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10 molecules are shown

Wt: 455.3
BDBM23570
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Wt: 452.5
BDBM23572
Wt: 469.3
BDBM23573
Wt: 406.4
BDBM23574
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Wt: 394.4
BDBM23575
Wt: 459.5
BDBM23576
Wt: 468.5
BDBM23577
Wt: 474.5
BDBM23578
Wt: 412.2
BDBM23581
Wt: 428.2
BDBM23586

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 23570,23572,23573,23574,23575,23576,23577,23578,23581,23586   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23570
PNG
(2-{[4-bromo-3-(diethylsulfamoyl)benzene]amido}benz...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1Br)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C18H19BrN2O5S/c1-3-21(4-2)27(25,26)16-11-12(9-10-14(16)19)17(22)20-15-8-6-5-7-13(15)18(23)24/h5-11H,3-4H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 1.60E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23577
PNG
(2-{[3-(diethylsulfamoyl)-4-phenoxybenzene]amido}be...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1Oc1ccccc1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C24H24N2O6S/c1-3-26(4-2)33(30,31)22-16-17(14-15-21(22)32-18-10-6-5-7-11-18)23(27)25-20-13-9-8-12-19(20)24(28)29/h5-16H,3-4H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 6.10E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23573
PNG
(2-{[4-bromo-3-(diethylsulfamoyl)-5-methylbenzene]a...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(cc(C)c1Br)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C19H21BrN2O5S/c1-4-22(5-2)28(26,27)16-11-13(10-12(3)17(16)20)18(23)21-15-9-7-6-8-14(15)19(24)25/h6-11H,4-5H2,1-3H3,(H,21,23)(H,24,25)
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n/an/a 1.60E+5n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23574
PNG
(2-{[3-(diethylsulfamoyl)-4-methoxybenzene]amido}be...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1OC)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C19H22N2O6S/c1-4-21(5-2)28(25,26)17-12-13(10-11-16(17)27-3)18(22)20-15-9-7-6-8-14(15)19(23)24/h6-12H,4-5H2,1-3H3,(H,20,22)(H,23,24)
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n/an/a 1.14E+4n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23575
PNG
(2-{[3-(diethylsulfamoyl)-4-fluorobenzene]amido}ben...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1F)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C18H19FN2O5S/c1-3-21(4-2)27(25,26)16-11-12(9-10-14(16)19)17(22)20-15-8-6-5-7-13(15)18(23)24/h5-11H,3-4H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 8.40E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23576
PNG
(2-{[3-(diethylsulfamoyl)-4-(piperidin-1-yl)benzene...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1N1CCCCC1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C23H29N3O5S/c1-3-26(4-2)32(30,31)21-16-17(12-13-20(21)25-14-8-5-9-15-25)22(27)24-19-11-7-6-10-18(19)23(28)29/h6-7,10-13,16H,3-5,8-9,14-15H2,1-2H3,(H,24,27)(H,28,29)
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n/an/a 2.20E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23577
PNG
(2-{[3-(diethylsulfamoyl)-4-phenoxybenzene]amido}be...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1Oc1ccccc1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C24H24N2O6S/c1-3-26(4-2)33(30,31)22-16-17(14-15-21(22)32-18-10-6-5-7-11-18)23(27)25-20-13-9-8-12-19(20)24(28)29/h5-16H,3-4H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 6.10E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23578
PNG
(2-{[4-(cyclopentylmethoxy)-3-(diethylsulfamoyl)ben...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1OCC1CCCC1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C24H30N2O6S/c1-3-26(4-2)33(30,31)22-15-18(13-14-21(22)32-16-17-9-5-6-10-17)23(27)25-20-12-8-7-11-19(20)24(28)29/h7-8,11-15,17H,3-6,9-10,16H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 2.10E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23581
PNG
((3-Phenoxybenzoylamino)benzoic acid deriv., 23b | ...)
Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1
Show InChI InChI=1S/C20H14BrNO4/c21-16-11-10-13(12-18(16)26-14-6-2-1-3-7-14)19(23)22-17-9-5-4-8-15(17)20(24)25/h1-12H,(H,22,23)(H,24,25)
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n/an/a 1.10E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23586
PNG
((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Show SMILES OC(=O)c1c(O)cccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1
Show InChI InChI=1S/C20H14BrNO5/c21-14-10-9-12(11-17(14)27-13-5-2-1-3-6-13)19(24)22-15-7-4-8-16(23)18(15)20(25)26/h1-11,23H,(H,22,24)(H,25,26)
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n/an/a 62n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Streptococcus pyogenes)
BDBM23586
PNG
((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Show SMILES OC(=O)c1c(O)cccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1
Show InChI InChI=1S/C20H14BrNO5/c21-14-10-9-12(11-17(14)27-13-5-2-1-3-6-13)19(24)22-15-7-4-8-16(23)18(15)20(25)26/h1-11,23H,(H,22,24)(H,25,26)
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n/an/a 34n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
beta-Ketoacyl-ACP Synthase III (FabH)


