BindingDB logo
myBDB logout

1 similar compounds to monomer 50438386

Compile data set for download or QSAR
Wt: 178.3
BDBM152726

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152726   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 8


(Homo sapiens (Human))
BDBM152726
PNG
((3-azaniumylpropyl)(5-sulfanylpentyl)azanium (2))
Show SMILES [NH3+]CCC[NH2+]CCCCCS
Show InChI InChI=1S/C8H20N2S/c9-5-4-7-10-6-2-1-3-8-11/h10-11H,1-9H2/p+2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/a8.2n/a



University of Pennsylvania



Assay Description
Activity assays were conducted at 25 C and contained 500 nM HDAC8 enzyme, 150 μM Ac-Arg-His-Lys(Ac)-Lys(Ac)-aminomethylcoumarin substrate (BML-...


Biochemistry 54: 4692-703 (2015)


Article DOI: 10.1021/acs.biochem.5b00536
BindingDB Entry DOI: 10.7270/Q2FN14ZS
More data for this
Ligand-Target Pair