BindingDB logo
myBDB logout

21 similar compounds to monomer 50176812

Compile data set for download or QSAR
Wt: 443.9
BDBM27580
Wt: 325.3
BDBM50052065
Wt: 343.4
BDBM50052045
Wt: 303.3
BDBM50052046
Wt: 315.3
BDBM50052048
Wt: 353.4
BDBM50052049
Wt: 353.4
BDBM50052051
Wt: 289.3
BDBM50052052
Wt: 329.3
BDBM50052055
Wt: 317.3
BDBM50052057
Wt: 325.3
BDBM50052060
Wt: 275.3
BDBM50052061
Wt: 317.3
BDBM50082057
Wt: 339.3
BDBM50082058
Wt: 321.3
BDBM50082059
Displayed 1 to 15 (of 21 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 27580,50052065,50052045,50052046,50052048,50052049,50052051,50052052,50052055,50052057,50052060,50052061,50082057,50082058,50082059   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
70n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against HIV-1 wild type reverse transcriptase (RT)


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082059
PNG
(5-Ethyl-5-(3-fluoro-phenyl)-6-oxa-10b-aza-benzo[e]...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(F)c1
Show InChI InChI=1S/C20H16FNO2/c1-2-20(14-7-5-8-15(21)13-14)19(23)17-10-6-12-22(17)16-9-3-4-11-18(16)24-20/h3-13H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
70n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution K103N


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution L100I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082059
PNG
(5-Ethyl-5-(3-fluoro-phenyl)-6-oxa-10b-aza-benzo[e]...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(F)c1
Show InChI InChI=1S/C20H16FNO2/c1-2-20(14-7-5-8-15(21)13-14)19(23)17-10-6-12-22(17)16-9-3-4-11-18(16)24-20/h3-13H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against HIV-1 wild type reverse transcriptase (RT)


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM27580
PNG
(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(COc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C27H22ClNO3/c1-2-27(20-14-12-19(13-15-20)18-31-22-8-5-7-21(28)17-22)26(30)24-10-6-16-29(24)23-9-3-4-11-25(23)32-27/h3-17H,2,18H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
100 -9.93n/an/an/an/an/a7.537



Universita di Siena



Assay Description
The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...


J Med Chem 52: 1224-8 (2009)


Article DOI: 10.1021/jm801395v
BindingDB Entry DOI: 10.7270/Q237772D
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082059
PNG
(5-Ethyl-5-(3-fluoro-phenyl)-6-oxa-10b-aza-benzo[e]...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(F)c1
Show InChI InChI=1S/C20H16FNO2/c1-2-20(14-7-5-8-15(21)13-14)19(23)17-10-6-12-22(17)16-9-3-4-11-18(16)24-20/h3-13H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
160n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution L100I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
190n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against HIV-1 wild type reverse transcriptase (RT)


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (L100I)


(Human immunodeficiency virus type 1)
BDBM27580
PNG
(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(COc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C27H22ClNO3/c1-2-27(20-14-12-19(13-15-20)18-31-22-8-5-7-21(28)17-22)26(30)24-10-6-16-29(24)23-9-3-4-11-25(23)32-27/h3-17H,2,18H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
250 -9.36n/an/an/an/an/a7.537



Universita di Siena



Assay Description
The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...


J Med Chem 52: 1224-8 (2009)


Article DOI: 10.1021/jm801395v
BindingDB Entry DOI: 10.7270/Q237772D
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
250n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution V106A


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (V179D)


(Human immunodeficiency virus type 1)
BDBM27580
PNG
(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(COc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C27H22ClNO3/c1-2-27(20-14-12-19(13-15-20)18-31-22-8-5-7-21(28)17-22)26(30)24-10-6-16-29(24)23-9-3-4-11-25(23)32-27/h3-17H,2,18H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
300n/an/an/an/an/an/an/an/a



Universita di Siena



Assay Description
The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...


J Med Chem 52: 1224-8 (2009)


Article DOI: 10.1021/jm801395v
BindingDB Entry DOI: 10.7270/Q237772D
More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (K103N)


(Human immunodeficiency virus type 1)
BDBM27580
PNG
(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(COc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C27H22ClNO3/c1-2-27(20-14-12-19(13-15-20)18-31-22-8-5-7-21(28)17-22)26(30)24-10-6-16-29(24)23-9-3-4-11-25(23)32-27/h3-17H,2,18H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
300 -9.25n/an/an/an/an/a7.537



Universita di Siena



Assay Description
The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...


J Med Chem 52: 1224-8 (2009)


Article DOI: 10.1021/jm801395v
BindingDB Entry DOI: 10.7270/Q237772D
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082059
PNG
(5-Ethyl-5-(3-fluoro-phenyl)-6-oxa-10b-aza-benzo[e]...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(F)c1
Show InChI InChI=1S/C20H16FNO2/c1-2-20(14-7-5-8-15(21)13-14)19(23)17-10-6-12-22(17)16-9-3-4-11-18(16)24-20/h3-13H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
400n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution V106A


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
750n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution L100I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.10E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution K103N


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082059
PNG
(5-Ethyl-5-(3-fluoro-phenyl)-6-oxa-10b-aza-benzo[e]...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(F)c1
Show InChI InChI=1S/C20H16FNO2/c1-2-20(14-7-5-8-15(21)13-14)19(23)17-10-6-12-22(17)16-9-3-4-11-18(16)24-20/h3-13H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.50E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y188L


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082058
PNG
(5-(3,5-Difluoro-phenyl)-5-ethyl-6-oxa-10b-aza-benz...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H15F2NO2/c1-2-20(13-10-14(21)12-15(22)11-13)19(24)17-7-5-9-23(17)16-6-3-4-8-18(16)25-20/h3-12H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.50E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against HIV-1 wild type reverse transcriptase (RT)


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082058
PNG
(5-(3,5-Difluoro-phenyl)-5-ethyl-6-oxa-10b-aza-benz...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H15F2NO2/c1-2-20(13-10-14(21)12-15(22)11-13)19(24)17-7-5-9-23(17)16-6-3-4-8-18(16)25-20/h3-12H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.70E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution L100I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.90E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y188L


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082058
PNG
(5-(3,5-Difluoro-phenyl)-5-ethyl-6-oxa-10b-aza-benz...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H15F2NO2/c1-2-20(13-10-14(21)12-15(22)11-13)19(24)17-7-5-9-23(17)16-6-3-4-8-18(16)25-20/h3-12H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.70E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution K103N


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082058
PNG
(5-(3,5-Difluoro-phenyl)-5-ethyl-6-oxa-10b-aza-benz...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H15F2NO2/c1-2-20(13-10-14(21)12-15(22)11-13)19(24)17-7-5-9-23(17)16-6-3-4-8-18(16)25-20/h3-12H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.00E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution V106A


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.90E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution V106A


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082059
PNG
(5-Ethyl-5-(3-fluoro-phenyl)-6-oxa-10b-aza-benzo[e]...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(F)c1
Show InChI InChI=1S/C20H16FNO2/c1-2-20(14-7-5-8-15(21)13-14)19(23)17-10-6-12-22(17)16-9-3-4-11-18(16)24-20/h3-13H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.00E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y181I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.00E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y181I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082058
PNG
(5-(3,5-Difluoro-phenyl)-5-ethyl-6-oxa-10b-aza-benz...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H15F2NO2/c1-2-20(13-10-14(21)12-15(22)11-13)19(24)17-7-5-9-23(17)16-6-3-4-8-18(16)25-20/h3-12H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.80E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y181I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.70E+3n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution K103N


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y188L


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y181I


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (Y181I)


(Human immunodeficiency virus type 1)
BDBM27580
PNG
(8-[4-(3-chlorophenoxymethyl)phenyl]-8-ethyl-9-oxa-...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc(COc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C27H22ClNO3/c1-2-27(20-14-12-19(13-15-20)18-31-22-8-5-7-21(28)17-22)26(30)24-10-6-16-29(24)23-9-3-4-11-25(23)32-27/h3-17H,2,18H2,1H3
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
<1.00E+4<-7.09n/an/an/an/an/a7.537



Universita di Siena



Assay Description
The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...


J Med Chem 52: 1224-8 (2009)


Article DOI: 10.1021/jm801395v
BindingDB Entry DOI: 10.7270/Q237772D
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50082058
PNG
(5-(3,5-Difluoro-phenyl)-5-ethyl-6-oxa-10b-aza-benz...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cc(F)cc(F)c1
Show InChI InChI=1S/C20H15F2NO2/c1-2-20(13-10-14(21)12-15(22)11-13)19(24)17-7-5-9-23(17)16-6-3-4-8-18(16)25-20/h3-12H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against HIV-1 mutant Reverse transcriptase containing the single amino acid substitution Y188L


J Med Chem 42: 4462-70 (1999)


Article DOI: 10.1021/jm990150o
BindingDB Entry DOI: 10.7270/Q20R9NMJ
More data for this
Ligand-Target Pair
Adenosine kinase


(Homo sapiens (Human))
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.50E+4n/an/an/an/an/an/a



Universita` di Siena

Curated by ChEMBL


Assay Description
Inhibition of human adenosine kinase


J Med Chem 54: 1401-20 (2011)


Article DOI: 10.1021/jm101438u
BindingDB Entry DOI: 10.7270/Q2XD120B
More data for this
Ligand-Target Pair
Adenosine kinase


(Homo sapiens (Human))
BDBM50052061
PNG
(5-Phenyl-6-oxa-10b-aza-benzo[e]azulen-4-one | CHEM...)
Show SMILES O=C1C(Oc2ccccc2-n2cccc12)c1ccccc1
Show InChI InChI=1S/C18H13NO2/c20-17-15-10-6-12-19(15)14-9-4-5-11-16(14)21-18(17)13-7-2-1-3-8-13/h1-12,18H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Universita` di Siena

Curated by ChEMBL


Assay Description
Inhibition of human adenosine kinase


J Med Chem 54: 1401-20 (2011)


Article DOI: 10.1021/jm101438u
BindingDB Entry DOI: 10.7270/Q2XD120B
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052046
PNG
(5-Ethyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C20H17NO2/c1-2-20(15-9-4-3-5-10-15)19(22)17-12-8-14-21(17)16-11-6-7-13-18(16)23-20/h3-14H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052049
PNG
(5-Ethyl-5-phenyl-6-oxa-12b-aza-naphtho[2,3-e]azule...)
Show SMILES CCC1(Oc2cc3ccccc3cc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C24H19NO2/c1-2-24(19-11-4-3-5-12-19)23(26)20-13-8-14-25(20)21-15-17-9-6-7-10-18(17)16-22(21)27-24/h3-16H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052048
PNG
(5-Allyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-on...)
Show SMILES C=CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C21H17NO2/c1-2-14-21(16-9-4-3-5-10-16)20(23)18-12-8-15-22(18)17-11-6-7-13-19(17)24-21/h2-13,15H,1,14H2
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052057
PNG
(5-Phenyl-5-propyl-6-oxa-10b-aza-benzo[e]azulen-4-o...)
Show SMILES CCCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C21H19NO2/c1-2-14-21(16-9-4-3-5-10-16)20(23)18-12-8-15-22(18)17-11-6-7-13-19(17)24-21/h3-13,15H,2,14H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052060
PNG
(5-Phenyl-6-oxa-12b-aza-naphtho[2,3-e]azulen-4-one ...)
Show SMILES O=C1C(Oc2cc3ccccc3cc2-n2cccc12)c1ccccc1
Show InChI InChI=1S/C22H15NO2/c24-21-18-11-6-12-23(18)19-13-16-9-4-5-10-17(16)14-20(19)25-22(21)15-7-2-1-3-8-15/h1-14,22H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052045
PNG
(5-(3-Methyl-but-2-enyl)-5-phenyl-6-oxa-10b-aza-ben...)
Show SMILES CC(C)=CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C23H21NO2/c1-17(2)14-15-23(18-9-4-3-5-10-18)22(25)20-12-8-16-24(20)19-11-6-7-13-21(19)26-23/h3-14,16H,15H2,1-2H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Adenosine kinase


(Homo sapiens (Human))
BDBM50082057
PNG
((+/-)-5-ethyl-5-m-tolyl-6-oxa-10b-aza-benzo[e]azul...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1cccc(C)c1
Show InChI InChI=1S/C21H19NO2/c1-3-21(16-9-6-8-15(2)14-16)20(23)18-11-7-13-22(18)17-10-4-5-12-19(17)24-21/h4-14H,3H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



Universita` di Siena

Curated by ChEMBL


Assay Description
Inhibition of human adenosine kinase


J Med Chem 54: 1401-20 (2011)


Article DOI: 10.1021/jm101438u
BindingDB Entry DOI: 10.7270/Q2XD120B
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052052
PNG
(5-Methyl-5-phenyl-6-oxa-10b-aza-benzo[e]azulen-4-o...)
Show SMILES CC1(Oc2ccccc2-n2cccc2C1=O)c1ccccc1
Show InChI InChI=1S/C19H15NO2/c1-19(14-8-3-2-4-9-14)18(21)16-11-7-13-20(16)15-10-5-6-12-17(15)22-19/h2-13H,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052051
PNG
(5-Ethyl-5-naphthalen-2-yl-6-oxa-10b-aza-benzo[e]az...)
Show SMILES CCC1(Oc2ccccc2-n2cccc2C1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C24H19NO2/c1-2-24(19-14-13-17-8-3-4-9-18(17)16-19)23(26)21-11-7-15-25(21)20-10-5-6-12-22(20)27-24/h3-16H,2H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052061
PNG
(5-Phenyl-6-oxa-10b-aza-benzo[e]azulen-4-one | CHEM...)
Show SMILES O=C1C(Oc2ccccc2-n2cccc12)c1ccccc1
Show InChI InChI=1S/C18H13NO2/c20-17-15-10-6-12-19(15)14-9-4-5-11-16(14)21-18(17)13-7-2-1-3-8-13/h1-12,18H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052065
PNG
(5-Naphthalen-2-yl-6-oxa-10b-aza-benzo[e]azulen-4-o...)
Show SMILES O=C1C(Oc2ccccc2-n2cccc12)c1ccc2ccccc2c1
Show InChI InChI=1S/C22H15NO2/c24-21-19-9-5-13-23(19)18-8-3-4-10-20(18)25-22(21)17-12-11-15-6-1-2-7-16(15)14-17/h1-14,22H
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50052055
PNG
(5-Cyclopropylmethyl-5-phenyl-6-oxa-10b-aza-benzo[e...)
Show SMILES O=C1c2cccn2-c2ccccc2OC1(CC1CC1)c1ccccc1
Show InChI InChI=1S/C22H19NO2/c24-21-19-10-6-14-23(19)18-9-4-5-11-20(18)25-22(21,15-16-12-13-16)17-7-2-1-3-8-17/h1-11,14,16H,12-13,15H2
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Universitá di Siena

Curated by ChEMBL


Assay Description
Compound was tested for Inhibition of HIV-1 RT activity.


J Med Chem 39: 2672-80 (1996)


Article DOI: 10.1021/jm950702c
BindingDB Entry DOI: 10.7270/Q21R6PM4
More data for this
Ligand-Target Pair