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1 similar compounds to monomer 183098

Compile data set for download or QSAR
Wt: 463.9
BDBM183086

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183086   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183086
PNG
(US9150546, I-164 | US9688643, I-164 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cn2)c1=O
Show InChI InChI=1S/C24H22ClN5O3/c1-16(2)30-23(31)28-22(29(24(30)32)15-19-9-8-17(25)14-26-19)27-18-10-12-21(13-11-18)33-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,27,28,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 860n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM183086
PNG
(US9150546, I-164 | US9688643, I-164 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cn2)c1=O
Show InChI InChI=1S/C24H22ClN5O3/c1-16(2)30-23(31)28-22(29(24(30)32)15-19-9-8-17(25)14-26-19)27-18-10-12-21(13-11-18)33-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,27,28,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 860n/an/an/an/a7.5n/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...


US Patent US9718790 (2017)

More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM183086
PNG
(US9150546, I-164 | US9688643, I-164 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cn2)c1=O
Show InChI InChI=1S/C24H22ClN5O3/c1-16(2)30-23(31)28-22(29(24(30)32)15-19-9-8-17(25)14-26-19)27-18-10-12-21(13-11-18)33-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,27,28,31)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 860n/an/an/an/an/an/a



SRMLSC

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9688643 (2017)


BindingDB Entry DOI: 10.7270/Q2M32SZ2
More data for this
Ligand-Target Pair