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12 similar compounds to monomer 36342

Wt: 528.6
BDBM36336
Wt: 616.7
BDBM36337
Wt: 554.6
BDBM36338
Wt: 554.6
BDBM36339
Wt: 554.6
BDBM36340
Wt: 554.6
BDBM36341
Wt: 498.6
BDBM36343
Wt: 525.6
BDBM36344
Wt: 540.6
BDBM36345
Wt: 540.6
BDBM36346
Wt: 529.6
BDBM36347
Wt: 542.0
BDBM36348

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 36336,36337,36338,36339,36340,36341,36343,36344,36345,36346,36347,36348   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36336
PNG
(CID24762166 | Purfalcamine, 1)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1
Show InChI InChI=1S/C29H33FN8O/c30-20-5-4-6-24(17-20)38-18-32-25-26(35-29(36-27(25)38)34-23-13-9-21(31)10-14-23)33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H2,33,34,35,36)/t21-,23-
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n/an/a 17n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36348
PNG
((4-{9-(3-Chloro-phenyl)-2-[2-(3H-imidazol-4-yl)-et...)
Show SMILES Clc1cccc(c1)-n1cnc2c(Nc3ccc(cc3)C(=O)N3CCCCC3)nc(NCCc3cnc[nH]3)nc12
Show InChI InChI=1S/C28H28ClN9O/c29-20-5-4-6-23(15-20)38-18-33-24-25(35-28(36-26(24)38)31-12-11-22-16-30-17-32-22)34-21-9-7-19(8-10-21)27(39)37-13-2-1-3-14-37/h4-10,15-18H,1-3,11-14H2,(H,30,32)(H2,31,34,35,36)
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n/an/an/an/a 352n/an/a7.524



The Scripps Research Institute





Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36338
PNG
(CID24762168 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3ccc4OCOc4c3)c2n1
Show InChI InChI=1S/C30H34N8O3/c31-20-6-10-22(11-7-20)34-30-35-27(33-21-8-4-19(5-9-21)29(39)37-14-2-1-3-15-37)26-28(36-30)38(17-32-26)23-12-13-24-25(16-23)41-18-40-24/h4-5,8-9,12-13,16-17,20,22H,1-3,6-7,10-11,14-15,18,31H2,(H2,33,34,35,36)/t20-,22-
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n/an/a 342n/an/an/an/a7.524



