BindingDB logo
myBDB logout

14 similar compounds to monomer 184295

Compile data set for download or QSAR
Wt: 338.3
BDBM184341
Wt: 324.3
BDBM184262
Wt: 352.3
BDBM184281
Wt: 338.3
BDBM184283
Wt: 338.3
BDBM184292
Wt: 352.3
BDBM184293
Wt: 338.3
BDBM184296
Wt: 338.3
BDBM184297
Wt: 324.3
BDBM184298
Wt: 366.4
BDBM184300
Wt: 338.3
BDBM184305
Wt: 324.3
BDBM184158
Wt: 338.3
BDBM184256
Wt: 324.3
BDBM184258

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 184341,184262,184281,184283,184292,184293,184296,184297,184298,184300,184305,184158,184256,184258   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184158
PNG
(US9150577, 2)
Show SMILES Cc1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)no1
Show InChI InChI=1S/C17H16N4O3/c1-10-7-15(20-24-10)19-16(22)12-4-3-11-8-14-17(23)18-5-2-6-21(14)13(11)9-12/h3-4,7-9H,2,5-6H2,1H3,(H,18,23)(H,19,20,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184256
PNG
(US9150577, 126)
Show SMILES Cc1cc(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)n4c3c2)no1
Show InChI InChI=1S/C18H18N4O3/c1-10-6-15(21-25-10)20-16(23)12-5-4-11-7-14-17(24)19-9-18(2,3)22(14)13(11)8-12/h4-8H,9H2,1-3H3,(H,19,24)(H,20,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 36n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184258
PNG
(US9150577, 128)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C17H16N4O3/c1-9-8-18-17(23)14-6-11-3-4-12(7-13(11)21(9)14)16(22)19-15-5-10(2)24-20-15/h3-7,9H,8H2,1-2H3,(H,18,23)(H,19,20,22)/t9-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184262
PNG
(US9150577, 132)
Show SMILES C[C@H]1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C17H16N4O3/c1-9-8-18-17(23)14-6-11-3-4-12(7-13(11)21(9)14)16(22)19-15-5-10(2)24-20-15/h3-7,9H,8H2,1-2H3,(H,18,23)(H,19,20,22)/t9-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 495n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184281
PNG
(US9150577, 157)
Show SMILES Cc1cc(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)Cn4c3c2)no1
Show InChI InChI=1S/C19H20N4O3/c1-11-6-16(22-26-11)21-17(24)13-5-4-12-7-15-18(25)20-9-19(2,3)10-23(15)14(12)8-13/h4-8H,9-10H2,1-3H3,(H,20,25)(H,21,22,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.80E+3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184283
PNG
(US9150577, 159)
Show SMILES CC1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H18N4O3/c1-10-5-6-19-18(24)15-8-12-3-4-13(9-14(12)22(10)15)17(23)20-16-7-11(2)25-21-16/h3-4,7-10H,5-6H2,1-2H3,(H,19,24)(H,20,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 12n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184341
PNG
(US9150577, 225)
Show SMILES C[C@@H]1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H18N4O3/c1-10-5-6-19-18(24)15-8-12-3-4-13(9-14(12)22(10)15)17(23)20-16-7-11(2)25-21-16/h3-4,7-10H,5-6H2,1-2H3,(H,19,24)(H,20,21,23)/t10-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 12n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184293
PNG
(US9150577, 169)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C19H20N4O3/c1-10-9-20-19(25)16-7-13-4-5-14(8-15(13)23(16)12(10)3)18(24)21-17-6-11(2)26-22-17/h4-8,10,12H,9H2,1-3H3,(H,20,25)(H,21,22,24)/t10-,12+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 570n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184296
PNG
(US9150577, 172)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H18N4O3/c1-9-6-16(21-25-9)20-17(23)13-5-4-12-7-15-18(24)19-10(2)11(3)22(15)14(12)8-13/h4-8,10-11H,1-3H3,(H,19,24)(H,20,21,23)/t10-,11+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.10E+3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184297
PNG
(US9150577, 173)
Show SMILES C[C@H]1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H18N4O3/c1-10-5-6-19-18(24)15-8-12-3-4-13(9-14(12)22(10)15)17(23)20-16-7-11(2)25-21-16/h3-4,7-10H,5-6H2,1-2H3,(H,19,24)(H,20,21,23)/t10-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.20E+3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184298
PNG
(US9150577, 174)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C17H16N4O3/c1-9-8-18-17(23)14-6-11-3-4-12(7-13(11)21(9)14)16(22)19-15-5-10(2)24-20-15/h3-7,9H,8H2,1-2H3,(H,18,23)(H,19,20,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 34n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184300
PNG
(US9150577, 176)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cc(on1)C(C)(C)C
Show InChI InChI=1S/C20H22N4O3/c1-11-10-21-19(26)15-7-12-5-6-13(8-14(12)24(11)15)18(25)22-17-9-16(27-23-17)20(2,3)4/h5-9,11H,10H2,1-4H3,(H,21,26)(H,22,23,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 25n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184305
PNG
(US9150577, 182)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H18N4O3/c1-10-8-19-18(24)15-6-12-3-4-13(7-14(12)22(15)9-10)17(23)20-16-5-11(2)25-21-16/h3-7,10H,8-9H2,1-2H3,(H,19,24)(H,20,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 150n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184292
PNG
(US9150577, 168)
Show SMILES C[C@@H]1NC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cc(C)on1
Show InChI InChI=1S/C18H18N4O3/c1-9-6-16(21-25-9)20-17(23)13-5-4-12-7-15-18(24)19-10(2)11(3)22(15)14(12)8-13/h4-8,10-11H,1-3H3,(H,19,24)(H,20,21,23)/t10-,11-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 160n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair