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15 molecules are shown

Wt: 385.4
BDBM15191
Wt: 399.5
BDBM15192
Wt: 399.5
BDBM15193
Wt: 399.5
BDBM15194
Wt: 419.9
BDBM15195
Wt: 419.9
BDBM15196
Wt: 454.3
BDBM15198
Wt: 415.5
BDBM15199
Wt: 415.5
BDBM15200
Wt: 415.5
BDBM15201
Wt: 431.9
BDBM15213
Wt: 431.9
BDBM15214
Wt: 431.9
BDBM15215
Wt: 445.9
BDBM15219
Wt: 419.9
BDBM16222

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 15191,15192,15193,15194,15195,15196,15198,15199,15200,15201,15213,15214,15215,15219,16222   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM16222
PNG
(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-6-4-16(5-7-18)15-27-13-12-22-10-11-24-28(25,26)20-3-1-2-17-14-23-9-8-19(17)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 260n/an/an/an/a7.222



Astex



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


J Med Chem 50: 2289-92 (2007)


Article DOI: 10.1021/jm0700924
BindingDB Entry DOI: 10.7270/Q2M32T1C
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM16222
PNG
(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-6-4-16(5-7-18)15-27-13-12-22-10-11-24-28(25,26)20-3-1-2-17-14-23-9-8-19(17)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 170n/an/an/an/a7.222



Astex



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


J Mol Biol 367: 882-94 (2007)


Article DOI: 10.1016/j.jmb.2007.01.004
BindingDB Entry DOI: 10.7270/Q29Z934H
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15191
PNG
(Isoquinoline-5-sulfonic acid (2-(2-benzyloxyethyla...)
Show SMILES O=S(=O)(NCCNCCOCc1ccccc1)c1cccc2cnccc12
Show InChI InChI=1S/C20H23N3O3S/c24-27(25,20-8-4-7-18-15-22-10-9-19(18)20)23-12-11-21-13-14-26-16-17-5-2-1-3-6-17/h1-10,15,21,23H,11-14,16H2
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n/an/a 1.17E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15192
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(2-methylbenzyl...)
Show SMILES Cc1ccccc1COCCNCCNS(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C21H25N3O3S/c1-17-5-2-3-6-19(17)16-27-14-13-22-11-12-24-28(25,26)21-8-4-7-18-15-23-10-9-20(18)21/h2-10,15,22,24H,11-14,16H2,1H3
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n/an/a 570n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15193
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(3-methylbenzyl...)
Show SMILES Cc1cccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)c1
Show InChI InChI=1S/C21H25N3O3S/c1-17-4-2-5-18(14-17)16-27-13-12-22-10-11-24-28(25,26)21-7-3-6-19-15-23-9-8-20(19)21/h2-9,14-15,22,24H,10-13,16H2,1H3
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n/an/a 1.10E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15194
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(4-methylbenzyl...)
Show SMILES Cc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C21H25N3O3S/c1-17-5-7-18(8-6-17)16-27-14-13-22-11-12-24-28(25,26)21-4-2-3-19-15-23-10-9-20(19)21/h2-10,15,22,24H,11-14,16H2,1H3
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n/an/a 1.53E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15195
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(2-chlorobenzyl...)
Show SMILES Clc1ccccc1COCCNCCNS(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C20H22ClN3O3S/c21-19-6-2-1-4-17(19)15-27-13-12-22-10-11-24-28(25,26)20-7-3-5-16-14-23-9-8-18(16)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 960n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15196
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(3-chlorobenzyl...)
Show SMILES Clc1cccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)c1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-5-1-3-16(13-18)15-27-12-11-22-9-10-24-28(25,26)20-6-2-4-17-14-23-8-7-19(17)20/h1-8,13-14,22,24H,9-12,15H2
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n/an/a 370n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM16222
PNG
(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-6-4-16(5-7-18)15-27-13-12-22-10-11-24-28(25,26)20-3-1-2-17-14-23-9-8-19(17)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 260n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15198
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(3,4-dichlorobe...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1Cl
Show InChI InChI=1S/C20H21Cl2N3O3S/c21-18-5-4-15(12-19(18)22)14-28-11-10-23-8-9-25-29(26,27)20-3-1-2-16-13-24-7-6-17(16)20/h1-7,12-13,23,25H,8-11,14H2
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n/an/a 210n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15199
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(2-methoxybenzy...)
Show SMILES COc1ccccc1COCCNCCNS(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C21H25N3O4S/c1-27-20-7-3-2-5-18(20)16-28-14-13-22-11-12-24-29(25,26)21-8-4-6-17-15-23-10-9-19(17)21/h2-10,15,22,24H,11-14,16H2,1H3
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n/an/a 6.60E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15200
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(3-methoxybenzy...)
Show SMILES COc1cccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)c1
Show InChI InChI=1S/C21H25N3O4S/c1-27-19-6-2-4-17(14-19)16-28-13-12-22-10-11-24-29(25,26)21-7-3-5-18-15-23-9-8-20(18)21/h2-9,14-15,22,24H,10-13,16H2,1H3
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n/an/a 2.20E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15201
PNG
(N-[2-({2-[(4-methoxyphenyl)methoxy]ethyl}amino)eth...)
Show SMILES COc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C21H25N3O4S/c1-27-19-7-5-17(6-8-19)16-28-14-13-22-11-12-24-29(25,26)21-4-2-3-18-15-23-10-9-20(18)21/h2-10,15,22,24H,11-14,16H2,1H3
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n/an/a 2.90E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM15195
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(2-chlorobenzyl...)
Show SMILES Clc1ccccc1COCCNCCNS(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C20H22ClN3O3S/c21-19-6-2-1-4-17(19)15-27-13-12-22-10-11-24-28(25,26)20-7-3-5-16-14-23-9-8-18(16)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 1.00E+3n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM15196
PNG
(Isoquinoline-5-sulfonic acid (2-(2-(3-chlorobenzyl...)
Show SMILES Clc1cccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)c1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-5-1-3-16(13-18)15-27-12-11-22-9-10-24-28(25,26)20-6-2-4-17-14-23-8-7-19(17)20/h1-8,13-14,22,24H,9-12,15H2
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n/an/a 410n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM16222
PNG
(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-6-4-16(5-7-18)15-27-13-12-22-10-11-24-28(25,26)20-3-1-2-17-14-23-9-8-19(17)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 170n/an/an/an/a7.222



