Displayed 1 to 15 (of 21 total ) | Next | Last >> |
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 0.0700 | -13.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Purified MTAN activity in MTAN enzyme inhibition assay | Nat Chem Biol 5: 251-7 (2009) Article DOI: 10.1038/nchembio.153 BindingDB Entry DOI: 10.7270/Q28C9TM9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (docked) | ||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50170089![]() (1-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-ylmethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human MTAP as equilibrium dissociation constant | J Med Chem 48: 4679-89 (2005) Article DOI: 10.1021/jm050269z BindingDB Entry DOI: 10.7270/Q2FJ2HKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM36436![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.208 | -13.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Purified MTAN activity in MTAN enzyme inhibition assay | Nat Chem Biol 5: 251-7 (2009) Article DOI: 10.1038/nchembio.153 BindingDB Entry DOI: 10.7270/Q28C9TM9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326399![]() ((+/-)-trans-4-Butyl-1-[(9-deazaadenin-9-yl)methyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human MTAP as equilibrium dissociation constant | J Med Chem 48: 4679-89 (2005) Article DOI: 10.1021/jm050269z BindingDB Entry DOI: 10.7270/Q2FJ2HKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326398![]() ((+/-)-trans-1-[(9-Deazaadenin-9-yl)methyl]-4-ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326399![]() ((+/-)-trans-4-Butyl-1-[(9-deazaadenin-9-yl)methyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM22110![]() (Azetidine based compound, 43 | [1-({4-amino-5H-pyr...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.840 | -12.2 | n/a | n/a | n/a | n/a | n/a | 7.0 | 22 |
Industrial Research Limited | Assay Description Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293... | J Med Chem 51: 948-56 (2008) Article DOI: 10.1021/jm701265n BindingDB Entry DOI: 10.7270/Q2QC01T3 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (docked) | ||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human MTAP as initial dissociation constant | J Med Chem 48: 4679-89 (2005) Article DOI: 10.1021/jm050269z BindingDB Entry DOI: 10.7270/Q2FJ2HKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50170089![]() (1-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-ylmethyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human MTAP as initial dissociation constant | J Med Chem 48: 4679-89 (2005) Article DOI: 10.1021/jm050269z BindingDB Entry DOI: 10.7270/Q2FJ2HKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326400![]() ((+/-)-trans-1-[(9-Deazaadenin-9-yl)methyl]-3-hydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326407![]() ((+/-)-trans-4-Allyl-1-[(9-deazaadenin-9-yl)methyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326398![]() ((+/-)-trans-1-[(9-Deazaadenin-9-yl)methyl]-4-ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326406![]() ((+/-)-trans-1-[(9-Deazaadenin-9-yl)methyl]-3-hydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326404![]() ((+/-)-trans-4-(Cyclohexylmethyl)-1-[(9-deaza-adeni...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326401![]() ((+/-)-trans-1-[(9-Deazaadenin-9-yl)methyl]-3-hydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326408![]() ((+/-)-trans-1-[(9-Deazaadenin-9-yl)methyl]-4-ethyn...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM50326411![]() ((+/-)-Benzyl cis-3-(Benzoyloxy)-4-ethylpyrrolidine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of His-tagged human MTAP | J Med Chem 53: 6730-46 (2010) Article DOI: 10.1021/jm100898v BindingDB Entry DOI: 10.7270/Q22R3RWQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM22110![]() (Azetidine based compound, 43 | [1-({4-amino-5H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 140 | -9.25 | n/a | n/a | n/a | n/a | n/a | 7.0 | 22 |
Industrial Research Limited | Assay Description Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293... | J Med Chem 51: 948-56 (2008) Article DOI: 10.1021/jm701265n BindingDB Entry DOI: 10.7270/Q2QC01T3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Streptococcus pneumoniae) | BDBM22110![]() (Azetidine based compound, 43 | [1-({4-amino-5H-pyr...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | 150 | -9.21 | n/a | n/a | n/a | n/a | n/a | 7.0 | 22 |
Industrial Research Limited | Assay Description Enzyme activity was monitored by absorbance change in the xanthine oxidase coupled assay, which measures the formation of 2,8-dihydroxyadenine at 293... | J Med Chem 51: 948-56 (2008) Article DOI: 10.1021/jm701265n BindingDB Entry DOI: 10.7270/Q2QC01T3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Streptococcus pneumoniae) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB KEGG B.MOAD GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.0100 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Helicobacter pylori) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Helicobacter pylori) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.515 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Neisseria meningitidis) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0210 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Neisseria meningitidis) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0240 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Neisseria meningitidis) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0460 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Streptococcus pneumoniae) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Streptococcus pneumoniae) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.0000470 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.000460 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.000950 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (docked) | ||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Staphylococcus aureus) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 8 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Staphylococcus aureus) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.841 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Staphylococcus aureus) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Klebsiella pneumoniae) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Helicobacter pylori) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.570 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Klebsiella pneumoniae) | BDBM36435![]() ((3R,4S)-1-[(9-Deaza-adenin-9-yl)methyl]-4-ethylthi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Klebsiella pneumoniae) | BDBM36497![]() (CHEMBL191436 | DADMe-ImmA-Bn) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |