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83 similar compounds to monomer 21278

Compile data set for download or QSAR
Wt: 555.2
BDBM21279
Purchase
Wt: 522.4
BDBM87019
Wt: 381.2
BDBM50074308
Wt: 429.3
BDBM50074309
Wt: 444.3
BDBM50074310
Wt: 555.2
BDBM50074311
Wt: 508.2
BDBM50074314
Purchase
Wt: 444.3
BDBM50074315
Wt: 522.2
BDBM50074316
Wt: 474.3
BDBM50074317
Wt: 474.3
BDBM50074319
Wt: 510.2
BDBM50074321
Wt: 429.3
BDBM50074324
Wt: 494.2
BDBM50110936
Wt: 499.4
BDBM50110941
Displayed 1 to 15 (of 83 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 61 hits for monomerid = 21279,87019,50074308,50074309,50074310,50074311,50074314,50074315,50074316,50074317,50074319,50074321,50074324,50110936,50110941   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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0.600n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by ChEMBL


Assay Description
Binding affinity was determined by using a competition assay with [125 I]- AM251 against rat cannabinoid receptor 1


J Med Chem 46: 642-5 (2003)


Article DOI: 10.1021/jm020157x
BindingDB Entry DOI: 10.7270/Q27M079X
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50110941
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-(4-pentyl-pheny...)
Show SMILES CCCCCc1ccc(cc1)-c1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C27H32Cl2N4O/c1-3-4-6-9-20-10-12-21(13-11-20)26-19(2)25(27(34)31-32-16-7-5-8-17-32)30-33(26)24-15-14-22(28)18-23(24)29/h10-15,18H,3-9,16-17H2,1-2H3,(H,31,34)
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1n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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2.30n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK cells


Bioorg Med Chem 17: 5549-64 (2009)


Article DOI: 10.1016/j.bmc.2009.06.027
BindingDB Entry DOI: 10.7270/Q2XK8GHD
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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2.30n/an/an/an/an/an/an/an/a



University of Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK cells


Bioorg Med Chem 16: 7510-5 (2008)


Article DOI: 10.1016/j.bmc.2008.06.001
BindingDB Entry DOI: 10.7270/Q2C53MSN
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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2.30n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55,940 from recombinant human CB1 receptor transfected in HEK cells


Eur J Med Chem 45: 5878-86 (2010)


Article DOI: 10.1016/j.ejmech.2010.09.053
BindingDB Entry DOI: 10.7270/Q22Z15T3
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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2.30n/an/an/an/an/an/an/an/a



Sapienza University of Rome



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1560-76 (2008)


Article DOI: 10.1021/jm070566z
BindingDB Entry DOI: 10.7270/Q2GX48V9
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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3n/an/an/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor


Bioorg Med Chem Lett 17: 3978-82 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.087
BindingDB Entry DOI: 10.7270/Q2FN15XR
More data for this
Ligand-Target Pair
CNR1


(Saccharomyces cerevisiae)
BDBM87019
PNG
(1-(2,4-dichlorophenyl)-4-(hydroxymethyl)-N-(piperi...)
Show SMILES OCc1c(nn(c1-c1ccc(cc1)-c1cccnc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C27H25Cl2N5O2/c28-21-10-11-24(23(29)15-21)34-26(19-8-6-18(7-9-19)20-5-4-12-30-16-20)22(17-35)25(31-34)27(36)32-33-13-2-1-3-14-33/h4-12,15-16,35H,1-3,13-14,17H2,(H,32,36)
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5.80n/an/an/an/an/an/an/an/a



CNS Biological Research

Curated by PDSP Ki Database




J Med Chem 51: 2439-46 (2008)


Article DOI: 10.1021/jm701519h
BindingDB Entry DOI: 10.7270/Q22R3Q7S
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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6n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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7.49n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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7.49n/an/an/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Binding affinity to cannabinoid CB1 receptor


J Med Chem 53: 4332-53 (2010)


Article DOI: 10.1021/jm9018756
BindingDB Entry DOI: 10.7270/Q21R6QPF
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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7.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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7.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074316
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCCC1
Show InChI InChI=1S/C23H23BrCl2N4O/c1-15-21(23(31)28-29-12-4-2-3-5-13-29)27-30(20-11-10-18(25)14-19(20)26)22(15)16-6-8-17(24)9-7-16/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)
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7.85n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074316
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCCC1
Show InChI InChI=1S/C23H23BrCl2N4O/c1-15-21(23(31)28-29-12-4-2-3-5-13-29)27-30(20-11-10-18(25)14-19(20)26)22(15)16-6-8-17(24)9-7-16/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)
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7.85n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074314
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21BrCl2N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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16.8n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074314
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21BrCl2N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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16.8n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50110936
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCC1
Show InChI InChI=1S/C21H19BrCl2N4O/c1-13-19(21(29)26-27-10-2-3-11-27)25-28(18-9-8-16(23)12-17(18)24)20(13)14-4-6-15(22)7-5-14/h4-9,12H,2-3,10-11H2,1H3,(H,26,29)
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17.1n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074321
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCOCC1
Show InChI InChI=1S/C21H19BrCl2N4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-6-16(23)12-17(18)24)20(13)14-2-4-15(22)5-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
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19n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074311
PNG
(1-(2,4-Dichloro-phenyl)-5-(2-iodo-phenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccccc1I)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-5-2-6-12-28)26-29(19-10-9-15(23)13-17(19)24)21(14)16-7-3-4-8-18(16)25/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,27,30)
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53.8n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074321
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCOCC1
Show InChI InChI=1S/C21H19BrCl2N4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-6-16(23)12-17(18)24)20(13)14-2-4-15(22)5-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
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53.9n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074324
PNG
(1,5-Bis-(4-chloro-phenyl)-4-methyl-1H-pyrazole-3-c...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-13-3-2-4-14-27)25-28(19-11-9-18(24)10-12-19)21(15)16-5-7-17(23)8-6-16/h5-12H,2-4,13-14H2,1H3,(H,26,29)
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55n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074319
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl...)
Show SMILES Cc1c(nn(c1-c1ccc(cc1)[N+]([O-])=O)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2N5O3/c1-14-20(22(30)26-27-11-3-2-4-12-27)25-28(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(9-6-15)29(31)32/h5-10,13H,2-4,11-12H2,1H3,(H,26,30)
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57.5n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074324
PNG
(1,5-Bis-(4-chloro-phenyl)-4-methyl-1H-pyrazole-3-c...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-13-3-2-4-14-27)25-28(19-11-9-18(24)10-12-19)21(15)16-5-7-17(23)8-6-16/h5-12H,2-4,13-14H2,1H3,(H,26,29)
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60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074324
PNG
(1,5-Bis-(4-chloro-phenyl)-4-methyl-1H-pyrazole-3-c...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-13-3-2-4-14-27)25-28(19-11-9-18(24)10-12-19)21(15)16-5-7-17(23)8-6-16/h5-12H,2-4,13-14H2,1H3,(H,26,29)
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60n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074324
PNG
(1,5-Bis-(4-chloro-phenyl)-4-methyl-1H-pyrazole-3-c...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-13-3-2-4-14-27)25-28(19-11-9-18(24)10-12-19)21(15)16-5-7-17(23)8-6-16/h5-12H,2-4,13-14H2,1H3,(H,26,29)
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60.4n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074314
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21BrCl2N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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77n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074314
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21BrCl2N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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77n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074310
PNG
(5-(4-Amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(N)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H23Cl2N5O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12,25H2,1H3,(H,27,30)
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81n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074310
PNG
(5-(4-Amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(N)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H23Cl2N5O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12,25H2,1H3,(H,27,30)
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81.5n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074310
PNG
(5-(4-Amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(N)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H23Cl2N5O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12,25H2,1H3,(H,27,30)
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82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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110n/an/an/an/an/an/an/an/a



University of Salerno

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cells


Bioorg Med Chem 16: 7510-5 (2008)


Article DOI: 10.1016/j.bmc.2008.06.001
BindingDB Entry DOI: 10.7270/Q2C53MSN
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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112n/an/an/an/an/an/an/an/a



Sapienza University of Rome



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1560-76 (2008)


Article DOI: 10.1021/jm070566z
BindingDB Entry DOI: 10.7270/Q2GX48V9
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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112n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK cells


Bioorg Med Chem 17: 5549-64 (2009)


Article DOI: 10.1016/j.bmc.2009.06.027
BindingDB Entry DOI: 10.7270/Q2XK8GHD
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21279
PNG
(1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N...)
Show SMILES Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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112n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55,940 from recombinant human CB2 receptor transfected in HEK cells


Eur J Med Chem 45: 5878-86 (2010)


Article DOI: 10.1016/j.ejmech.2010.09.053
BindingDB Entry DOI: 10.7270/Q22Z15T3
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074309
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-12-6-3-7-13-27)25-28(19-11-10-17(23)14-18(19)24)21(15)16-8-4-2-5-9-16/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,26,29)
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123n/an/an/an/an/an/an/an/a



University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of [3H]-CP-55,940 binding to cannabinoid receptor 1 in rat brain membranes.


J Med Chem 45: 1447-59 (2002)


Article DOI: 10.1021/jm010267o
BindingDB Entry DOI: 10.7270/Q2222T3Z
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074309
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-12-6-3-7-13-27)25-28(19-11-10-17(23)14-18(19)24)21(15)16-8-4-2-5-9-16/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,26,29)
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123n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074309
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-12-6-3-7-13-27)25-28(19-11-10-17(23)14-18(19)24)21(15)16-8-4-2-5-9-16/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,26,29)
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123n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50074309
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-12-6-3-7-13-27)25-28(19-11-10-17(23)14-18(19)24)21(15)16-8-4-2-5-9-16/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,26,29)
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123n/an/an/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at CB1 receptor (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074308
PNG
(1-(2,4-Dichloro-phenyl)-5-ethyl-4-methyl-1H-pyrazo...)
Show SMILES CCc1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C18H22Cl2N4O/c1-3-15-12(2)17(18(25)22-23-9-5-4-6-10-23)21-24(15)16-8-7-13(19)11-14(16)20/h7-8,11H,3-6,9-10H2,1-2H3,(H,22,25)
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183n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074316
PNG
(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCCC1
Show InChI InChI=1S/C23H23BrCl2N4O/c1-15-21(23(31)28-29-12-4-2-3-5-13-29)27-30(20-11-10-18(25)14-19(20)26)22(15)16-6-8-17(24)9-7-16/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)
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215n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074309
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Show SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-12-6-3-7-13-27)25-28(19-11-10-17(23)14-18(19)24)21(15)16-8-4-2-5-9-16/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,26,29)
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217n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074319
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl...)
Show SMILES Cc1c(nn(c1-c1ccc(cc1)[N+]([O-])=O)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2N5O3/c1-14-20(22(30)26-27-11-3-2-4-12-27)25-28(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(9-6-15)29(31)32/h5-10,13H,2-4,11-12H2,1H3,(H,26,30)
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252n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074317
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-(2-nitro-phenyl...)
Show SMILES Cc1c(nn(c1-c1ccccc1[N+]([O-])=O)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2N5O3/c1-14-20(22(30)26-27-11-5-2-6-12-27)25-28(19-10-9-15(23)13-17(19)24)21(14)16-7-3-4-8-18(16)29(31)32/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,26,30)
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255n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50074315
PNG
(5-(2-Amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccccc1N)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H23Cl2N5O/c1-14-20(22(30)27-28-11-5-2-6-12-28)26-29(19-10-9-15(23)13-17(19)24)21(14)16-7-3-4-8-18(16)25/h3-4,7-10,13H,2,5-6,11-12,25H2,1H3,(H,27,30)
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346n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 1 in rat forebrain


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074311
PNG
(1-(2,4-Dichloro-phenyl)-5-(2-iodo-phenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccccc1I)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-5-2-6-12-28)26-29(19-10-9-15(23)13-17(19)24)21(14)16-7-3-4-8-18(16)25/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,27,30)
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577n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074317
PNG
(1-(2,4-Dichloro-phenyl)-4-methyl-5-(2-nitro-phenyl...)
Show SMILES Cc1c(nn(c1-c1ccccc1[N+]([O-])=O)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl2N5O3/c1-14-20(22(30)26-27-11-5-2-6-12-27)25-28(19-10-9-15(23)13-17(19)24)21(14)16-7-3-4-8-18(16)29(31)32/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,26,30)
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691n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074308
PNG
(1-(2,4-Dichloro-phenyl)-5-ethyl-4-methyl-1H-pyrazo...)
Show SMILES CCc1c(C)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C18H22Cl2N4O/c1-3-15-12(2)17(18(25)22-23-9-5-4-6-10-23)21-24(15)16-8-7-13(19)11-14(16)20/h7-8,11H,3-6,9-10H2,1-2H3,(H,22,25)
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744n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074324
PNG
(1,5-Bis-(4-chloro-phenyl)-4-methyl-1H-pyrazole-3-c...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H22Cl2N4O/c1-15-20(22(29)26-27-13-3-2-4-14-27)25-28(19-11-9-18(24)10-12-19)21(15)16-5-7-17(23)8-6-16/h5-12H,2-4,13-14H2,1H3,(H,26,29)
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836n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50074315
PNG
(5-(2-Amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methy...)
Show SMILES Cc1c(nn(c1-c1ccccc1N)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H23Cl2N5O/c1-14-20(22(30)27-28-11-5-2-6-12-28)26-29(19-10-9-15(23)13-17(19)24)21(14)16-7-3-4-8-18(16)25/h3-4,7-10,13H,2,5-6,11-12,25H2,1H3,(H,27,30)
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931n/an/an/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Binding affinity against Cannabinoid receptor 2 in mouse spleen


J Med Chem 42: 769-76 (1999)


Article DOI: 10.1021/jm980363y
BindingDB Entry DOI: 10.7270/Q2FJ2FZV
More data for this
Ligand-Target Pair
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