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3 similar compounds to monomer 31917

Compile data set for download or QSAR
Wt: 257.2
BDBM31918
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Wt: 399.0
BDBM31919
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Wt: 443.0
BDBM31921

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31918,31919,31921   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31918
PNG
(carbohydrazide derivative, 3a)
Show SMILES Oc1ccc(\C=N\NC(=O)c2cccnc2)c(O)c1
Show InChI InChI=1S/C13H11N3O3/c17-11-4-3-9(12(18)6-11)8-15-16-13(19)10-2-1-5-14-7-10/h1-8,17-18H,(H,16,19)/b15-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31921
PNG
(carbohydrazide derivative, 3d)
Show SMILES COc1c(Br)cc(\C=N\NC(=O)c2cccnc2)c(OC)c1Br
Show InChI InChI=1S/C15H13Br2N3O3/c1-22-13-10(6-11(16)14(23-2)12(13)17)8-19-20-15(21)9-4-3-5-18-7-9/h3-8H,1-2H3,(H,20,21)/b19-8+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31919
PNG
(carbohydrazide derivative, 3b)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2cccnc2)cc1Br
Show InChI InChI=1S/C13H9Br2N3O2/c14-10-4-8(5-11(15)12(10)19)6-17-18-13(20)9-2-1-3-16-7-9/h1-7,19H,(H,18,20)/b17-6+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair