cc1OCCF
Show InChI InChI=1S/C20H20FNO2S/c1-23-19-12-15-7-9-22-18(17(15)13-20(19)24-10-8-21)11-14-3-5-16(25-2)6-4-14/h3-7,9,12-13H,8,10-11H2,1-2H3
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n/an/a 237n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351900
PNG
(CHEMBL1821778)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)cc1C
Show InChI InChI=1S/C21H22FNO3/c1-14-10-15(4-5-19(14)24-2)11-18-17-13-21(26-9-7-22)20(25-3)12-16(17)6-8-23-18/h4-6,8,10,12-13H,7,9,11H2,1-3H3
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n/an/a 244n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351901
PNG
(CHEMBL1821788)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OCCF)cc23)ccc1OCCF
Show InChI InChI=1S/C22H23F2NO4/c1-26-20-12-15(3-4-19(20)28-9-6-23)11-18-17-14-22(29-10-7-24)21(27-2)13-16(17)5-8-25-18/h3-5,8,12-14H,6-7,9-11H2,1-2H3
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n/an/a 246n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351903
PNG
(CHEMBL1821785)
Show SMILES COc1ccc(OC)c(Cc2nccc3cc(OC)c(OCCF)cc23)c1
Show InChI InChI=1S/C21H22FNO4/c1-24-16-4-5-19(25-2)15(10-16)11-18-17-13-21(27-9-7-22)20(26-3)12-14(17)6-8-23-18/h4-6,8,10,12-13H,7,9,11H2,1-3H3
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n/an/a 262n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351906
PNG
(CHEMBL1821780)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)c(F)c1
Show InChI InChI=1S/C20H19F2NO3/c1-24-15-4-3-14(17(22)11-15)9-18-16-12-20(26-8-6-21)19(25-2)10-13(16)5-7-23-18/h3-5,7,10-12H,6,8-9H2,1-2H3
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n/an/a 500n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 917n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 1.03E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50351908
PNG
(CHEMBL1821774)
Show SMILES COc1ccc(Cc2nccc3cc(OCCF)c(OC)cc23)cc1F
Show InChI InChI=1S/C20H19F2NO3/c1-24-18-4-3-13(9-16(18)22)10-17-15-12-19(25-2)20(26-8-6-21)11-14(15)5-7-23-17/h3-5,7,9,11-12H,6,8,10H2,1-2H3
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n/an/a 1.25E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50351908
PNG
(CHEMBL1821774)
Show SMILES COc1ccc(Cc2nccc3cc(OCCF)c(OC)cc23)cc1F
Show InChI InChI=1S/C20H19F2NO3/c1-24-18-4-3-13(9-16(18)22)10-17-15-12-19(25-2)20(26-8-6-21)11-14(15)5-7-23-17/h3-5,7,9,11-12H,6,8,10H2,1-2H3
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n/an/a 1.29E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50351894
PNG
(CHEMBL1821789)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCF
Show InChI InChI=1S/C21H22FNO4/c1-24-19-11-14(4-5-18(19)27-9-7-22)10-17-16-13-21(26-3)20(25-2)12-15(16)6-8-23-17/h4-6,8,11-13H,7,9-10H2,1-3H3
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n/an/a 1.74E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50351890
PNG
(CHEMBL1821787)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OCCF
Show InChI InChI=1S/C21H22FNO4/c1-24-18-5-4-14(11-21(18)27-9-7-22)10-17-16-13-20(26-3)19(25-2)12-15(16)6-8-23-17/h4-6,8,11-13H,7,9-10H2,1-3H3
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n/an/a 1.94E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50351894
PNG
(CHEMBL1821789)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCF
Show InChI InChI=1S/C21H22FNO4/c1-24-19-11-14(4-5-18(19)27-9-7-22)10-17-16-13-21(26-3)20(25-2)12-15(16)6-8-23-17/h4-6,8,11-13H,7,9-10H2,1-3H3
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n/an/a 2.17E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50351891
PNG
(CHEMBL1821790)
Show SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCOCCF
Show InChI InChI=1S/C23H26FNO5/c1-26-21-13-16(4-5-20(21)30-11-10-29-9-7-24)12-19-18-15-23(28-3)22(27-2)14-17(18)6-8-25-19/h4-6,8,13-15H,7,9-12H2,1-3H3
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n/an/a 2.20E+3n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
Phosphodiesterase Type 10 (PDE10A)