UK Centre for Cancer Therapeutics



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15213
PNG
(5-[(3-{[(4-chlorophenyl)methoxy]methyl}piperazine-...)
Show SMILES Clc1ccc(COCC2CN(CCN2)S(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C21H22ClN3O3S/c22-18-6-4-16(5-7-18)14-28-15-19-13-25(11-10-24-19)29(26,27)21-3-1-2-17-12-23-9-8-20(17)21/h1-9,12,19,24H,10-11,13-15H2
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n/an/a 1.20E+4n/an/an/an/an/an/a



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15214
PNG
(Isoquinoline-5-sulfonic acid (2S,4R)-[2-(4-chlorob...)
Show SMILES Clc1ccc(COC[C@@H]2C[C@H](CN2)NS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C21H22ClN3O3S/c22-17-6-4-15(5-7-17)13-28-14-19-10-18(12-24-19)25-29(26,27)21-3-1-2-16-11-23-9-8-20(16)21/h1-9,11,18-19,24-25H,10,12-14H2/t18-,19+/m1/s1
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n/an/a 5.20E+3n/an/an/an/an/an/a



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15215
PNG
(Isoquinoline-5-sulfonic acid (2S,4S)-(2-(4-chlorob...)
Show SMILES Clc1ccc(COC[C@@H]2C[C@@H](CN2)NS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C21H22ClN3O3S/c22-17-6-4-15(5-7-17)13-28-14-19-10-18(12-24-19)25-29(26,27)21-3-1-2-16-11-23-9-8-20(16)21/h1-9,11,18-19,24-25H,10,12-14H2/t18-,19-/m0/s1
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n/an/a 780n/an/an/an/an/an/a



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM15219
PNG
(Isoquinoline-5-sulfonic acid (2R*,5S*)-(5-(4-chlor...)
Show SMILES Clc1ccc(COC[C@@H]2CC[C@H](CNS(=O)(=O)c3cccc4cnccc34)N2)cc1
Show InChI InChI=1S/C22H24ClN3O3S/c23-18-6-4-16(5-7-18)14-29-15-20-9-8-19(26-20)13-25-30(27,28)22-3-1-2-17-12-24-11-10-21(17)22/h1-7,10-12,19-20,25-26H,8-9,13-15H2/t19-,20+/m1/s1
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n/an/a 1.70E+3n/an/an/an/an/an/a



UK Centre for Cancer Therapeutics



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM15215
PNG
(Isoquinoline-5-sulfonic acid (2S,4S)-(2-(4-chlorob...)
Show SMILES Clc1ccc(COC[C@@H]2C[C@@H](CN2)NS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C21H22ClN3O3S/c22-17-6-4-15(5-7-17)13-28-14-19-10-18(12-24-19)25-29(26,27)21-3-1-2-16-11-23-9-8-20(16)21/h1-9,11,18-19,24-25H,10,12-14H2/t18-,19-/m0/s1
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n/an/a 420n/an/an/an/an/an/a



UK Centre for Cancer Therapeutics



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


Bioorg Med Chem 14: 1255-73 (2006)


Article DOI: 10.1016/j.bmc.2005.09.055
BindingDB Entry DOI: 10.7270/Q2FN14F2
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase AKT


(Homo sapiens (human))
BDBM16222
PNG
(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-6-4-16(5-7-18)15-27-13-12-22-10-11-24-28(25,26)20-3-1-2-17-14-23-9-8-19(17)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 230n/an/an/an/a7.222



Astex



Assay Description
The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...


J Mol Biol 367: 882-94 (2007)


Article DOI: 10.1016/j.jmb.2007.01.004
BindingDB Entry DOI: 10.7270/Q29Z934H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
cAMP-Dependent Protein Kinase (PKA)


(Bos taurus (bovine))
BDBM16222
PNG
(CCT077373 | N-[2-({2-[(4-chlorobenzyl)oxy]ethyl}am...)
Show SMILES Clc1ccc(COCCNCCNS(=O)(=O)c2cccc3cnccc23)cc1
Show InChI InChI=1S/C20H22ClN3O3S/c21-18-6-4-16(5-7-18)15-27-13-12-22-10-11-24-28(25,26)20-3-1-2-17-14-23-9-8-19(17)20/h1-9,14,22,24H,10-13,15H2
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n/an/a 170n/an/an/an/a7.222



Astex



Assay Description
The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...


J Med Chem 50: 2289-92 (2007)


Article DOI: 10.1021/jm0700924
BindingDB Entry DOI: 10.7270/Q2M32T1C
More data for this
Ligand-Target Pair