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50 similar compounds to monomer 23620

Wt: 560.7
BDBM23631
Purchase
Wt: 472.6
BDBM23632
Wt: 588.7
BDBM23633
Wt: 500.6
BDBM23634
Wt: 556.7
BDBM23635
Wt: 468.5
BDBM23636
Wt: 636.8
BDBM23637
Wt: 480.6
BDBM23641
Wt: 392.4
BDBM23642
Wt: 536.7
BDBM23643
Wt: 448.6
BDBM23644
Wt: 592.8
BDBM23645
Wt: 504.7
BDBM23646
Wt: 592.8
BDBM23647
Wt: 504.7
BDBM23648
Displayed 1 to 15 (of 50 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 23631,23632,23633,23634,23635,23636,23637,23641,23642,23643,23644,23645,23646,23647,23648   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23631
PNG
(2-{[4,8-bis(azocan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Show SMILES OCCN(CCO)c1nc(N2CCCCCCC2)c2nc(nc(N3CCCCCCC3)c2n1)N(CCO)CCO
Show InChI InChI=1S/C28H48N8O4/c37-19-15-35(16-20-38)27-30-24-23(25(31-27)33-11-7-3-1-4-8-12-33)29-28(36(17-21-39)18-22-40)32-26(24)34-13-9-5-2-6-10-14-34/h37-40H,1-22H2
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PubMed
0.490 -12.6 8.67n/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23633
PNG
(2-{[4,8-bis(azonan-1-yl)-6-[bis(2-hydroxyethyl)ami...)
Show SMILES OCCN(CCO)c1nc(N2CCCCCCCC2)c2nc(nc(N3CCCCCCCC3)c2n1)N(CCO)CCO
Show InChI InChI=1S/C30H52N8O4/c39-21-17-37(18-22-40)29-32-26-25(27(33-29)35-13-9-5-1-2-6-10-14-35)31-30(38(19-23-41)20-24-42)34-28(26)36-15-11-7-3-4-8-12-16-36/h39-42H,1-24H2
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0.770 -12.3 13.6n/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23632
PNG
(2-{[4,8-bis(azocan-1-yl)-6-[(2-hydroxyethyl)amino]...)
Show SMILES OCCNc1nc(N2CCCCCCC2)c2nc(NCCO)nc(N3CCCCCCC3)c2n1
Show InChI InChI=1S/C24H40N8O2/c33-17-11-25-23-28-20-19(21(29-23)31-13-7-3-1-4-8-14-31)27-24(26-12-18-34)30-22(20)32-15-9-5-2-6-10-16-32/h33-34H,1-18H2,(H,25,28,29)(H,26,27,30)
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21.2 -10.4 375n/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23634
PNG
(2-{[4,8-bis(azonan-1-yl)-6-[(2-hydroxyethyl)amino]...)
Show SMILES OCCNc1nc(N2CCCCCCCC2)c2nc(NCCO)nc(N3CCCCCCCC3)c2n1
Show InChI InChI=1S/C26H44N8O2/c35-19-13-27-25-30-22-21(23(31-25)33-15-9-5-1-2-6-10-16-33)29-26(28-14-20-36)32-24(22)34-17-11-7-3-4-8-12-18-34/h35-36H,1-20H2,(H,27,30,31)(H,28,29,32)
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38 -10.0 672n/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23635
PNG
(2-{[4,8-bis({8-azabicyclo[3.2.1]octan-8-yl})-6-[bi...)
Show SMILES OCCN(CCO)c1nc(N2C3CCC2CCC3)c2nc(nc(N3C4CCC3CCC4)c2n1)N(CCO)CCO
Show InChI InChI=1S/C28H44N8O4/c37-15-11-33(12-16-38)27-30-24-23(25(31-27)35-19-3-1-4-20(35)8-7-19)29-28(34(13-17-39)14-18-40)32-26(24)36-21-5-2-6-22(36)10-9-21/h19-22,37-40H,1-18H2
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193 -9.06 3.42E+3n/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23641
PNG
(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(diethylam...)
Show SMILES CCN(CC)c1nc(nc2c(nc(nc12)N(CCO)CCO)N(CC)CC)N(CCO)CCO
Show InChI InChI=1S/C22H40N8O4/c1-5-27(6-2)19-17-18(24-21(25-19)29(9-13-31)10-14-32)20(28(7-3)8-4)26-22(23-17)30(11-15-33)12-16-34/h31-34H,5-16H2,1-4H3
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216 -8.99 3.83E+3n/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23637
PNG
(2-{[4,8-bis({4-azatricyclo[4.3.1.1^{3,8}]undecan-4...)
Show SMILES OCCN(CCO)c1nc(N2CC3CC4CC(C3)CC2C4)c2nc(nc(N3CC4CC5CC(C4)CC3C5)c2n1)N(CCO)CCO
Show InChI InChI=1S/C34H52N8O4/c43-5-1-39(2-6-44)33-35-29-30(31(37-33)41-19-25-11-21-9-22(12-25)16-27(41)15-21)36-34(40(3-7-45)4-8-46)38-32(29)42-20-26-13-23-10-24(14-26)18-28(42)17-23/h21-28,43-46H,1-20H2
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n/an/an/an/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23648
