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17 similar compounds to monomer 31965

Compile data set for download or QSAR
Wt: 492.9
BDBM31927
Wt: 492.9
BDBM31928
Purchase
Wt: 430.0
BDBM31958
Purchase
Wt: 506.1
BDBM31959
Wt: 490.1
BDBM31962
Wt: 480.1
BDBM31964
Wt: 480.1
BDBM31966
Wt: 543.0
BDBM31967
Wt: 414.0
BDBM31922
Purchase
Wt: 464.1
BDBM31930
Wt: 444.0
BDBM31931
Purchase
Wt: 385.2
BDBM50420542
Purchase
Wt: 540.2
BDBM50428988
Wt: 494.1
BDBM50428990
Wt: 489.1
BDBM50428991
Displayed 1 to 15 (of 17 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 31927,31928,31958,31959,31962,31964,31966,31967,31922,31930,31931,50420542,50428988,50428990,50428991   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31922
PNG
(carbohydrazide derivative, 3e)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccccc2)c(O)c1Br
Show InChI InChI=1S/C14H10Br2N2O3/c15-10-6-9(12(19)11(16)13(10)20)7-17-18-14(21)8-4-2-1-3-5-8/h1-7,19-20H,(H,18,21)/b17-7+
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n/an/an/an/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
NAD-dependent deacetylase sirtuin 2


(Homo sapiens (Human))
BDBM50428988
PNG
(CHEMBL2333666)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3cc(ccc3c2)-c2ccccc2)c(O)c1Br
Show InChI InChI=1S/C24H16Br2N2O3/c25-20-12-19(22(29)21(26)23(20)30)13-27-28-24(31)18-9-8-16-10-15(6-7-17(16)11-18)14-4-2-1-3-5-14/h1-13,29-30H,(H,28,31)/b27-13+
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n/an/an/an/a 1.16E+4n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of at N-terminal GST-tagged SIRT2 (34 to 356 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31928
PNG
(carbohydrazide derivative, 3k)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2cccc(Br)c2)c(O)c1Br
Show InChI InChI=1S/C14H9Br3N2O3/c15-9-3-1-2-7(4-9)14(22)19-18-6-8-5-10(16)13(21)11(17)12(8)20/h1-6,20-21H,(H,19,22)/b18-6+
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n/an/a 1.98E+3n/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31930
PNG
(carbohydrazide derivative, 3m)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3ccccc3c2)c(O)c1Br
Show InChI InChI=1S/C18H12Br2N2O3/c19-14-8-13(16(23)15(20)17(14)24)9-21-22-18(25)12-6-5-10-3-1-2-4-11(10)7-12/h1-9,23-24H,(H,22,25)/b21-9+
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n/an/a 1.42E+3n/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31931
PNG
(carbohydrazide derivative, 3n)
Show SMILES COc1ccc(cc1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O
Show InChI InChI=1S/C15H12Br2N2O4/c1-23-10-4-2-8(3-5-10)15(22)19-18-7-9-6-11(16)14(21)12(17)13(9)20/h2-7,20-21H,1H3,(H,19,22)/b18-7+
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n/an/a 9.92E+3n/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31958
PNG
(carbohydrazide derivative, 5a)
Show SMILES Oc1ccc(cc1)C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O
Show InChI InChI=1S/C14H10Br2N2O4/c15-10-5-8(12(20)11(16)13(10)21)6-17-18-14(22)7-1-3-9(19)4-2-7/h1-6,19-21H,(H,18,22)
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n/an/an/an/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31959
PNG
(carbohydrazide derivative, 5b)
Show SMILES Oc1ccc(cc1)-c1ccc(cc1)C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O
Show InChI InChI=1S/C20H14Br2N2O4/c21-16-9-14(18(26)17(22)19(16)27)10-23-24-20(28)13-3-1-11(2-4-13)12-5-7-15(25)8-6-12/h1-10,25-27H,(H,24,28)
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n/an/a 4.27E+4n/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31962
PNG
(carbohydrazide derivative, 5e)
Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1Br
Show InChI InChI=1S/C20H14Br2N2O3/c21-16-10-15(18(25)17(22)19(16)26)11-23-24-20(27)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-11,25-26H,(H,24,27)
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n/an/an/an/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31964
PNG
(carbohydrazide derivative, 5g)
Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc3ccccc3c2O)c(O)c1Br
Show InChI InChI=1S/C18H12Br2N2O4/c19-13-7-10(15(23)14(20)17(13)25)8-21-22-18(26)12-6-5-9-3-1-2-4-11(9)16(12)24/h1-8,23-25H,(H,22,26)
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n/an/a 1.97E+3n/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31966
PNG
(carbohydrazide derivative, 5i)
Show SMILES Oc1ccc2cc(ccc2c1)C(=O)NN=Cc1cc(Br)c(O)c(Br)c1O
Show InChI InChI=1S/C18H12Br2N2O4/c19-14-7-12(16(24)15(20)17(14)25)8-21-22-18(26)11-2-1-10-6-13(23)4-3-9(10)5-11/h1-8,23-25H,(H,22,26)
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n/an/a 8.77E+3n/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31967
PNG
(carbohydrazide derivative, 5j)
Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc3cc(Br)ccc3c2)c(O)c1Br
Show InChI InChI=1S/C18H11Br3N2O3/c19-13-4-3-9-5-11(2-1-10(9)6-13)18(26)23-22-8-12-7-14(20)17(25)15(21)16(12)24/h1-8,24-25H,(H,23,26)
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n/an/a 3.55E+3n/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50420542
PNG
(CHEMBL2086965)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)c1cc2ccccc2cc1O
Show InChI InChI=1S/C18H13BrN2O3/c19-14-5-6-16(22)13(7-14)10-20-21-18(24)15-8-11-3-1-2-4-12(11)9-17(15)23/h1-10,22-23H,(H,21,24)/b20-10+
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n/an/a>1.00E+5n/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of fluorescent labelled SRC1-4 from dexamethasone-GR complex after 2 to 4 hrs by TR-FRET assay


J Med Chem 55: 1635-44 (2012)


Article DOI: 10.1021/jm201438f
BindingDB Entry DOI: 10.7270/Q27W6DG8
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM50420542
PNG
(CHEMBL2086965)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)c1cc2ccccc2cc1O
Show InChI InChI=1S/C18H13BrN2O3/c19-14-5-6-16(22)13(7-14)10-20-21-18(24)15-8-11-3-1-2-4-12(11)9-17(15)23/h1-10,22-23H,(H,21,24)/b20-10+
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n/an/a>1.00E+5n/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of fluorescent labelled PGC-1alpha from estradiol-ERalpha complex after 2 to 4 hrs by TR-FRET assay


J Med Chem 55: 1635-44 (2012)


Article DOI: 10.1021/jm201438f
BindingDB Entry DOI: 10.7270/Q27W6DG8
More data for this
Ligand-Target Pair
Estradiol receptor beta (ERβ)


(Homo sapiens (Human))
BDBM50420542
PNG
(CHEMBL2086965)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)c1cc2ccccc2cc1O
Show InChI InChI=1S/C18H13BrN2O3/c19-14-5-6-16(22)13(7-14)10-20-21-18(24)15-8-11-3-1-2-4-12(11)9-17(15)23/h1-10,22-23H,(H,21,24)/b20-10+
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n/an/a>1.00E+5n/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of fluorescent labelled PGC-1alpha from estradiol-ERbeta complex after 2 to 4 hrs by TR-FRET assay


J Med Chem 55: 1635-44 (2012)


Article DOI: 10.1021/jm201438f
BindingDB Entry DOI: 10.7270/Q27W6DG8
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50420542
PNG
(CHEMBL2086965)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)c1cc2ccccc2cc1O
Show InChI InChI=1S/C18H13BrN2O3/c19-14-5-6-16(22)13(7-14)10-20-21-18(24)15-8-11-3-1-2-4-12(11)9-17(15)23/h1-10,22-23H,(H,21,24)/b20-10+
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n/an/a 2.25E+4n/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Antagonist activity at PR assessed as inhibition of progesterone-induced fluorescent labelled SRC1-4 recruitment after 2 to 4 hrs by TR-FRET assay


J Med Chem 55: 1635-44 (2012)


Article DOI: 10.1021/jm201438f
BindingDB Entry DOI: 10.7270/Q27W6DG8
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50420542
PNG
(CHEMBL2086965)
Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)c1cc2ccccc2cc1O
Show InChI InChI=1S/C18H13BrN2O3/c19-14-5-6-16(22)13(7-14)10-20-21-18(24)15-8-11-3-1-2-4-12(11)9-17(15)23/h1-10,22-23H,(H,21,24)/b20-10+
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n/an/a 1.33E+4n/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Antagonist activity at wild type AR LBD assessed as inhibition of DHT-induced fluorescent labeled D11-FxxLF recruitment after 2 to 4 hrs by TR-FRET a...


