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20 similar compounds to monomer 25558

Compile data set for download or QSAR
Wt: 331.3
BDBM25544
Wt: 345.3
BDBM25550
Wt: 370.4
BDBM25559
Wt: 370.4
BDBM29816
Wt: 414.4
BDBM29817
Wt: 414.4
BDBM29818
Wt: 414.4
BDBM29819
Wt: 384.4
BDBM29820
Wt: 439.5
BDBM29826
Wt: 384.4
BDBM50258384
Wt: 398.4
BDBM50258385
Wt: 384.4
BDBM50258386
Wt: 384.4
BDBM50258387
Wt: 398.4
BDBM50258796
Wt: 354.4
BDBM50258798
Displayed 1 to 15 (of 20 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 25544,25550,25559,29816,29817,29818,29819,29820,29826,50258384,50258385,50258386,50258387,50258796,50258798   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C theta type


(Homo sapiens (Human))
BDBM25544
PNG
(4-arylamino-3-pyridinecarbonitrile, 4b | 5-(3,4-di...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccccc1
Show InChI InChI=1S/C20H17N3O2/c1-24-18-9-8-14(10-19(18)25-2)17-13-22-12-15(11-21)20(17)23-16-6-4-3-5-7-16/h3-10,12-13H,1-2H3,(H,22,23)
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n/an/a 1.60E+3n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


J Med Chem 51: 5958-63 (2008)


Article DOI: 10.1021/jm800214a
BindingDB Entry DOI: 10.7270/Q21V5C8K
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50258384
PNG
(5-(3,4-dimethoxyphenyl)-4-(4-methyl-1H-indol-5-yla...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C
Show InChI InChI=1S/C23H20N4O2/c1-14-17-8-9-26-20(17)6-5-19(14)27-23-16(11-24)12-25-13-18(23)15-4-7-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)
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n/an/a 6.30n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM25559
PNG
(4-arylamino-3-pyridinecarbonitrile, 4q | 5-(3,4-di...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2cc[nH]c2c1
Show InChI InChI=1S/C22H18N4O2/c1-27-20-6-4-15(9-21(20)28-2)18-13-24-12-16(11-23)22(18)26-17-5-3-14-7-8-25-19(14)10-17/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 2.20E+3n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


J Med Chem 51: 5958-63 (2008)


Article DOI: 10.1021/jm800214a
BindingDB Entry DOI: 10.7270/Q21V5C8K
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM25559
PNG
(4-arylamino-3-pyridinecarbonitrile, 4q | 5-(3,4-di...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2cc[nH]c2c1
Show InChI InChI=1S/C22H18N4O2/c1-27-20-6-4-15(9-21(20)28-2)18-13-24-12-16(11-23)22(18)26-17-5-3-14-7-8-25-19(14)10-17/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 2.20E+3n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29816
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 1c...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12
Show InChI InChI=1S/C22H18N4O2/c1-27-20-7-6-14(10-21(20)28-2)17-13-24-12-15(11-23)22(17)26-19-5-3-4-18-16(19)8-9-25-18/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 13n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29817
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 7a)
Show SMILES COCCOc1cc(ccc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12
Show InChI InChI=1S/C24H22N4O3/c1-29-10-11-31-23-12-16(6-7-22(23)30-2)19-15-26-14-17(13-25)24(19)28-21-5-3-4-20-18(21)8-9-27-20/h3-9,12,14-15,27H,10-11H2,1-2H3,(H,26,28)
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n/an/a 63n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29818
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 7b)
Show SMILES COCCOc1cc(ccc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1
Show InChI InChI=1S/C24H22N4O3/c1-29-9-10-31-23-12-16(3-6-22(23)30-2)20-15-26-14-18(13-25)24(20)28-19-4-5-21-17(11-19)7-8-27-21/h3-8,11-12,14-15,27H,9-10H2,1-2H3,(H,26,28)
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n/an/a 320n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29819
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 7c)
Show SMILES COCCOc1cc(ccc1OC)-c1cncc(C#N)c1Nc1ccc2cc[nH]c2c1
Show InChI InChI=1S/C24H22N4O3/c1-29-9-10-31-23-11-17(4-6-22(23)30-2)20-15-26-14-18(13-25)24(20)28-19-5-3-16-7-8-27-21(16)12-19/h3-8,11-12,14-15,27H,9-10H2,1-2H3,(H,26,28)
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n/an/a 6.30E+3n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29820
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 7d)
Show SMILES COCCOc1cccc(c1)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12
Show InChI InChI=1S/C23H20N4O2/c1-28-10-11-29-18-5-2-4-16(12-18)20-15-25-14-17(13-24)23(20)27-22-7-3-6-21-19(22)8-9-26-21/h2-9,12,14-15,26H,10-11H2,1H3,(H,25,27)
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n/an/a 32n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29826
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 12...)
Show SMILES N#Cc1cncc(-c2cccc(OCCN3CCOCC3)c2)c1Nc1ccc2[nH]ccc2c1
Show InChI InChI=1S/C26H25N5O2/c27-16-21-17-28-18-24(26(21)30-22-4-5-25-20(14-22)6-7-29-25)19-2-1-3-23(15-19)33-13-10-31-8-11-32-12-9-31/h1-7,14-15,17-18,29H,8-13H2,(H,28,30)
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n/an/a 200n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