PNG
(2-({4,8-bis[bis(2-methylpropyl)amino]-6-[(2-hydrox...)
Show SMILES CC(C)CN(CC(C)C)c1nc(NCCO)nc2c(nc(NCCO)nc12)N(CC(C)C)CC(C)C
Show InChI InChI=1S/C26H48N8O2/c1-17(2)13-33(14-18(3)4)23-21-22(30-25(31-23)27-9-11-35)24(32-26(29-21)28-10-12-36)34(15-19(5)6)16-20(7)8/h17-20,35-36H,9-16H2,1-8H3,(H,27,30,31)(H,28,29,32)
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n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23642
PNG
(2-{[4,8-bis(diethylamino)-6-[(2-hydroxyethyl)amino...)
Show SMILES CCN(CC)c1nc(NCCO)nc2c(nc(NCCO)nc12)N(CC)CC
Show InChI InChI=1S/C18H32N8O2/c1-5-25(6-2)15-13-14(22-17(23-15)19-9-11-27)16(26(7-3)8-4)24-18(21-13)20-10-12-28/h27-28H,5-12H2,1-4H3,(H,19,22,23)(H,20,21,24)
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n/an/an/an/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23643
PNG
(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(dipropyla...)
Show SMILES CCCN(CCC)c1nc(nc2c(nc(nc12)N(CCO)CCO)N(CCC)CCC)N(CCO)CCO
Show InChI InChI=1S/C26H48N8O4/c1-5-9-31(10-6-2)23-21-22(28-25(29-23)33(13-17-35)14-18-36)24(32(11-7-3)12-8-4)30-26(27-21)34(15-19-37)16-20-38/h35-38H,5-20H2,1-4H3
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n/an/an/an/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23636
PNG
(2-{[4,8-bis({8-azabicyclo[3.2.1]octan-8-yl})-6-[(2...)
Show SMILES OCCNc1nc(N2C3CCC2CCC3)c2nc(NCCO)nc(N3C4CCC3CCC4)c2n1
Show InChI InChI=1S/C24H36N8O2/c33-13-11-25-23-28-20-19(21(29-23)31-15-3-1-4-16(31)8-7-15)27-24(26-12-14-34)30-22(20)32-17-5-2-6-18(32)10-9-17/h15-18,33-34H,1-14H2,(H,25,28,29)(H,26,27,30)
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n/an/an/an/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23645
PNG
(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(dibutylam...)
Show SMILES CCCCN(CCCC)c1nc(nc2c(nc(nc12)N(CCO)CCO)N(CCCC)CCCC)N(CCO)CCO
Show InChI InChI=1S/C30H56N8O4/c1-5-9-13-35(14-10-6-2)27-25-26(32-29(33-27)37(17-21-39)18-22-40)28(36(15-11-7-3)16-12-8-4)34-30(31-25)38(19-23-41)20-24-42/h39-42H,5-24H2,1-4H3
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n/an/an/an/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23646
PNG
(2-{[4,8-bis(dibutylamino)-6-[(2-hydroxyethyl)amino...)
Show SMILES CCCCN(CCCC)c1nc(NCCO)nc2c(nc(NCCO)nc12)N(CCCC)CCCC
Show InChI InChI=1S/C26H48N8O2/c1-5-9-15-33(16-10-6-2)23-21-22(30-25(31-23)27-13-19-35)24(32-26(29-21)28-14-20-36)34(17-11-7-3)18-12-8-4/h35-36H,5-20H2,1-4H3,(H,27,30,31)(H,28,29,32)
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n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23647
PNG
(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis[bis(2-met...)
Show SMILES CC(C)CN(CC(C)C)c1nc(nc2c(nc(nc12)N(CCO)CCO)N(CC(C)C)CC(C)C)N(CCO)CCO
Show InChI InChI=1S/C30H56N8O4/c1-21(2)17-37(18-22(3)4)27-25-26(32-29(33-27)35(9-13-39)10-14-40)28(38(19-23(5)6)20-24(7)8)34-30(31-25)36(11-15-41)12-16-42/h21-24,39-42H,9-20H2,1-8H3
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n/an/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair
Equilibrative Nucleoside Transporter 1 (ENT1)


(Homo sapiens (human))
BDBM23644
PNG
(2-{[4,8-bis(dipropylamino)-6-[(2-hydroxyethyl)amin...)
Show SMILES CCCN(CCC)c1nc(NCCO)nc2c(nc(NCCO)nc12)N(CCC)CCC
Show InChI InChI=1S/C22H40N8O2/c1-5-11-29(12-6-2)19-17-18(26-21(27-19)23-9-15-31)20(30(13-7-3)14-8-4)28-22(25-17)24-10-16-32/h31-32H,5-16H2,1-4H3,(H,23,26,27)(H,24,25,28)
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n/an/an/an/an/an/an/a7.422



University of Tennessee Health Science Center



Assay Description
The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...


J Med Chem 50: 3906-20 (2007)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2XK8CVN
More data for this
Ligand-Target Pair