BindingDB logo
myBDB logout

12 similar compounds to monomer 176499

Compile data set for download or QSAR
Wt: 395.3
BDBM176508
Wt: 471.4
BDBM176509
Wt: 436.4
BDBM176511
Wt: 482.4
BDBM176536
Wt: 482.4
BDBM176537
Wt: 379.3
BDBM176498
Wt: 395.3
BDBM176500
Wt: 455.4
BDBM176501
Wt: 405.4
BDBM176502
Wt: 409.4
BDBM176503
Wt: 421.4
BDBM176504
Wt: 407.4
BDBM176507

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 176508,176509,176511,176536,176537,176498,176500,176501,176502,176503,176504,176507   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176498
PNG
(US9120752, 38 | US9765029, 38)
Show SMILES C[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C21H18FN3O3/c1-13(20(23)26)24-21(27)19-4-2-3-18(25-19)14-5-9-16(10-6-14)28-17-11-7-15(22)8-12-17/h2-13H,1H3,(H2,23,26)(H,24,27)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 310n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176536
PNG
(US9120752, 64 | US9765029, 64)
Show SMILES NC(=O)C[C@H](NC(=O)c1cc(cc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)[C@H](O)CO)C(N)=O
Show InChI InChI=1S/C24H23FN4O6/c25-15-3-7-17(8-4-15)35-16-5-1-13(2-6-16)18-9-14(21(31)12-30)10-20(28-18)24(34)29-19(23(27)33)11-22(26)32/h1-10,19,21,30-31H,11-12H2,(H2,26,32)(H2,27,33)(H,29,34)/t19-,21+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>2.00E+4n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176501
PNG
(US9120752, 41 | US9765029, 41)
Show SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H22FN3O3/c28-20-11-15-22(16-12-20)34-21-13-9-19(10-14-21)23-7-4-8-24(30-23)27(33)31-25(26(29)32)17-18-5-2-1-3-6-18/h1-16,25H,17H2,(H2,29,32)(H,31,33)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>2.00E+4n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176502
PNG
(US9120752, 42 | US9765029, 42)
Show SMILES NC(=O)[C@@H]1CCCN1C(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C23H20FN3O3/c24-16-8-12-18(13-9-16)30-17-10-6-15(7-11-17)19-3-1-4-20(26-19)23(29)27-14-2-5-21(27)22(25)28/h1,3-4,6-13,21H,2,5,14H2,(H2,25,28)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.12E+3n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176503
PNG
(US9120752, 43 | US9765029, 43)
Show SMILES CC(O)[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C22H20FN3O4/c1-13(27)20(21(24)28)26-22(29)19-4-2-3-18(25-19)14-5-9-16(10-6-14)30-17-11-7-15(23)8-12-17/h2-13,20,27H,1H3,(H2,24,28)(H,26,29)/t13?,20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.56E+3n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176504
PNG
(US9120752, 44 | US9765029, 44)
Show SMILES CC(C)C[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C24H24FN3O3/c1-15(2)14-22(23(26)29)28-24(30)21-5-3-4-20(27-21)16-6-10-18(11-7-16)31-19-12-8-17(25)9-13-19/h3-13,15,22H,14H2,1-2H3,(H2,26,29)(H,28,30)/t22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 340n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176507
PNG
(US9120752, 46 | US9765029, 46)
Show SMILES CC(C)[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C23H22FN3O3/c1-14(2)21(22(25)28)27-23(29)20-5-3-4-19(26-20)15-6-10-17(11-7-15)30-18-12-8-16(24)9-13-18/h3-14,21H,1-2H3,(H2,25,28)(H,27,29)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 610n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176508
PNG
(US9120752, 47 | US9765029, 47)
Show SMILES NC(=O)[C@H](CO)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H18FN3O4/c22-14-6-10-16(11-7-14)29-15-8-4-13(5-9-15)17-2-1-3-18(24-17)21(28)25-19(12-26)20(23)27/h1-11,19,26H,12H2,(H2,23,27)(H,25,28)/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.53E+3n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176509
PNG
(US9120752, 48 | US9765029, 51)
Show SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H22FN3O4/c28-19-8-14-22(15-9-19)35-21-12-6-18(7-13-21)23-2-1-3-24(30-23)27(34)31-25(26(29)33)16-17-4-10-20(32)11-5-17/h1-15,25,32H,16H2,(H2,29,33)(H,31,34)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 550n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176511
PNG
(US9120752, 51)
Show SMILES NCCCC[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C24H25FN4O3/c25-17-9-13-19(14-10-17)32-18-11-7-16(8-12-18)20-5-3-6-22(28-20)24(31)29-21(23(27)30)4-1-2-15-26/h3,5-14,21H,1-2,4,15,26H2,(H2,27,30)(H,29,31)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.89E+3n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176536
PNG
(US9120752, 64 | US9765029, 64)
Show SMILES NC(=O)C[C@H](NC(=O)c1cc(cc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)[C@H](O)CO)C(N)=O
Show InChI InChI=1S/C24H23FN4O6/c25-15-3-7-17(8-4-15)35-16-5-1-13(2-6-16)18-9-14(21(31)12-30)10-20(28-18)24(34)29-19(23(27)33)11-22(26)32/h1-10,19,21,30-31H,11-12H2,(H2,26,32)(H2,27,33)(H,29,34)/t19-,21+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>2.00E+4n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176537
PNG
(US9120752, 66)
Show SMILES NC(=O)C[C@H](NC(=O)c1cc(cc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)[C@@H](O)CO)C(N)=O