J Med Chem 55: 1635-44 (2012)


Article DOI: 10.1021/jm201438f
BindingDB Entry DOI: 10.7270/Q27W6DG8
More data for this
Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1


(Homo sapiens (Human))
BDBM50428988
PNG
(CHEMBL2333666)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3cc(ccc3c2)-c2ccccc2)c(O)c1Br
Show InChI InChI=1S/C24H16Br2N2O3/c25-20-12-19(22(29)21(26)23(20)30)13-27-28-24(31)18-9-8-16-10-15(6-7-17(16)11-18)14-4-2-1-3-5-14/h1-13,29-30H,(H,28,31)/b27-13+
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n/an/an/an/a 1.80E+3n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1


(Homo sapiens (Human))
BDBM50428990
PNG
(CHEMBL2333664)
Show SMILES COc1ccc2cc(ccc2c1)C(=O)N\N=C\c1cc(Br)c(O)c(Br)c1O
Show InChI InChI=1S/C19H14Br2N2O4/c1-27-14-5-4-10-6-12(3-2-11(10)7-14)19(26)23-22-9-13-8-15(20)18(25)16(21)17(13)24/h2-9,24-25H,1H3,(H,23,26)/b22-9+
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n/an/an/an/a 900n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1


(Homo sapiens (Human))
BDBM50428991
PNG
(CHEMBL2333663)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3cc(ccc3c2)C#N)c(O)c1Br
Show InChI InChI=1S/C19H11Br2N3O3/c20-15-7-14(17(25)16(21)18(15)26)9-23-24-19(27)13-4-3-11-5-10(8-22)1-2-12(11)6-13/h1-7,9,25-26H,(H,24,27)/b23-9+
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n/an/an/an/a 4.40E+3n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1


(Homo sapiens (Human))
BDBM31967
PNG
(carbohydrazide derivative, 5j)
Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc3cc(Br)ccc3c2)c(O)c1Br
Show InChI InChI=1S/C18H11Br3N2O3/c19-13-4-3-9-5-11(2-1-10(9)6-13)18(26)23-22-8-12-7-14(20)17(25)15(21)16(12)24/h1-8,24-25H,(H,23,26)
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n/an/an/an/a 2.70E+3n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1


(Homo sapiens (Human))
BDBM31930
PNG
(carbohydrazide derivative, 3m)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3ccccc3c2)c(O)c1Br
Show InChI InChI=1S/C18H12Br2N2O3/c19-14-8-13(16(23)15(20)17(14)24)9-21-22-18(25)12-6-5-10-3-1-2-4-11(10)7-12/h1-9,23-24H,(H,22,25)/b21-9+
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n/an/an/an/a 1.60E+3n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
NAD-Dependent Deacetylase Sirtuin-1


(Homo sapiens (Human))
BDBM31962
PNG
(carbohydrazide derivative, 5e)
Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(cc2)-c2ccccc2)c(O)c1Br
Show InChI InChI=1S/C20H14Br2N2O3/c21-16-10-15(18(25)17(22)19(16)26)11-23-24-20(27)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-11,25-26H,(H,24,27)
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n/an/an/an/a 1.70E+3n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT1 (156 to 664 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3 (SIRT3)


(Homo sapiens (Human))
BDBM50428988
PNG
(CHEMBL2333666)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc3cc(ccc3c2)-c2ccccc2)c(O)c1Br
Show InChI InChI=1S/C24H16Br2N2O3/c25-20-12-19(22(29)21(26)23(20)30)13-27-28-24(31)18-9-8-16-10-15(6-7-17(16)11-18)14-4-2-1-3-5-14/h1-13,29-30H,(H,28,31)/b27-13+
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n/an/an/an/a 2.86E+4n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Activation of N-terminal His6-tagged SIRT3 (118 to 399 amino acid residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using ac-RHKKac-...


J Med Chem 56: 761-80 (2013)


Article DOI: 10.1021/jm301032j
BindingDB Entry DOI: 10.7270/Q2XP768M
More data for this
Ligand-Target Pair
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31927
PNG
(carbohydrazide derivative, 3j)
Show SMILES Oc1c(Br)cc(\C=N\NC(=O)c2ccc(Br)cc2)c(O)c1Br
Show InChI InChI=1S/C14H9Br3N2O3/c15-9-3-1-7(2-4-9)14(22)19-18-6-8-5-10(16)13(21)11(17)12(8)20/h1-6,20-21H,(H,19,22)/b18-6+
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n/an/a 1.50E+3n/an/an/an/a8.025



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)