(Rattus norvegicus (rat))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 36n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of rat PDE10A


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50351908
PNG
(CHEMBL1821774)
Show SMILES COc1ccc(Cc2nccc3cc(OCCF)c(OC)cc23)cc1F
Show InChI InChI=1S/C20H19F2NO3/c1-24-18-4-3-13(9-16(18)22)10-17-15-12-19(25-2)20(26-8-6-21)11-14(15)5-7-23-17/h3-5,7,9,11-12H,6,8,10H2,1-2H3
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n/an/a 49n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay


Eur J Med Chem 46: 3986-95 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.072
BindingDB Entry DOI: 10.7270/Q279452C
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 36n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrs


Bioorg Med Chem Lett 22: 1944-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.046
BindingDB Entry DOI: 10.7270/Q2KH0NTP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 1.70E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of human lung


J Med Chem 28: 537-45 (1985)


Article DOI: 10.1021/jm50001a001
BindingDB Entry DOI: 10.7270/Q2N58MXT
More data for this
Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 2.30E+3n/an/an/an/an/an/a



Eisai Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cGMP-stimulated phosphodiesterase 2 of porcine coronary arteries


J Med Chem 36: 3765-70 (1994)


Article DOI: 10.1021/jm00076a003
BindingDB Entry DOI: 10.7270/Q279459H
More data for this
Ligand-Target Pair
Phosphodiesterase 3A


(Sus scrofa)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 620n/an/an/an/an/an/a



Eisai Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cGMP-inhibited phosphodiesterase from porcine coronary arteries


J Med Chem 36: 3765-70 (1994)


Article DOI: 10.1021/jm00076a003
BindingDB Entry DOI: 10.7270/Q279459H
More data for this
Ligand-Target Pair
Phosphodiesterase 4A


(Sus scrofa)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 1.70E+3n/an/an/an/an/an/a



Eisai Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of cAMP specific phosphodiesterase from porcine coronary arteries


J Med Chem 36: 3765-70 (1994)


Article DOI: 10.1021/jm00076a003
BindingDB Entry DOI: 10.7270/Q279459H
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 2.43E+4n/an/an/an/an/an/a



Naresuan University

Curated by ChEMBL


Assay Description
Inhibition of AChE activity


Bioorg Med Chem Lett 16: 2170-2 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.067
BindingDB Entry DOI: 10.7270/Q2NC621V
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 284n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE3A


J Med Chem 55: 7299-331 (2012)


Article DOI: 10.1021/jm3004976
BindingDB Entry DOI: 10.7270/Q2C24XJK
More data for this
Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 40n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE10A


J Med Chem 55: 7299-331 (2012)


Article DOI: 10.1021/jm3004976
BindingDB Entry DOI: 10.7270/Q2C24XJK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 7.24E+3n/an/an/an/an/an/a



TCG Lifesciences Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human ERG


Eur J Med Chem 46: 618-30 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.042
BindingDB Entry DOI: 10.7270/Q2WQ052W
More data for this
Ligand-Target Pair
Phosphodiesterase (TcrPDEC)


(Trypanosoma cruzi)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 2.50E+4n/an/an/an/a7.524



University of North Carolina



Assay Description
Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.


J Biol Chem 287: 11788-97 (2012)


Article DOI: 10.1074/jbc.M111.326777
BindingDB Entry DOI: 10.7270/Q2K9364D
More data for this
Ligand-Target Pair
protein-arginine deiminase type-4


(Homo sapiens)
BDBM14754
PNG
(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)
Show SMILES COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
Show InChI InChI=1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
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n/an/a 3.90E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2PK0DMQ
More data for this
Ligand-Target Pair
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