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Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36339
PNG
(3-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperid...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(c3)C(O)=O)c2n1
Show InChI InChI=1S/C30H34N8O3/c31-21-9-13-23(14-10-21)34-30-35-26(33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37)25-27(36-30)38(18-32-25)24-6-4-5-20(17-24)29(40)41/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H,40,41)(H2,33,34,35,36)/t21-,23-
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n/an/a 71n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36340
PNG
(4-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperid...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3ccc(cc3)C(O)=O)c2n1
Show InChI InChI=1S/C30H34N8O3/c31-21-8-12-23(13-9-21)34-30-35-26(33-22-10-4-19(5-11-22)28(39)37-16-2-1-3-17-37)25-27(36-30)38(18-32-25)24-14-6-20(7-15-24)29(40)41/h4-7,10-11,14-15,18,21,23H,1-3,8-9,12-13,16-17,31H2,(H,40,41)(H2,33,34,35,36)/t21-,23-
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n/an/a 28n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36341
PNG
(CID24762171 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES CCOc1ccc(cc1)-n1cnc2c(Nc3ccc(cc3)C(=O)N3CCCCC3)nc(N[C@H]3CC[C@H](N)CC3)nc12
Show InChI InChI=1S/C31H38N8O2/c1-2-41-26-16-14-25(15-17-26)39-20-33-27-28(36-31(37-29(27)39)35-24-12-8-22(32)9-13-24)34-23-10-6-21(7-11-23)30(40)38-18-4-3-5-19-38/h6-7,10-11,14-17,20,22,24H,2-5,8-9,12-13,18-19,32H2,1H3,(H2,34,35,36,37)/t22-,24-
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n/an/a 240n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36343
PNG
(CID24762173 | N2-trans-(4-Amino-cyclohexyl)-N6-(4-...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(CN3CCOCC3)cc2)c2ncn(-c3ccccc3)c2n1
Show InChI InChI=1S/C28H34N8O/c29-21-8-12-23(13-9-21)32-28-33-26(25-27(34-28)36(19-30-25)24-4-2-1-3-5-24)31-22-10-6-20(7-11-22)18-35-14-16-37-17-15-35/h1-7,10-11,19,21,23H,8-9,12-18,29H2,(H2,31,32,33,34)/t21-,23-
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n/an/a 703n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36344
PNG
(CID24762174 | {3-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES CN1CCN(CC1)C(=O)c1cccc(Nc2nc(N[C@H]3CC[C@H](N)CC3)nc3n(cnc23)-c2ccccc2)c1
Show InChI InChI=1S/C29H35N9O/c1-36-14-16-37(17-15-36)28(39)20-6-5-7-23(18-20)32-26-25-27(38(19-31-25)24-8-3-2-4-9-24)35-29(34-26)33-22-12-10-21(30)11-13-22/h2-9,18-19,21-22H,10-17,30H2,1H3,(H2,32,33,34,35)/t21-,22-
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n/an/a 6.87E+3n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36345
PNG
(CID24762175 | {4-[2-(3-Morpholin-4-yl-propylamino)...)
Show SMILES O=C(N1CCCCC1)c1ccc(Nc2nc(NCCCN3CCOCC3)nc3n(cnc23)-c2ccccc2)cc1
Show InChI InChI=1S/C30H36N8O2/c39-29(37-16-5-2-6-17-37)23-10-12-24(13-11-23)33-27-26-28(38(22-32-26)25-8-3-1-4-9-25)35-30(34-27)31-14-7-15-36-18-20-40-21-19-36/h1,3-4,8-13,22H,2,5-7,14-21H2,(H2,31,33,34,35)
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n/an/a 430n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36346
PNG
(CID24762176 | {4-[9-Phenyl-2-(quinolin-3-ylamino)-...)
Show SMILES O=C(N1CCCCC1)c1ccc(Nc2nc(Nc3cnc4ccccc4c3)nc3n(cnc23)-c2ccccc2)cc1
Show InChI InChI=1S/C32H28N8O/c41-31(39-17-7-2-8-18-39)22-13-15-24(16-14-22)35-29-28-30(40(21-34-28)26-10-3-1-4-11-26)38-32(37-29)36-25-19-23-9-5-6-12-27(23)33-20-25/h1,3-6,9-16,19-21H,2,7-8,17-18H2,(H2,35,36,37,38)
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n/an/a 3.85E+3n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36347
PNG
(CID24762177 | {4-[9-(3-Fluoro-phenyl)-2-trans-(4-h...)
Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1
Show InChI InChI=1S/C29H32FN7O2/c30-20-5-4-6-23(17-20)37-18-31-25-26(34-29(35-27(25)37)33-22-11-13-24(38)14-12-22)32-21-9-7-19(8-10-21)28(39)36-15-2-1-3-16-36/h4-10,17-18,22,24,38H,1-3,11-16H2,(H2,32,33,34,35)/t22-,24-
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n/an/a 150n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36348
PNG
((4-{9-(3-Chloro-phenyl)-2-[2-(3H-imidazol-4-yl)-et...)
Show SMILES Clc1cccc(c1)-n1cnc2c(Nc3ccc(cc3)C(=O)N3CCCCC3)nc(NCCc3cnc[nH]3)nc12
Show InChI InChI=1S/C28H28ClN9O/c29-20-5-4-6-23(15-20)38-18-33-24-25(35-28(36-26(24)38)31-12-11-22-16-30-17-32-22)34-21-9-7-19(8-10-21)27(39)37-13-2-1-3-14-37/h4-10,15-18H,1-3,11-14H2,(H,30,32)(H2,31,34,35,36)
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n/an/a 626n/an/an/an/a7.524



The Scripps Research Institute



Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36336
PNG
(CID24762166 | Purfalcamine, 1)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1
Show InChI InChI=1S/C29H33FN8O/c30-20-5-4-6-24(17-20)38-18-32-25-26(35-29(36-27(25)38)34-23-13-9-21(31)10-14-23)33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H2,33,34,35,36)/t21-,23-
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n/an/an/an/a 230n/an/a7.524



The Scripps Research Institute





Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36336
PNG
(CID24762166 | Purfalcamine, 1)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1
Show InChI InChI=1S/C29H33FN8O/c30-20-5-4-6-24(17-20)38-18-32-25-26(35-29(36-27(25)38)34-23-13-9-21(31)10-14-23)33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H2,33,34,35,36)/t21-,23-
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n/an/an/an/a 230n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36337
PNG
(CID24762167 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES NC1CCC(CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(OCc4ccccc4)c3)c2n1
Show InChI InChI=1S/C36H40N8O2/c37-27-14-18-29(19-15-27)40-36-41-33(39-28-16-12-26(13-17-28)35(45)43-20-5-2-6-21-43)32-34(42-36)44(24-38-32)30-10-7-11-31(22-30)46-23-25-8-3-1-4-9-25/h1,3-4,7-13,16-17,22,24,27,29H,2,5-6,14-15,18-21,23,37H2,(H2,39,40,41,42)
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n/an/an/an/a 312n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36338
PNG
(CID24762168 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3ccc4OCOc4c3)c2n1
Show InChI InChI=1S/C30H34N8O3/c31-20-6-10-22(11-7-20)34-30-35-27(33-21-8-4-19(5-9-21)29(39)37-14-2-1-3-15-37)26-28(36-30)38(17-32-26)23-12-13-24-25(16-23)41-18-40-24/h4-5,8-9,12-13,16-17,20,22H,1-3,6-7,10-11,14-15,18,31H2,(H2,33,34,35,36)/t20-,22-
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n/an/an/an/a 400n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36339
PNG
(3-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperid...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(c3)C(O)=O)c2n1
Show InChI InChI=1S/C30H34N8O3/c31-21-9-13-23(14-10-21)34-30-35-26(33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37)25-27(36-30)38(18-32-25)24-6-4-5-20(17-24)29(40)41/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H,40,41)(H2,33,34,35,36)/t21-,23-
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n/an/an/an/a>1.00E+4n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36340
PNG
(4-{2-trans-(4-Amino-cyclohexylamino)-6-[4-(piperid...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3ccc(cc3)C(O)=O)c2n1
Show InChI InChI=1S/C30H34N8O3/c31-21-8-12-23(13-9-21)34-30-35-26(33-22-10-4-19(5-11-22)28(39)37-16-2-1-3-17-37)25-27(36-30)38(18-32-25)24-14-6-20(7-15-24)29(40)41/h4-7,10-11,14-15,18,21,23H,1-3,8-9,12-13,16-17,31H2,(H,40,41)(H2,33,34,35,36)/t21-,23-
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n/an/an/an/a>1.00E+4n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36341
PNG
(CID24762171 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES CCOc1ccc(cc1)-n1cnc2c(Nc3ccc(cc3)C(=O)N3CCCCC3)nc(N[C@H]3CC[C@H](N)CC3)nc12
Show InChI InChI=1S/C31H38N8O2/c1-2-41-26-16-14-25(15-17-26)39-20-33-27-28(36-31(37-29(27)39)35-24-12-8-22(32)9-13-24)34-23-10-6-21(7-11-23)30(40)38-18-4-3-5-19-38/h6-7,10-11,14-17,20,22,24H,2-5,8-9,12-13,18-19,32H2,1H3,(H2,34,35,36,37)/t22-,24-
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n/an/an/an/a 535n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36343
PNG
(CID24762173 | N2-trans-(4-Amino-cyclohexyl)-N6-(4-...)
Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(CN3CCOCC3)cc2)c2ncn(-c3ccccc3)c2n1
Show InChI InChI=1S/C28H34N8O/c29-21-8-12-23(13-9-21)32-28-33-26(25-27(34-28)36(19-30-25)24-4-2-1-3-5-24)31-22-10-6-20(7-11-22)18-35-14-16-37-17-15-35/h1-7,10-11,19,21,23H,8-9,12-18,29H2,(H2,31,32,33,34)/t21-,23-
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n/an/an/an/a 174n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36344
PNG
(CID24762174 | {3-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES CN1CCN(CC1)C(=O)c1cccc(Nc2nc(N[C@H]3CC[C@H](N)CC3)nc3n(cnc23)-c2ccccc2)c1
Show InChI InChI=1S/C29H35N9O/c1-36-14-16-37(17-15-36)28(39)20-6-5-7-23(18-20)32-26-25-27(38(19-31-25)24-8-3-2-4-9-24)35-29(34-26)33-22-12-10-21(30)11-13-22/h2-9,18-19,21-22H,10-17,30H2,1H3,(H2,32,33,34,35)/t21-,22-
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n/an/an/an/a 1.30E+3n/an/a7.524



