BindingDB logo
myBDB logout

1 similar compounds to monomer 184192

Compile data set for download or QSAR
Wt: 519.4
BDBM184249

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184249   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184249
PNG
(US9150577, 118)
Show SMILES CS(=O)(=O)c1ccc2n(CC(F)(F)F)c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C23H20F3N5O4S/c1-36(34,35)15-5-6-17-16(11-15)28-22(31(17)12-23(24,25)26)29-20(32)14-4-3-13-9-19-21(33)27-7-2-8-30(19)18(13)10-14/h3-6,9-11H,2,7-8,12H2,1H3,(H,27,33)(H,28,29,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 18n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair