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1 similar compounds to monomer 29666

Compile data set for download or QSAR
Wt: 462.5
BDBM29665

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29665   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens (Human))
BDBM29665
PNG
((9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl...)
Show SMILES Cc1cc(C=NNC(=O)Cn2c3ccccc3c(=O)c3ccccc23)c(C)n1-c1ccc(C)cc1
Show InChI InChI=1S/C29H26N4O2/c1-19-12-14-23(15-13-19)33-20(2)16-22(21(33)3)17-30-31-28(34)18-32-26-10-6-4-8-24(26)29(35)25-9-5-7-11-27(25)32/h4-17H,18H2,1-3H3,(H,31,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PCBioAssay
n/an/a 1.30E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


Article DOI: 10.1038/42506
BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens (Human))
BDBM29665
PNG
((9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl...)
Show SMILES Cc1cc(C=NNC(=O)Cn2c3ccccc3c(=O)c3ccccc23)c(C)n1-c1ccc(C)cc1
Show InChI InChI=1S/C29H26N4O2/c1-19-12-14-23(15-13-19)33-20(2)16-22(21(33)3)17-30-31-28(34)18-32-26-10-6-4-8-24(26)29(35)25-9-5-7-11-27(25)32/h4-17H,18H2,1-3H3,(H,31,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 1.30E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair