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5 similar compounds to monomer 81498

Compile data set for download or QSAR
Wt: 198.2
BDBM31023
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Wt: 214.2
BDBM50015714
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Wt: 318.4
BDBM50154709
Wt: 242.3
BDBM50171236
Wt: 242.3
BDBM50209169
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 31023,50015714,50154709,50171236,50209169   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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6n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.


Bioorg Med Chem Lett 13: 405-8 (2003)


Article DOI: 10.1016/s0960-894x(02)00996-4
BindingDB Entry DOI: 10.7270/Q2Z89BSX
More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM50209169
PNG
(5-Methoxy-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]cc(C3=CCN(C)CC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-17-7-5-11(6-8-17)14-10-16-15-4-3-12(18-2)9-13(14)15/h3-5,9-10,16H,6-8H2,1-2H3
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21n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand.


J Med Chem 36: 4006-14 (1993)

More data for this
Ligand-Target Pair
Serotonin 1 (5-HT1) receptor


(Rattus norvegicus (rat))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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189n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand.


J Med Chem 36: 4006-14 (1993)

More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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200n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned dopamine receptor D2 (long) stably expressed in CHO cells by [3H]-Spiperone displacement.


Bioorg Med Chem Lett 13: 405-8 (2003)


Article DOI: 10.1016/s0960-894x(02)00996-4
BindingDB Entry DOI: 10.7270/Q2Z89BSX
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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204n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]-ketanserin as radioligand.


J Med Chem 36: 4006-14 (1993)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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296n/an/an/an/an/an/an/an/a



Monash University (Parkville Campus)

Curated by ChEMBL


Assay Description
Displacement of [3H]-mesulergine from 5HT2C receptor expressed in CHO cell membranes after 90 mins by scintillation counting


Bioorg Med Chem Lett 22: 2560-4 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.122
BindingDB Entry DOI: 10.7270/Q2JD4XSQ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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632n/an/an/an/an/an/an/an/a



Monash University (Parkville Campus)

Curated by ChEMBL


Assay Description
Displacement of [3H]-mesulergine from 5HT2C receptor expressed in CHO cell membranes using 11 concentration of ligand after 90 mins by scintillation ...


Bioorg Med Chem Lett 22: 2560-4 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.122
BindingDB Entry DOI: 10.7270/Q2JD4XSQ
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50209169
PNG
(5-Methoxy-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]cc(C3=CCN(C)CC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-17-7-5-11(6-8-17)14-10-16-15-4-3-12(18-2)9-13(14)15/h3-5,9-10,16H,6-8H2,1-2H3
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897n/an/an/an/an/an/an/an/a



University of Georgia

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]-ketanserin as radioligand.


J Med Chem 36: 4006-14 (1993)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50154709
PNG
(3-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-met...)
Show SMILES COc1ccc2[nH]cc(C3=CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C21H22N2O/c1-24-18-7-8-21-19(13-18)20(14-22-21)17-9-11-23(12-10-17)15-16-5-3-2-4-6-16/h2-9,13-14,22H,10-12,15H2,1H3
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1.10E+3n/an/an/an/an/an/an/an/a



State University of Groningen

Curated by ChEMBL


Assay Description
Binding affinity towards rat 5-HT7 receptor expressed in HEK cells


J Med Chem 47: 5451-66 (2004)


Article DOI: 10.1021/jm049743b
BindingDB Entry DOI: 10.7270/Q2TB16C9
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a 80n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 6 receptor in human


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 3A


(Homo sapiens (Human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 3 receptor expressed in NG 108 cells


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a 430n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 1A receptor in rat


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 1D receptor in calf


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a 310n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 1B receptor in rat


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 2C receptor in human


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a>1.00E+3n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 2A receptor in human


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a 9.80E+3n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 7 receptor in human


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
HTR4


(GUINEA PIG)
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a 9.80E+3n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor in guinea pig


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (human))
BDBM50209169
PNG
(5-Methoxy-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]cc(C3=CCN(C)CC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-17-7-5-11(6-8-17)14-10-16-15-4-3-12(18-2)9-13(14)15/h3-5,9-10,16H,6-8H2,1-2H3
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n/an/a 730n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]citalopram from human SERT expressed in HEK293 cells


Bioorg Med Chem Lett 17: 3099-104 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.040
BindingDB Entry DOI: 10.7270/Q2QN66F8
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/an/an/a 163n/an/an/an/a



Monash University (Parkville Campus)

Curated by ChEMBL


Assay Description
Agonist activity at 5HT2C receptor expressed in CHO cells by fluorescence based calcium mobilization assay


Bioorg Med Chem Lett 22: 2560-4 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.122
BindingDB Entry DOI: 10.7270/Q2JD4XSQ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50171236
PNG
(5-Methoxy-2-methyl-3-(1,2,3,6-tetrahydro-pyridin-4...)
Show SMILES COc1ccc2[nH]c(C)c(C3=CCNCC3)c2c1
Show InChI InChI=1S/C15H18N2O/c1-10-15(11-5-7-16-8-6-11)13-9-12(18-2)3-4-14(13)17-10/h3-5,9,16-17H,6-8H2,1-2H3
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n/an/a 80n/an/an/an/an/an/a



Carlsson Research AB

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD binding to cloned human 5-hydroxytryptamine 6 receptor expressed in HEK cells


Bioorg Med Chem Lett 15: 4230-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.067
BindingDB Entry DOI: 10.7270/Q2ZG6RST
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/a 3.70n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT as the radioligand.


J Med Chem 33: 2087-93 (1990)


Article DOI: 10.1021/jm00170a007
BindingDB Entry DOI: 10.7270/Q2GQ6WR3
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/a 140n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor


J Med Chem 33: 2087-93 (1990)


Article DOI: 10.1021/jm00170a007
BindingDB Entry DOI: 10.7270/Q2GQ6WR3
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50015714
PNG
(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)
Show SMILES Oc1ccc2[nH]cc(C3=CCNCC3)c2c1
Show InChI InChI=1S/C13H14N2O/c16-10-1-2-13-11(7-10)12(8-15-13)9-3-5-14-6-4-9/h1-3,7-8,14-16H,4-6H2
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n/an/a 30n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from rat cortex 5-hydroxytryptamine 1A receptor


J Med Chem 33: 2087-93 (1990)


Article DOI: 10.1021/jm00170a007
BindingDB Entry DOI: 10.7270/Q2GQ6WR3
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50015714
PNG
(3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indol-5-ol ...)
Show SMILES Oc1ccc2[nH]cc(C3=CCNCC3)c2c1
Show InChI InChI=1S/C13H14N2O/c16-10-1-2-13-11(7-10)12(8-15-13)9-3-5-14-6-4-9/h1-3,7-8,14-16H,4-6H2
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n/an/a 1.20n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 1B receptor of rat cortex using [3H]-5-HT


J Med Chem 33: 2087-93 (1990)


Article DOI: 10.1021/jm00170a007
BindingDB Entry DOI: 10.7270/Q2GQ6WR3
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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PCBioAssay
n/an/an/an/a>4.00E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
External Assay ID: S1P3_EC50_CS_5HT1e_Agonist Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2PN941W
More data for this
Ligand-Target Pair
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/a 2.53E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769ZM
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase (PKA)


(Homo sapiens (human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/a>5.96E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q24X565S
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/an/an/a 5.00E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2WW7G03
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Homo sapiens)
BDBM31023
PNG
(3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | CHE...)
Show SMILES C1CC(=CCN1)c1c[nH]c2ccccc12
Show InChI InChI=1S/C13H14N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-5,9,14-15H,6-8H2
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n/an/an/an/a 15.7n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Q52MZM
More data for this
Ligand-Target Pair