Compounds in cluster

144 similar compounds to monomer 29643

Wt: 267.3 BDBM29644 Purchase	Wt: 355.4 BDBM35523 Purchase	Wt: 311.3 BDBM52987	Wt: 283.3 BDBM52988	Wt: 356.4 BDBM70843 Purchase
Wt: 313.3 BDBM82569	Wt: 279.3 BDBM84632	Wt: 279.3 BDBM84636	Wt: 281.3 BDBM86893	Wt: 297.3 BDBM86894
Wt: 309.4 BDBM86895	Wt: 325.4 BDBM86897	Wt: 295.3 BDBM86898	Wt: 251.3 BDBM86892	Wt: 267.3 BDBM86896

Displayed 1 to 15 (of 144 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 103 hits for monomerid = 29644,35523,52987,52988,70843,82569,84632,84636,86893,86894,86895,86897,86898,86892,86896
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM52987 ((6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from rat dopamine D2 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM52987 ((6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Binding affinity at rat striatal Dopamine receptor D2 using [3H]- piperone radioligand				J Med Chem 33: 1800-5 (1990) Article DOI: 10.1021/jm00168a040 BindingDB Entry DOI: 10.7270/Q2K35SMD
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM82569 (CAS_18426-20-5 \| NSC_131212 \| R(-)NPA) Show SMILES CCCN1CCc2cc(F)cc-3c2C1Cc1ccc(O)c(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience Research Centre Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 417-26 (1994) Article DOI: 10.1016/j.bioorg.2015.06.003 BindingDB Entry DOI: 10.7270/Q2C827SR
Neuroscience Research Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM82569 (CAS_18426-20-5 \| NSC_131212 \| R(-)NPA) Show SMILES CCCN1CCc2cc(F)cc-3c2C1Cc1ccc(O)c(O)c-31 Show InChI	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience Research Centre Curated by PDSP K_i Database									J Pharmacol Exp Ther 268: 417-26 (1994) Article DOI: 10.1016/j.bioorg.2015.06.003 BindingDB Entry DOI: 10.7270/Q2C827SR
Neuroscience Research Centre Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit Dopamine receptor D2 in rat striatum using [3H]spiperone				J Med Chem 34: 24-8 (1991) Article DOI: 10.1021/jm00105a005 BindingDB Entry DOI: 10.7270/Q24Q7VKQ
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (BOVINE)	BDBM52987 ((6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand				J Med Chem 33: 1800-5 (1990) Article DOI: 10.1021/jm00168a040 BindingDB Entry DOI: 10.7270/Q2K35SMD
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from human cloned dopamine D3 receptor high binding site expressed in mouse CCL1-3 cells by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 from rat brain corpus striatal preparations using [3H]-Spiperone				J Med Chem 31: 1392-6 (1988) Article DOI: 10.1021/jm00402a024 BindingDB Entry DOI: 10.7270/Q2WW7GP2
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Binding affinity against dopamine agonist sites from rat brain corpus striatal preparations using [3H]ADTN				J Med Chem 31: 1392-6 (1988) Article DOI: 10.1021/jm00402a024 BindingDB Entry DOI: 10.7270/Q2WW7GP2
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit Striatal Dopamine receptor in rat brain through radioreceptor assay carried out with agonist ligand...				J Med Chem 34: 24-8 (1991) Article DOI: 10.1021/jm00105a005 BindingDB Entry DOI: 10.7270/Q24Q7VKQ
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human Dopamine receptor D2A				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM84632 (CAS_132-66-1 \| NPA-11-OH-R,(-)) Show SMILES CCCN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM86892 ((R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES CN1CCc2cccc-3c2C1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	26.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP K_i Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
McLean Hospital Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]nemonapride from dopamine D2 receptor in rat forebrain				Bioorg Med Chem Lett 19: 51-3 (2008) Article DOI: 10.1016/j.bmcl.2008.11.025 BindingDB Entry DOI: 10.7270/Q26W99XP
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]neomonapride from dopamine D2 receptor in rat corpus striatum				Bioorg Med Chem Lett 18: 3971-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.016 BindingDB Entry DOI: 10.7270/Q2S46RRC
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from rat dopamine D2 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (Rat))	BDBM29644 ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cells				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (Rat))	BDBM29644 ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cells				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM29644 ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...				Bioorg Med Chem Lett 11: 367-70 (2001) Article DOI: 10.1016/s0960-894x(00)00655-7 BindingDB Entry DOI: 10.7270/Q2N8792J
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 53: 1319-28 (2010) Article DOI: 10.1021/jm9015763 BindingDB Entry DOI: 10.7270/Q2T154KK
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8OH-DPAT from human dopamine D1 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM86893 (2-Methoxy-11-hydroxyaporphine \| CAS_24766199 \| NSC...) Show SMILES COc1cc2CCN(C)C3Cc4cccc(O)c4-c(c1)c23 Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP K_i Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
McLean Hospital Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM29644 ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Debrecen Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membrane				Bioorg Med Chem 16: 3773-9 (2008) Article DOI: 10.1016/j.bmc.2008.01.057 BindingDB Entry DOI: 10.7270/Q2959HB7
University of Debrecen Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM84632 (CAS_132-66-1 \| NPA-11-OH-R,(-)) Show SMILES CCCN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1319-28 (2010) Article DOI: 10.1021/jm9015763 BindingDB Entry DOI: 10.7270/Q2T154KK
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human 5HT2A receptor expressed in HEK293 cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM86898 ((R)-(-)-N-ethyl-2-methoxy-11-hydroxynoraporphine \|...) Show SMILES CCN1CCc2cc(OC)cc-3c2C1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP K_i Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
McLean Hospital Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM29644 ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Non-competitive inhibition against Candida albicans prolyl-tRNA synthetase (Ca. ProRS) with respect to proline				Bioorg Med Chem Lett 11: 367-70 (2001) Article DOI: 10.1016/s0960-894x(00)00655-7 BindingDB Entry DOI: 10.7270/Q2N8792J
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM29644 ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 variant with Y181C plus K103N mutatio...				Bioorg Med Chem Lett 11: 367-70 (2001) Article DOI: 10.1016/s0960-894x(00)00655-7 BindingDB Entry DOI: 10.7270/Q2N8792J
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	434	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 from rat brain corpus striatal preparations using [3H]-SCH-23,390				J Med Chem 31: 1392-6 (1988) Article DOI: 10.1021/jm00402a024 BindingDB Entry DOI: 10.7270/Q2WW7GP2
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	434	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit Dopamine receptor D1 in rat striatum using [3H]SCH-23390				J Med Chem 34: 24-8 (1991) Article DOI: 10.1021/jm00105a005 BindingDB Entry DOI: 10.7270/Q24Q7VKQ
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	699	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in rat forebrain				Bioorg Med Chem Lett 19: 51-3 (2008) Article DOI: 10.1016/j.bmcl.2008.11.025 BindingDB Entry DOI: 10.7270/Q26W99XP
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	699	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in rat corpus striatum				Bioorg Med Chem Lett 18: 3971-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.016 BindingDB Entry DOI: 10.7270/Q2S46RRC
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from rat dopamine D1 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	789	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Eur J Pharmacol 233: 173-4 (1993) Article DOI: 10.1016/0014-2999(93)90365-o BindingDB Entry DOI: 10.7270/Q25D8QBH
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM52987 ((6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	915	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Binding affinity at rat striatal Dopamine receptor D1 using [3H]- SCH-23390 radioligand				J Med Chem 33: 1800-5 (1990) Article DOI: 10.1021/jm00168a040 BindingDB Entry DOI: 10.7270/Q2K35SMD
Northeastern University Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM52987 ((6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from rat dopamine D1 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM86896 (APOMORPHINE \| CAS_314-19-2 \| NSC_2215) Show SMILES CN1CCc2cccc-3c2C1Cc1ccc(O)c(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP K_i Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
McLean Hospital Curated by PDSP K_i Database					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro displacement of [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1				J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM86895 (2-methoxy-11-hydroxy-N-propylnoraporphine \| CAS_24...) Show SMILES CCCN1CCc2cc(OC)cc-3c2C1Cc1cccc(O)c-31 Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP K_i Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
McLean Hospital Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]domperidone from human cloned dopamine D3 receptor expressed in mouse CCL1-3 cells by scintillation counting				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assay				ACS Med Chem Lett 2: 189-194 (2011) Article DOI: 10.1021/ml1001689 BindingDB Entry DOI: 10.7270/Q2Z89DF8
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
DOPAMINE (RAT)	BDBM86897 (2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	6.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McLean Hospital Curated by PDSP K_i Database									J Med Chem 51: 983-7 (2008) Article DOI: 10.1021/jm701045j BindingDB Entry DOI: 10.7270/Q2V69H59
McLean Hospital Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from rat 5HT1A receptor expressed in CHO cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM84636 (CHEMBL27559 \| NPA-11-OH-R,(+)) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human dopamine D2 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

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