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5 similar compounds to monomer 50050498

Wt: 241.2
BDBM30812
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Wt: 284.3
BDBM73457
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Wt: 360.4
BDBM50050499
Wt: 346.3
BDBM50050435
Wt: 390.4
BDBM50050502

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 30812,73457,50050499,50050435,50050502   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM30812
PNG
(3-methoxy-N-(4-methylphenyl)benzamide | 3-methoxy-...)
Show SMILES COc1cccc(c1)C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C15H15NO2/c1-11-6-8-13(9-7-11)16-15(17)12-4-3-5-14(10-12)18-2/h3-10H,1-2H3,(H,16,17)
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PCBioAssay
n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)

More data for this
Ligand-Target Pair
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM30812
PNG
(3-methoxy-N-(4-methylphenyl)benzamide | 3-methoxy-...)
Show SMILES COc1cccc(c1)C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C15H15NO2/c1-11-6-8-13(9-7-11)16-15(17)12-4-3-5-14(10-12)18-2/h3-10H,1-2H3,(H,16,17)
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B.MOAD
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PCBioAssay
n/an/an/an/a 8.76E+3n/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
LANA


(Human herpesvirus 8)
BDBM73457
PNG
(MLS000536600 | N-(4-acetamidophenyl)-3-methoxy-ben...)
Show SMILES COc1cccc(c1)C(=O)Nc1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C16H16N2O3/c1-11(19)17-13-6-8-14(9-7-13)18-16(20)12-4-3-5-15(10-12)21-2/h3-10H,1-2H3,(H,17,19)(H,18,20)
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PCBioAssay
n/an/an/an/a>7.50E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...


PubChem Bioassay (2010)

More data for this
Ligand-Target Pair
Potassium channel protein TASK-1


(Homo sapiens (Human))
BDBM50050435
PNG
(CHEMBL3183938)
Show SMILES COc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C21H18N2O3/c1-26-19-12-5-9-16(13-19)21(25)23-18-11-6-10-17(14-18)22-20(24)15-7-3-2-4-8-15/h2-14H,1H3,(H,22,24)(H,23,25)
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Article
PubMed
n/an/a 330n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050502
PNG
(CHEMBL3317851)
Show SMILES COc1ccc(OC)c(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C23H22N2O4/c1-15-6-4-7-16(12-15)22(26)24-17-8-5-9-18(13-17)25-23(27)20-14-19(28-2)10-11-21(20)29-3/h4-14H,1-3H3,(H,24,26)(H,25,27)
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Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel protein TASK-1


(Homo sapiens (Human))
BDBM50050502
PNG
(CHEMBL3317851)
Show SMILES COc1ccc(OC)c(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C23H22N2O4/c1-15-6-4-7-16(12-15)22(26)24-17-8-5-9-18(13-17)25-23(27)20-14-19(28-2)10-11-21(20)29-3/h4-14H,1-3H3,(H,24,26)(H,25,27)
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Article
PubMed
n/an/a 150n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050435
PNG
(CHEMBL3183938)
Show SMILES COc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C21H18N2O3/c1-26-19-12-5-9-16(13-19)21(25)23-18-11-6-10-17(14-18)22-20(24)15-7-3-2-4-8-15/h2-14H,1H3,(H,22,24)(H,23,25)
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Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050499
PNG
(CHEMBL3188671)
Show SMILES COc1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-5-3-6-17(13-15)22(26)24-19-8-4-7-18(14-19)23-21(25)16-9-11-20(27-2)12-10-16/h3-14H,1-2H3,(H,23,25)(H,24,26)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel protein TASK-1


(Homo sapiens (Human))
BDBM50050499
PNG
(CHEMBL3188671)
Show SMILES COc1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-5-3-6-17(13-15)22(26)24-19-8-4-7-18(14-19)23-21(25)16-9-11-20(27-2)12-10-16/h3-14H,1-2H3,(H,23,25)(H,24,26)
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Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair