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23 similar compounds to monomer 50314418

Compile data set for download or QSAR
Wt: 299.3
BDBM32271
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Wt: 389.4
BDBM40169
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Wt: 295.3
BDBM42615
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Wt: 403.4
BDBM77203
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Wt: 375.4
BDBM83500
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Wt: 273.3
BDBM50302202
Wt: 365.4
BDBM50314417
Wt: 352.4
BDBM50314421
Wt: 341.4
BDBM50314423
Wt: 375.8
BDBM50314427
Wt: 409.4
BDBM50314428
Wt: 391.4
BDBM50314429
Wt: 369.4
BDBM50314430
Wt: 371.4
BDBM50314431
Wt: 369.4
BDBM50314432
Displayed 1 to 15 (of 23 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 32271,40169,42615,77203,83500,50302202,50314417,50314421,50314423,50314427,50314428,50314429,50314430,50314431,50314432   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apoptosis Regulator Bcl-xL


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/an/an/a 3.43E+3n/an/a7.44



NMMLSC

Curated by PubChem BioAssay


Assay Description
The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2K935WV
More data for this
Ligand-Target Pair
Inhibitor of NF-kappa-B kinase (IKK)


(Homo sapiens (Human))
BDBM50302202
PNG
(3-amino-4-(furan-2-yl)-6-methylthieno[2,3-b]pyridi...)
Show SMILES Cc1cc(-c2ccco2)c2c(N)c(sc2n1)C(N)=O
Show InChI InChI=1S/C13H11N3O2S/c1-6-5-7(8-3-2-4-18-8)9-10(14)11(12(15)17)19-13(9)16-6/h2-5H,14H2,1H3,(H2,15,17)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of Flag epitope-tagged IKK-beta preincubated for 5 mins by scintillation proximity assay


Bioorg Med Chem Lett 19: 5547-51 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.054
BindingDB Entry DOI: 10.7270/Q22Z16G1
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM40169
PNG
(3-Amino-4-furan-2-yl-6,7-dihydro-5H-cyclopenta[b]t...)
Show SMILES Cc1ccc(NC(=O)c2sc3nc4CCCc4c(-c4ccco4)c3c2N)cc1
Show InChI InChI=1S/C22H19N3O2S/c1-12-7-9-13(10-8-12)24-21(26)20-19(23)18-17(16-6-3-11-27-16)14-4-2-5-15(14)25-22(18)28-20/h3,6-11H,2,4-5,23H2,1H3,(H,24,26)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2QJ7FQ3
More data for this
Ligand-Target Pair
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/a>5.96E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769ZM
More data for this
Ligand-Target Pair
glutathione S-transferase


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/an/an/a 4.34E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2M61HPT
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 10


(Homo sapiens (Human))
BDBM42615
PNG
(3-amino-4-(2-furanyl)-5,6,7,8-tetrahydrothieno[2,3...)
Show SMILES Nc1c(sc2nc3CCCCc3c(-c3ccco3)c12)C#N
Show InChI InChI=1S/C16H13N3OS/c17-8-12-15(18)14-13(11-6-3-7-20-11)9-4-1-2-5-10(9)19-16(14)21-12/h3,6-7H,1-2,4-5,18H2
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n/an/a 6.86E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2KK996K
More data for this
Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B)


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/a 1.02E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2H993M3
More data for this
Ligand-Target Pair
POsterior Segregation family member (pos-1)


(Caenorhabditis elegans)
BDBM40169
PNG
(3-Amino-4-furan-2-yl-6,7-dihydro-5H-cyclopenta[b]t...)
Show SMILES Cc1ccc(NC(=O)c2sc3nc4CCCc4c(-c4ccco4)c3c2N)cc1
Show InChI InChI=1S/C22H19N3O2S/c1-12-7-9-13(10-8-12)24-21(26)20-19(23)18-17(16-6-3-11-27-16)14-4-2-5-15(14)25-22(18)28-20/h3,6-11H,2,4-5,23H2,1H3,(H,24,26)
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n/an/an/an/a 2.13E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q28G8J4C
More data for this
Ligand-Target Pair
RecName: Full=Zinc finger protein mex-5


(Caenorhabditis elegans)
BDBM40169
PNG
(3-Amino-4-furan-2-yl-6,7-dihydro-5H-cyclopenta[b]t...)
Show SMILES Cc1ccc(NC(=O)c2sc3nc4CCCc4c(-c4ccco4)c3c2N)cc1
Show InChI InChI=1S/C22H19N3O2S/c1-12-7-9-13(10-8-12)24-21(26)20-19(23)18-17(16-6-3-11-27-16)14-4-2-5-15(14)25-22(18)28-20/h3,6-11H,2,4-5,23H2,1H3,(H,24,26)
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n/an/an/an/a 2.85E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2D798VP
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77203
PNG
(3-amino-4-(2-furanyl)-N-(2-methylphenyl)-5,6,7,8-t...)
Show SMILES Cc1ccccc1NC(=O)c1sc2nc3CCCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C23H21N3O2S/c1-13-7-2-4-9-15(13)25-22(27)21-20(24)19-18(17-11-6-12-28-17)14-8-3-5-10-16(14)26-23(19)29-21/h2,4,6-7,9,11-12H,3,5,8,10,24H2,1H3,(H,25,27)
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n/an/an/an/a 1.01E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
mRNA interferase toxin, antitoxin is MazE


(Escherichia coli str. K-12 substr. MG1655)
BDBM83500
PNG
(3-Amino-4-furan-2-yl-6,7-dihydro-5H-cyclopenta[b]t...)
Show SMILES Nc1c(sc2nc3CCCc3c(-c3ccco3)c12)C(=O)Nc1ccccc1
Show InChI InChI=1S/C21H17N3O2S/c22-18-17-16(15-10-5-11-26-15)13-8-4-9-14(13)24-21(17)27-19(18)20(25)23-12-6-2-1-3-7-12/h1-3,5-7,10-11H,4,8-9,22H2,(H,23,25)
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n/an/an/an/a 1.13E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2Z31X54
More data for this
Ligand-Target Pair
mRNA interferase toxin, antitoxin is MazE


(Escherichia coli str. K-12 substr. MG1655)
BDBM83500
PNG
(3-Amino-4-furan-2-yl-6,7-dihydro-5H-cyclopenta[b]t...)
Show SMILES Nc1c(sc2nc3CCCc3c(-c3ccco3)c12)C(=O)Nc1ccccc1
Show InChI InChI=1S/C21H17N3O2S/c22-18-17-16(15-10-5-11-26-15)13-8-4-9-14(13)24-21(17)27-19(18)20(25)23-12-6-2-1-3-7-12/h1-3,5-7,10-11H,4,8-9,22H2,(H,23,25)
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n/an/an/an/a>9.90E+4n/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2TB15DB
More data for this
Ligand-Target Pair
Alpha trans-inducing protein (VP16)


(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/a 3.10E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2D21W6V
More data for this
Ligand-Target Pair
Nuclear receptor coactivator 1


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/a 3.29E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q28914F2
More data for this
Ligand-Target Pair
nuclear receptor coactivator 3 isoform a


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/a 1.12E+3n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2HT2MXV
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314417
PNG
(3-amino-4-m-tolyl-5,6,7,8,9,10-hexahydrocycloocta[...)
Show SMILES Cc1cccc(c1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C21H23N3OS/c1-12-7-6-8-13(11-12)16-14-9-4-2-3-5-10-15(14)24-21-17(16)18(22)19(26-21)20(23)25/h6-8,11H,2-5,9-10,22H2,1H3,(H2,23,25)
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n/an/a 1.20E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314421
PNG
(3-amino-4-(pyridin-3-yl)-5,6,7,8,9,10-hexahydrocyc...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3cccnc3)c2c1N
Show InChI InChI=1S/C19H20N4OS/c20-16-15-14(11-6-5-9-22-10-11)12-7-3-1-2-4-8-13(12)23-19(15)25-17(16)18(21)24/h5-6,9-10H,1-4,7-8,20H2,(H2,21,24)
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n/an/a 940n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314423
PNG
(3-amino-4-(furan-3-yl)-5,6,7,8,9,10-hexahydrocyclo...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccoc3)c2c1N
Show InChI InChI=1S/C18H19N3O2S/c19-15-14-13(10-7-8-23-9-10)11-5-3-1-2-4-6-12(11)21-18(14)24-16(15)17(20)22/h7-9H,1-6,19H2,(H2,20,22)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314427
PNG
(3-amino-4-(5-chlorofuran-2-yl)-5,6,7,8,9,10-hexahy...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(Cl)o3)c2c1N
Show InChI InChI=1S/C18H18ClN3O2S/c19-12-8-7-11(24-12)13-9-5-3-1-2-4-6-10(9)22-18-14(13)15(20)16(25-18)17(21)23/h7-8H,1-6,20H2,(H2,21,23)
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n/an/a 280n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314428
PNG
(3-amino-4-(5-(trifluoromethyl)furan-2-yl)-5,6,7,8,...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(o3)C(F)(F)F)c2c1N
Show InChI InChI=1S/C19H18F3N3O2S/c20-19(21,22)12-8-7-11(27-12)13-9-5-3-1-2-4-6-10(9)25-18-14(13)15(23)16(28-18)17(24)26/h7-8H,1-6,23H2,(H2,24,26)
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n/an/a 300n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314429
PNG
(3-amino-4-(benzofuran-2-yl)-5,6,7,8,9,10-hexahydro...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3cc4ccccc4o3)c2c1N
Show InChI InChI=1S/C22H21N3O2S/c23-19-18-17(16-11-12-7-5-6-10-15(12)27-16)13-8-3-1-2-4-9-14(13)25-22(18)28-20(19)21(24)26/h5-7,10-11H,1-4,8-9,23H2,(H2,24,26)
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n/an/a 330n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314430
PNG
(3-amino-4-(5-ethylfuran-2-yl)-5,6,7,8,9,10-hexahyd...)
Show SMILES CCc1ccc(o1)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C20H23N3O2S/c1-2-11-9-10-14(25-11)15-12-7-5-3-4-6-8-13(12)23-20-16(15)17(21)18(26-20)19(22)24/h9-10H,2-8,21H2,1H3,(H2,22,24)
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n/an/a 660n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314431
PNG
(3-amino-4-(5-(hydroxymethyl)furan-2-yl)-5,6,7,8,9,...)
Show SMILES NC(=O)c1sc2nc3CCCCCCc3c(-c3ccc(CO)o3)c2c1N
Show InChI InChI=1S/C19H21N3O3S/c20-16-15-14(13-8-7-10(9-23)25-13)11-5-3-1-2-4-6-12(11)22-19(15)26-17(16)18(21)24/h7-8,23H,1-6,9,20H2,(H2,21,24)
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n/an/a 800n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM50314432
PNG
(3-amino-4-(4,5-dimethylfuran-2-yl)-5,6,7,8,9,10-he...)
Show SMILES Cc1cc(oc1C)-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C20H23N3O2S/c1-10-9-14(25-11(10)2)15-12-7-5-3-4-6-8-13(12)23-20-16(15)17(21)18(26-20)19(22)24/h9H,3-8,21H2,1-2H3,(H2,22,24)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Myriad Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method


Bioorg Med Chem Lett 20: 2283-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.005
BindingDB Entry DOI: 10.7270/Q2F18ZVT
More data for this
Ligand-Target Pair
Focal adhesion kinase 1


(Homo sapiens (Human))
BDBM32271
PNG
(3-amino-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]th...)
Show SMILES NC(=O)c1sc2nc3CCCc3c(-c3ccco3)c2c1N
Show InChI InChI=1S/C15H13N3O2S/c16-12-11-10(9-5-2-6-20-9)7-3-1-4-8(7)18-15(11)21-13(12)14(17)19/h2,5-6H,1,3-4,16H2,(H2,17,19)
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n/an/a 1.19E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2GX48ZN
More data for this
Ligand-Target Pair