Bioorg Med Chem Lett 19: 2461-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.053
BindingDB Entry DOI: 10.7270/Q21R6NVV
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM29816
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 1c...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12
Show InChI InChI=1S/C22H18N4O2/c1-27-20-7-6-14(10-21(20)28-2)17-13-24-12-15(11-23)22(17)26-19-5-3-4-18-16(19)8-9-25-18/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 13n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM25559
PNG
(4-arylamino-3-pyridinecarbonitrile, 4q | 5-(3,4-di...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2cc[nH]c2c1
Show InChI InChI=1S/C22H18N4O2/c1-27-20-6-4-15(9-21(20)28-2)18-13-24-12-16(11-23)22(18)26-17-5-3-14-7-8-25-19(14)10-17/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 2.30E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50258385
PNG
(5-(3,4-dimethoxyphenyl)-4-(4-ethyl-1H-indol-5-ylam...)
Show SMILES CCc1c(Nc2c(cncc2-c2ccc(OC)c(OC)c2)C#N)ccc2[nH]ccc12
Show InChI InChI=1S/C24H22N4O2/c1-4-17-18-9-10-27-20(18)6-7-21(17)28-24-16(12-25)13-26-14-19(24)15-5-8-22(29-2)23(11-15)30-3/h5-11,13-14,27H,4H2,1-3H3,(H,26,28)
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n/an/a 55n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50258386
PNG
(5-(3,4-dimethoxyphenyl)-4-(7-methyl-1H-indol-5-yla...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc(C)c2[nH]ccc2c1
Show InChI InChI=1S/C23H20N4O2/c1-14-8-18(9-16-6-7-26-22(14)16)27-23-17(11-24)12-25-13-19(23)15-4-5-20(28-2)21(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)
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n/an/a 120n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50258387
PNG
(5-(3,4-dimethoxyphenyl)-4-(6-methyl-1H-indol-5-yla...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc2cc[nH]c2cc1C
Show InChI InChI=1S/C23H20N4O2/c1-14-8-20-16(6-7-26-20)9-19(14)27-23-17(11-24)12-25-13-18(23)15-4-5-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)
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n/an/a 11n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50258796
PNG
(5-(3,4-dimethoxyphenyl)-4-(1,4-dimethyl-1H-indol-5...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2n(C)ccc2c1C
Show InChI InChI=1S/C24H22N4O2/c1-15-18-9-10-28(2)21(18)7-6-20(15)27-24-17(12-25)13-26-14-19(24)16-5-8-22(29-3)23(11-16)30-4/h5-11,13-14H,1-4H3,(H,26,27)
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n/an/a 260n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM50258798
PNG
(5-(4-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...)
Show SMILES COc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C
Show InChI InChI=1S/C22H18N4O/c1-14-18-9-10-25-21(18)8-7-20(14)26-22-16(11-23)12-24-13-19(22)15-3-5-17(27-2)6-4-15/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 5.60n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCtheta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM29816
PNG
(4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 1c...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12
Show InChI InChI=1S/C22H18N4O2/c1-27-20-7-6-14(10-21(20)28-2)17-13-24-12-15(11-23)22(17)26-19-5-3-4-18-16(19)8-9-25-18/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 62n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCdelta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50258384
PNG
(5-(3,4-dimethoxyphenyl)-4-(4-methyl-1H-indol-5-yla...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C
Show InChI InChI=1S/C23H20N4O2/c1-14-17-8-9-26-20(17)6-5-19(14)27-23-16(11-24)12-25-13-18(23)15-4-7-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)
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n/an/a 81n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCdelta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50258385
PNG
(5-(3,4-dimethoxyphenyl)-4-(4-ethyl-1H-indol-5-ylam...)
Show SMILES CCc1c(Nc2c(cncc2-c2ccc(OC)c(OC)c2)C#N)ccc2[nH]ccc12
Show InChI InChI=1S/C24H22N4O2/c1-4-17-18-9-10-27-20(18)6-7-21(17)28-24-16(12-25)13-26-14-19(24)15-5-8-22(29-2)23(11-15)30-3/h5-11,13-14,27H,4H2,1-3H3,(H,26,28)
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n/an/a 980n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCdelta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50258387
PNG
(5-(3,4-dimethoxyphenyl)-4-(6-methyl-1H-indol-5-yla...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc2cc[nH]c2cc1C
Show InChI InChI=1S/C23H20N4O2/c1-14-8-20-16(6-7-26-20)9-19(14)27-23-17(11-24)12-25-13-18(23)15-4-5-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)
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n/an/a 280n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCdelta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50258796
PNG
(5-(3,4-dimethoxyphenyl)-4-(1,4-dimethyl-1H-indol-5...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2n(C)ccc2c1C
Show InChI InChI=1S/C24H22N4O2/c1-15-18-9-10-28(2)21(18)7-6-20(15)27-24-17(12-25)13-26-14-19(24)16-5-8-22(29-3)23(11-16)30-4/h5-11,13-14H,1-4H3,(H,26,27)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCdelta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C delta type


