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1 similar compounds to monomer 22080

Compile data set for download or QSAR
Wt: 320.3
BDBM22077

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22077   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin B-Like Cysteine Protease (TbcatB)


(Trypanosoma brucei)
BDBM22077
PNG
(9-butyl-6-{[(4-methylphenyl)methyl]amino}-9H-purin...)
Show SMILES CCCCn1cnc2c(NCc3ccc(C)cc3)nc(nc12)C#N
Show InChI InChI=1S/C18H20N6/c1-3-4-9-24-12-21-16-17(22-15(10-19)23-18(16)24)20-11-14-7-5-13(2)6-8-14/h5-8,12H,3-4,9,11H2,1-2H3,(H,20,22,23)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/a25



University of California at San Francisco



Assay Description
Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...


J Med Chem 51: 545-52 (2008)


Article DOI: 10.1021/jm070760l
BindingDB Entry DOI: 10.7270/Q2V40SH0
More data for this
Ligand-Target Pair