The Scripps Research Institute





Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36345
PNG
(CID24762175 | {4-[2-(3-Morpholin-4-yl-propylamino)...)
Show SMILES O=C(N1CCCCC1)c1ccc(Nc2nc(NCCCN3CCOCC3)nc3n(cnc23)-c2ccccc2)cc1
Show InChI InChI=1S/C30H36N8O2/c39-29(37-16-5-2-6-17-37)23-10-12-24(13-11-23)33-27-26-28(38(22-32-26)25-8-3-1-4-9-25)35-30(34-27)31-14-7-15-36-18-20-40-21-19-36/h1,3-4,8-13,22H,2,5-7,14-21H2,(H2,31,33,34,35)
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n/an/an/an/a 2.99E+3n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36346
PNG
(CID24762176 | {4-[9-Phenyl-2-(quinolin-3-ylamino)-...)
Show SMILES O=C(N1CCCCC1)c1ccc(Nc2nc(Nc3cnc4ccccc4c3)nc3n(cnc23)-c2ccccc2)cc1
Show InChI InChI=1S/C32H28N8O/c41-31(39-17-7-2-8-18-39)22-13-15-24(16-14-22)35-29-28-30(40(21-34-28)26-10-3-1-4-11-26)38-32(37-29)36-25-19-23-9-5-6-12-27(23)33-20-25/h1,3-6,9-16,19-21H,2,7-8,17-18H2,(H2,35,36,37,38)
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n/an/an/an/a 101n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36347
PNG
(CID24762177 | {4-[9-(3-Fluoro-phenyl)-2-trans-(4-h...)
Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1
Show InChI InChI=1S/C29H32FN7O2/c30-20-5-4-6-23(17-20)37-18-31-25-26(34-29(35-27(25)37)33-22-11-13-24(38)14-12-22)32-21-9-7-19(8-10-21)28(39)36-15-2-1-3-16-36/h4-10,17-18,22,24,38H,1-3,11-16H2,(H2,32,33,34,35)/t22-,24-
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n/an/an/an/a>1.00E+4n/an/a7.524



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Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair
Calcium-dependent protein kinase 1


(Plasmodium Falciparum)
BDBM36337
PNG
(CID24762167 | {4-[2-trans-(4-Amino-cyclohexylamino...)
Show SMILES NC1CCC(CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(OCc4ccccc4)c3)c2n1
Show InChI InChI=1S/C36H40N8O2/c37-27-14-18-29(19-15-27)40-36-41-33(39-28-16-12-26(13-17-28)35(45)43-20-5-2-6-21-43)32-34(42-36)44(24-38-32)30-10-7-11-31(22-30)46-23-25-8-3-1-4-9-25/h1,3-4,7-13,16-17,22,24,27,29H,2,5-6,14-15,18-21,23,37H2,(H2,39,40,41,42)
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Assay Description
The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...


Nat Chem Biol 4: 347-56 (2008)

More data for this
Ligand-Target Pair