Show InChI InChI=1S/C24H23FN4O6/c25-15-3-7-17(8-4-15)35-16-5-1-13(2-6-16)18-9-14(21(31)12-30)10-20(28-18)24(34)29-19(23(27)33)11-22(26)32/h1-10,19,21,30-31H,11-12H2,(H2,26,32)(H2,27,33)(H,29,34)/t19-,21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>2.00E+4n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176498
PNG
(US9120752, 38 | US9765029, 38)
Show SMILES C[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C21H18FN3O3/c1-13(20(23)26)24-21(27)19-4-2-3-18(25-19)14-5-9-16(10-6-14)28-17-11-7-15(22)8-12-17/h2-13H,1H3,(H2,23,26)(H,24,27)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 310n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176500
PNG
(US9120752, 40 | US9765029, 40)
Show SMILES NC(=O)[C@@H](CO)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H18FN3O4/c22-14-6-10-16(11-7-14)29-15-8-4-13(5-9-15)17-2-1-3-18(24-17)21(28)25-19(12-26)20(23)27/h1-11,19,26H,12H2,(H2,23,27)(H,25,28)/t19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.32E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176501
PNG
(US9120752, 41 | US9765029, 41)
Show SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H22FN3O3/c28-20-11-15-22(16-12-20)34-21-13-9-19(10-14-21)23-7-4-8-24(30-23)27(33)31-25(26(29)32)17-18-5-2-1-3-6-18/h1-16,25H,17H2,(H2,29,32)(H,31,33)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>2.00E+4n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176502
PNG
(US9120752, 42 | US9765029, 42)
Show SMILES NC(=O)[C@@H]1CCCN1C(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C23H20FN3O3/c24-16-8-12-18(13-9-16)30-17-10-6-15(7-11-17)19-3-1-4-20(26-19)23(29)27-14-2-5-21(27)22(25)28/h1,3-4,6-13,21H,2,5,14H2,(H2,25,28)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.12E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176503
PNG
(US9120752, 43 | US9765029, 43)
Show SMILES CC(O)[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C22H20FN3O4/c1-13(27)20(21(24)28)26-22(29)19-4-2-3-18(25-19)14-5-9-16(10-6-14)30-17-11-7-15(23)8-12-17/h2-13,20,27H,1H3,(H2,24,28)(H,26,29)/t13?,20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.56E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176504
PNG
(US9120752, 44 | US9765029, 44)
Show SMILES CC(C)C[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C24H24FN3O3/c1-15(2)14-22(23(26)29)28-24(30)21-5-3-4-20(27-21)16-6-10-18(11-7-16)31-19-12-8-17(25)9-13-19/h3-13,15,22H,14H2,1-2H3,(H2,26,29)(H,28,30)/t22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 340n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176507
PNG
(US9120752, 46 | US9765029, 46)
Show SMILES CC(C)[C@H](NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O
Show InChI InChI=1S/C23H22FN3O3/c1-14(2)21(22(25)28)27-23(29)20-5-3-4-19(26-20)15-6-10-17(11-7-15)30-18-12-8-16(24)9-13-18/h3-14,21H,1-2H3,(H2,25,28)(H,27,29)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 610n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176508
PNG
(US9120752, 47 | US9765029, 47)
Show SMILES NC(=O)[C@H](CO)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H18FN3O4/c22-14-6-10-16(11-7-14)29-15-8-4-13(5-9-15)17-2-1-3-18(24-17)21(28)25-19(12-26)20(23)27/h1-11,19,26H,12H2,(H2,23,27)(H,25,28)/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.53E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176509
PNG
(US9120752, 48 | US9765029, 51)
Show SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H22FN3O4/c28-19-8-14-22(15-9-19)35-21-12-6-18(7-13-21)23-2-1-3-24(30-23)27(34)31-25(26(29)33)16-17-4-10-20(32)11-5-17/h1-15,25,32H,16H2,(H2,29,33)(H,31,34)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 550n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176509
PNG
(US9120752, 48 | US9765029, 51)
Show SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H22FN3O4/c28-19-8-14-22(15-9-19)35-21-12-6-18(7-13-21)23-2-1-3-24(30-23)27(34)31-25(26(29)33)16-17-4-10-20(32)11-5-17/h1-15,25,32H,16H2,(H2,29,33)(H,31,34)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 330n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176509
PNG
(US9120752, 48 | US9765029, 51)
Show SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C27H22FN3O4/c28-19-8-14-22(15-9-19)35-21-12-6-18(7-13-21)23-2-1-3-24(30-23)27(34)31-25(26(29)33)16-17-4-10-20(32)11-5-17/h1-15,25,32H,16H2,(H2,29,33)(H,31,34)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.89E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

US Patent


Assay Description
The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...


US Patent US9765029 (2017)

More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM176500
PNG
(US9120752, 40 | US9765029, 40)
Show SMILES NC(=O)[C@@H](CO)NC(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H18FN3O4/c22-14-6-10-16(11-7-14)29-15-8-4-13(5-9-15)17-2-1-3-18(24-17)21(28)25-19(12-26)20(23)27/h1-11,19,26H,12H2,(H2,23,27)(H,25,28)/t19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.32E+3n/an/an/an/an/a37



Purdue Pharma, L.P.

US Patent


Assay Description
Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...


US Patent US9120752 (2015)


BindingDB Entry DOI: 10.7270/Q2B56HHN
More data for this
Ligand-Target Pair