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7 similar compounds to monomer 18073

Compile data set for download or QSAR
Wt: 181.1
BDBM18129
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Wt: 165.1
BDBM36161
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Wt: 180.2
BDBM36094
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Wt: 180.2
BDBM36095
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Wt: 165.1
BDBM92701
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Wt: 181.1
BDBM92702
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Wt: 223.2
BDBM50075016

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 18129,36161,36094,36095,92701,92702,50075016   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin--tyrosine ligase


(Homo sapiens)
BDBM18129
PNG
((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
Show SMILES N[C@@H](Cc1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
2.50E+4 -6.53n/an/an/an/an/a6.837



Binghamton University



Assay Description
Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).


ACS Chem Biol 5: 777-85 (2010)


Article DOI: 10.1021/cb100060v
BindingDB Entry DOI: 10.7270/Q25H7DM1
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92702
PNG
(L-Tyrosine, 24)
Show SMILES [NH3+]C(Cc1ccc(O)cc1)C([O-])=O
Show InChI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a>3.00E+6n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)


BindingDB Entry DOI: 10.7270/Q25T3J3J
More data for this
Ligand-Target Pair
Grb2-SH2


(Homo sapiens (human))
BDBM50075016
PNG
(2-Amino-3-(4-carboxymethyl-phenyl)-propionic acid ...)
Show SMILES NC(Cc1ccc(CC(O)=O)cc1)C(O)=O
Show InChI InChI=1S/C11H13NO4/c12-9(11(15)16)5-7-1-3-8(4-2-7)6-10(13)14/h1-4,9H,5-6,12H2,(H,13,14)(H,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 6.50E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound against Growth factor receptor bound protein 2 in MDA-MB-453 cells


Bioorg Med Chem Lett 9: 347-52 (1999)


Article DOI: 10.1016/s0960-894x(98)00740-9
BindingDB Entry DOI: 10.7270/Q2VM4BF2
More data for this
Ligand-Target Pair
Trp Aprorepressor


(Escherichia coli (strain K12))
BDBM92701
PNG
(L-Phenylalanine, 23)
Show SMILES [NH3+]C(Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/a>3.00E+6n/an/an/an/an/a



University of Chicago



Assay Description
Binding assay of L-trptophan and analogues to trp aporepressor


J Biol Chem 262: 4922-7 (1987)


BindingDB Entry DOI: 10.7270/Q25T3J3J
More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 3 hits for monomerid = 18129,36161,36094,36095,92701,92702,50075016
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
BDBM11
JPEG
BDBM36094
JPEG
CHEBI
KEGG
MMDB
PC cid
PC sid
PC cid
PC sid
-1.41-0.0712-1.341.044.8025



Japan Science and Technology Agency





J Am Chem Soc 122: 4418-35 (2000)

BDBM11
JPEG
BDBM36095
JPEG
CHEBI
KEGG
MMDB
PC cid
PC sid
PC cid
PC sid
-1.48-0.285-1.191.084.8025



Japan Science and Technology Agency





J Am Chem Soc 122: 4418-35 (2000)

BDBM4
JPEG
BDBM36161
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
CHEBI
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
-1.242.35-3.580.9035.0125



NIST





J Phys Chem 98: 10282-10288 (1994)