BindingDB logo
myBDB logout

26 similar compounds to monomer 50001591

Compile data set for download or QSAR
Wt: 370.3
BDBM36212
Purchase
Wt: 370.3
BDBM36213
Purchase
Wt: 370.3
BDBM36214
Purchase
Wt: 370.3
BDBM36215
Purchase
Wt: 370.3
BDBM36216
Wt: 370.3
BDBM36217
Wt: 370.3
BDBM36218
Wt: 370.3
BDBM36219
Wt: 386.3
BDBM36220
Wt: 386.3
BDBM36221
Wt: 386.3
BDBM36222
Wt: 386.3
BDBM36223
Wt: 414.5
BDBM50030347
Wt: 400.4
BDBM50030353
Wt: 414.5
BDBM50030357
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36212,36213,36214,36215,36216,36217,36218,36219,36220,36221,36222,36223,50030347,50030353,50030357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptidyl-glycine alpha-amidating monooxygenase


(Rattus norvegicus)
BDBM50030347
PNG
((R)-4-Mercapto-2-[(S)-3-phenyl-2-(3-phenyl-propion...)
Show SMILES OC(=O)[C@@H](CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccccc1
Show InChI InChI=1S/C22H26N2O4S/c25-20(12-11-16-7-3-1-4-8-16)23-19(15-17-9-5-2-6-10-17)21(26)24-18(13-14-29)22(27)28/h1-10,18-19,29H,11-15H2,(H,23,25)(H,24,26)(H,27,28)/t18-,19+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 610n/an/an/an/an/an/a



Ciba-Geigy Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against peptidylglycine alpha-amidating monooxygenase (PAM) was determined


J Med Chem 37: 4430-7 (1995)


Article DOI: 10.1021/jm00052a002
BindingDB Entry DOI: 10.7270/Q20R9NF9
More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Rattus norvegicus)
BDBM50030357
PNG
(4-Mercapto-2-[(S)-3-phenyl-2-(3-phenyl-propionylam...)
Show SMILES OC(=O)C(CCS)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccccc1
Show InChI InChI=1S/C22H26N2O4S/c25-20(12-11-16-7-3-1-4-8-16)23-19(15-17-9-5-2-6-10-17)21(26)24-18(13-14-29)22(27)28/h1-10,18-19,29H,11-15H2,(H,23,25)(H,24,26)(H,27,28)/t18?,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Ciba-Geigy Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against peptidylglycine alpha-amidating monooxygenase (PAM) was determined


J Med Chem 37: 4430-7 (1995)


Article DOI: 10.1021/jm00052a002
BindingDB Entry DOI: 10.7270/Q20R9NF9
More data for this
Ligand-Target Pair
Peptidyl-glycine alpha-amidating monooxygenase


(Rattus norvegicus)
BDBM50030353
PNG
((R)-3-Mercapto-2-[(S)-3-phenyl-2-(3-phenyl-propion...)
Show SMILES OC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccccc1
Show InChI InChI=1S/C21H24N2O4S/c24-19(12-11-15-7-3-1-4-8-15)22-17(13-16-9-5-2-6-10-16)20(25)23-18(14-28)21(26)27/h1-10,17-18,28H,11-14H2,(H,22,24)(H,23,25)(H,26,27)/t17-,18-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Ciba-Geigy Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against peptidylglycine alpha-amidating monooxygenase (PAM) was determined


J Med Chem 37: 4430-7 (1995)


Article DOI: 10.1021/jm00052a002
BindingDB Entry DOI: 10.7270/Q20R9NF9
More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 12 hits for monomerid = 36212,36213,36214,36215,36216,36217,36218,36219,36220,36221,36222,36223,50030347,50030353,50030357
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
BDBM36126
JPEG
BDBM36212
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-1.890.983-2.871.386.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36213
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-1.981.03-3.011.466.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36214
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.651.17-3.821.946.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36215
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.611.31-3.921.926.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36216
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.120.862-2.991.566.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36217
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.181.05-3.221.606.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36218
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.481.98-4.471.826.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36219
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.481.74-4.231.826.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36220
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.012.17-4.181.486.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36221
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.142.34-4.471.576.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36222
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.482.70-5.181.826.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)

BDBM36126
JPEG
BDBM36223
JPEG
CHEBI
MMDB
PC cid
PC sid
PDB
PC cid
PC sid
-2.522.44-4.941.856.9025



Japan Science and Technology Agency





J Org Chem 68: 5228-35 (2003)