(Staphylococcus aureus)
BDBM23586
PNG
((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Show SMILES OC(=O)c1c(O)cccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1
Show InChI InChI=1S/C20H14BrNO5/c21-14-10-9-12(11-17(14)27-13-5-2-1-3-6-13)19(24)22-15-7-4-8-16(23)18(15)20(25)26/h1-11,23H,(H,22,24)(H,25,26)
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n/an/a 1.23E+4n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
beta-Ketoacyl-ACP Synthase III (FabH)


(Haemophilus influenzae)
BDBM23586
PNG
((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Show SMILES OC(=O)c1c(O)cccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1
Show InChI InChI=1S/C20H14BrNO5/c21-14-10-9-12(11-17(14)27-13-5-2-1-3-6-13)19(24)22-15-7-4-8-16(23)18(15)20(25)26/h1-11,23H,(H,22,24)(H,25,26)
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n/an/a 2.00E+4n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23570
PNG
(2-{[4-bromo-3-(diethylsulfamoyl)benzene]amido}benz...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1Br)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C18H19BrN2O5S/c1-3-21(4-2)27(25,26)16-11-12(9-10-14(16)19)17(22)20-15-8-6-5-7-13(15)18(23)24/h5-11H,3-4H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23572
PNG
(2-{[3-(diethylsulfamoyl)-4-phenylbenzene]amido}ben...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1-c1ccccc1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C24H24N2O5S/c1-3-26(4-2)32(30,31)22-16-18(14-15-19(22)17-10-6-5-7-11-17)23(27)25-21-13-9-8-12-20(21)24(28)29/h5-16H,3-4H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23575
PNG
(2-{[3-(diethylsulfamoyl)-4-fluorobenzene]amido}ben...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1F)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C18H19FN2O5S/c1-3-21(4-2)27(25,26)16-11-12(9-10-14(16)19)17(22)20-15-8-6-5-7-13(15)18(23)24/h5-11H,3-4H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 8.39E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23576
PNG
(2-{[3-(diethylsulfamoyl)-4-(piperidin-1-yl)benzene...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1N1CCCCC1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C23H29N3O5S/c1-3-26(4-2)32(30,31)21-16-17(12-13-20(21)25-14-8-5-9-15-25)22(27)24-19-11-7-6-10-18(19)23(28)29/h6-7,10-13,16H,3-5,8-9,14-15H2,1-2H3,(H,24,27)(H,28,29)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23578
PNG
(2-{[4-(cyclopentylmethoxy)-3-(diethylsulfamoyl)ben...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1OCC1CCCC1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C24H30N2O6S/c1-3-26(4-2)33(30,31)22-15-18(13-14-21(22)32-16-17-9-5-6-10-17)23(27)25-20-12-8-7-11-19(20)24(28)29/h7-8,11-15,17H,3-6,9-10,16H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 2.10E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23581
PNG
((3-Phenoxybenzoylamino)benzoic acid deriv., 23b | ...)
Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1
Show InChI InChI=1S/C20H14BrNO4/c21-16-11-10-13(12-18(16)26-14-6-2-1-3-7-14)19(23)22-17-9-5-4-8-15(17)20(24)25/h1-12H,(H,22,23)(H,24,25)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23573
PNG
(2-{[4-bromo-3-(diethylsulfamoyl)-5-methylbenzene]a...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(cc(C)c1Br)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C19H21BrN2O5S/c1-4-22(5-2)28(26,27)16-11-13(10-12(3)17(16)20)18(23)21-15-9-7-6-8-14(15)19(24)25/h6-11H,4-5H2,1-3H3,(H,21,23)(H,24,25)
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n/an/a 1.60E+5n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23574
PNG
(2-{[3-(diethylsulfamoyl)-4-methoxybenzene]amido}be...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1OC)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C19H22N2O6S/c1-4-21(5-2)28(25,26)17-12-13(10-11-16(17)27-3)18(22)20-15-9-7-6-8-14(15)19(23)24/h6-12H,4-5H2,1-3H3,(H,20,22)(H,23,24)
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n/an/a 1.14E+4n/an/an/an/an/an/a



Shri G.S. Institute of Technology and Science

Curated by ChEMBL


Assay Description
Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assay


Eur J Med Chem 43: 1071-80 (2008)


Article DOI: 10.1016/j.ejmech.2007.06.018
BindingDB Entry DOI: 10.7270/Q2GQ700V
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
beta-Ketoacyl-ACP Synthase III (FabH)


(Enterococcus faecalis)
BDBM23572
PNG
(2-{[3-(diethylsulfamoyl)-4-phenylbenzene]amido}ben...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1-c1ccccc1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C24H24N2O5S/c1-3-26(4-2)32(30,31)22-16-18(14-15-19(22)17-10-6-5-7-11-17)23(27)25-21-13-9-8-12-20(21)24(28)29/h5-16H,3-4H2,1-2H3,(H,25,27)(H,28,29)
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n/an/a 1.60E+3n/an/an/an/a7.022



Quorex Pharmaceuticals Inc.



Assay Description
The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...


J Med Chem 48: 1596-609 (2005)


Article DOI: 10.1021/jm049141s
BindingDB Entry DOI: 10.7270/Q22B8W9H
More data for this
Ligand-Target Pair
3D
3D Structure (docked)