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25 similar compounds to monomer 188247

Compile data set for download or QSAR
Wt: 404.5
BDBM188228
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Wt: 404.5
BDBM188229
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Wt: 404.5
BDBM188230
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Wt: 455.5
BDBM188231
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Wt: 404.5
BDBM188232
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Wt: 422.5
BDBM188233
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Wt: 394.4
BDBM188235
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Wt: 410.9
BDBM188236
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Wt: 455.3
BDBM188237
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Wt: 420.5
BDBM188238
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Wt: 406.4
BDBM188239
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Wt: 410.9
BDBM188240
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Wt: 394.4
BDBM188242
Wt: 448.5
BDBM188243
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Wt: 433.5
BDBM188244
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Displayed 1 to 15 (of 25 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 188228,188229,188230,188231,188232,188233,188235,188236,188237,188238,188239,188240,188242,188243,188244   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188228
PNG
(US9073941, 510)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1ccc(C)c(C)c1
Show InChI InChI=1S/C20H28N4O3S/c1-14(2)23-12-19(21-13-23)28(26,27)24-9-7-17(8-10-24)20(25)22-18-6-5-15(3)16(4)11-18/h5-6,11-14,17H,7-10H2,1-4H3,(H,22,25)
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n/an/a 2.45E+3n/an/an/an/a7.0n/a



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US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188244
PNG
(US9073941, 526)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1ccc(C)c(c1)N(C)C
Show InChI InChI=1S/C21H31N5O3S/c1-15(2)25-13-20(22-14-25)30(28,29)26-10-8-17(9-11-26)21(27)23-18-7-6-16(3)19(12-18)24(4)5/h6-7,12-15,17H,8-11H2,1-5H3,(H,23,27)
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n/an/a 2.79E+3n/an/an/an/a7.0n/a



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Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188230
PNG
(US9073941, 512)
Show SMILES CCc1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cn(cn2)C(C)C)cc1
Show InChI InChI=1S/C20H28N4O3S/c1-4-16-5-7-18(8-6-16)22-20(25)17-9-11-24(12-10-17)28(26,27)19-13-23(14-21-19)15(2)3/h5-8,13-15,17H,4,9-12H2,1-3H3,(H,22,25)
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n/an/a 2.90E+3n/an/an/an/a7.0n/a



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Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188231
PNG
(US9073941, 513)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H25N5O5S2/c1-13(2)22-11-17(20-12-22)30(27,28)23-9-7-14(8-10-23)18(24)21-15-3-5-16(6-4-15)29(19,25)26/h3-6,11-14H,7-10H2,1-2H3,(H,21,24)(H2,19,25,26)
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n/an/a 4.12E+3n/an/an/an/a7.0n/a



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Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188232
PNG
(US9073941, 514)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1cc(C)cc(C)c1
Show InChI InChI=1S/C20H28N4O3S/c1-14(2)23-12-19(21-13-23)28(26,27)24-7-5-17(6-8-24)20(25)22-18-10-15(3)9-16(4)11-18/h9-14,17H,5-8H2,1-4H3,(H,22,25)
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n/an/a 2.67E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188233
PNG
(US9073941, 515)
Show SMILES CSc1cccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cn(cn2)C(C)C)c1
Show InChI InChI=1S/C19H26N4O3S2/c1-14(2)22-12-18(20-13-22)28(25,26)23-9-7-15(8-10-23)19(24)21-16-5-4-6-17(11-16)27-3/h4-6,11-15H,7-10H2,1-3H3,(H,21,24)
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n/an/a 4.81E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188235
PNG
(US9073941, 517)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1cccc(F)c1
Show InChI InChI=1S/C18H23FN4O3S/c1-13(2)22-11-17(20-12-22)27(25,26)23-8-6-14(7-9-23)18(24)21-16-5-3-4-15(19)10-16/h3-5,10-14H,6-9H2,1-2H3,(H,21,24)
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n/an/a 3.61E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188236
PNG
(US9073941, 518)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C18H23ClN4O3S/c1-13(2)22-11-17(20-12-22)27(25,26)23-8-6-14(7-9-23)18(24)21-16-5-3-4-15(19)10-16/h3-5,10-14H,6-9H2,1-2H3,(H,21,24)
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n/an/a 3.83E+3n/an/an/an/a7.0n/a



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US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188237
PNG
(US9073941, 519)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C18H23BrN4O3S/c1-13(2)22-11-17(20-12-22)27(25,26)23-8-6-14(7-9-23)18(24)21-16-5-3-4-15(19)10-16/h3-5,10-14H,6-9H2,1-2H3,(H,21,24)
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n/an/a 2.76E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188238
PNG
(US9073941, 520)
Show SMILES CCOc1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cn(cn2)C(C)C)cc1
Show InChI InChI=1S/C20H28N4O4S/c1-4-28-18-7-5-17(6-8-18)22-20(25)16-9-11-24(12-10-16)29(26,27)19-13-23(14-21-19)15(2)3/h5-8,13-16H,4,9-12H2,1-3H3,(H,22,25)
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n/an/a 2.17E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188239
PNG
(US9073941, 521)
Show SMILES COc1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cn(cn2)C(C)C)cc1
Show InChI InChI=1S/C19H26N4O4S/c1-14(2)22-12-18(20-13-22)28(25,26)23-10-8-15(9-11-23)19(24)21-16-4-6-17(27-3)7-5-16/h4-7,12-15H,8-11H2,1-3H3,(H,21,24)
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n/an/a 2.31E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188240
PNG
(US9073941, 522)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C18H23ClN4O3S/c1-13(2)22-11-17(20-12-22)27(25,26)23-9-7-14(8-10-23)18(24)21-16-5-3-15(19)4-6-16/h3-6,11-14H,7-10H2,1-2H3,(H,21,24)
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n/an/a 2.94E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188242
PNG
(US9073941, 524)
Show SMILES CC(C)n1cnc(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1ccccc1F
Show InChI InChI=1S/C18H23FN4O3S/c1-13(2)22-11-17(20-12-22)27(25,26)23-9-7-14(8-10-23)18(24)21-16-6-4-3-5-15(16)19/h3-6,11-14H,7-10H2,1-2H3,(H,21,24)
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n/an/a 2.67E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188243
PNG
(US9073941, 525)
Show SMILES CCOC(=O)c1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cn(cn2)C(C)C)cc1
Show InChI InChI=1S/C21H28N4O5S/c1-4-30-21(27)17-5-7-18(8-6-17)23-20(26)16-9-11-25(12-10-16)31(28,29)19-13-24(14-22-19)15(2)3/h5-8,13-16H,4,9-12H2,1-3H3,(H,23,26)
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US Patent
n/an/a 2.44E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair
Lipoamide Dehydrogenase (Lpd)


(Mycobacterium tuberculosis)
BDBM188229
PNG
(US9073941, 511)
Show SMILES CCc1cccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2cn(cn2)C(C)C)c1
Show InChI InChI=1S/C20H28N4O3S/c1-4-16-6-5-7-18(12-16)22-20(25)17-8-10-24(11-9-17)28(26,27)19-13-23(14-21-19)15(2)3/h5-7,12-15,17H,4,8-11H2,1-3H3,(H,22,25)
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n/an/a 2.55E+3n/an/an/an/a7.0n/a



Academia Sinica

US Patent


Assay Description
The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...


US Patent US9073941 (2015)


BindingDB Entry DOI: 10.7270/Q2HX1BGC
More data for this
Ligand-Target Pair