(Homo sapiens (Human))
BDBM50258798
PNG
(5-(4-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...)
Show SMILES COc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C
Show InChI InChI=1S/C22H18N4O/c1-14-18-9-10-25-21(18)8-7-20(14)26-22-16(11-23)12-24-13-19(22)15-3-5-17(27-2)6-4-15/h3-10,12-13,25H,1-2H3,(H,24,26)
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n/an/a 85n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of human PKCdelta by IMAP assay


Bioorg Med Chem Lett 19: 3623-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4
More data for this
Ligand-Target Pair
Protein kinase C theta type


(Homo sapiens (Human))
BDBM25550
PNG
(4-arylamino-3-pyridinecarbonitrile, 4h | 5-(3,4-di...)
Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc(C)cc1
Show InChI InChI=1S/C21H19N3O2/c1-14-4-7-17(8-5-14)24-21-16(11-22)12-23-13-18(21)15-6-9-19(25-2)20(10-15)26-3/h4-10,12-13H,1-3H3,(H,23,24)
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n/an/a 900n/an/an/an/a7.222



Wyeth Research



Assay Description
All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...


J Med Chem 51: 5958-63 (2008)


Article DOI: 10.1021/jm800214a
BindingDB Entry DOI: 10.7270/Q21V5C8K
More data for this
Ligand-Target Pair