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4 similar compounds to monomer 93781

Wt: 247.2
BDBM49538
Wt: 265.2
BDBM49562
Wt: 247.2
BDBM49573
Wt: 247.2
BDBM114736

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 49538,49562,49573,114736   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM49538
PNG
((Z)-3-(3-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1cccc(c1)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-3-1-4-11(9-10)15-7-6-12(16)13-5-2-8-17-13/h1-5,7-9H,6H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 347n/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM49562
PNG
((E)-3-(3,4-difluoroanilino)-1-(2-thienyl)prop-2-en...)
Show SMILES Fc1ccc(cc1F)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H9F2NOS/c14-10-4-3-9(8-11(10)15)16-6-5-12(17)13-2-1-7-18-13/h1-4,6-8H,5H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 963n/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Nuclear factor NF-kappa-B


(Homo sapiens (Human))
BDBM49573
PNG
((E)-3-(2-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccccc1N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-4-1-2-5-11(10)15-8-7-12(16)13-6-3-9-17-13/h1-6,8-9H,7H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 413n/an/an/an/a



SRMLSC

Curated by PubChem BioAssay


Assay Description
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
SKiNhead family member (skn-1)


(Caenorhabditis elegans)
BDBM49538
PNG
((Z)-3-(3-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1cccc(c1)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-3-1-4-11(9-10)15-7-6-12(16)13-5-2-8-17-13/h1-5,7-9H,6H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a 4.67E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
SKiNhead family member (skn-1)


(Caenorhabditis elegans)
BDBM49562
PNG
((E)-3-(3,4-difluoroanilino)-1-(2-thienyl)prop-2-en...)
Show SMILES Fc1ccc(cc1F)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H9F2NOS/c14-10-4-3-9(8-11(10)15)16-6-5-12(17)13-2-1-7-18-13/h1-4,6-8H,5H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a 1.14E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
SKiNhead family member (skn-1)


(Caenorhabditis elegans)
BDBM49573
PNG
((E)-3-(2-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccccc1N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-4-1-2-5-11(10)15-8-7-12(16)13-6-3-9-17-13/h1-6,8-9H,7H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a 2.79E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
Protein DAF-12, isoform a


(Caenorhabditis elegans)
BDBM49573
PNG
((E)-3-(2-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccccc1N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-4-1-2-5-11(10)15-8-7-12(16)13-6-3-9-17-13/h1-6,8-9H,7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a 6.76E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)

More data for this
Ligand-Target Pair
Protein HSP-16.2


(Caenorhabditis elegans)
BDBM49573
PNG
((E)-3-(2-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccccc1N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-4-1-2-5-11(10)15-8-7-12(16)13-6-3-9-17-13/h1-6,8-9H,7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a>6.40E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)

More data for this
Ligand-Target Pair
Liver X receptor beta (LXRB)


(Homo sapiens (Human))
BDBM49538
PNG
((Z)-3-(3-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1cccc(c1)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-3-1-4-11(9-10)15-7-6-12(16)13-5-2-8-17-13/h1-5,7-9H,6H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 6.75E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)

More data for this
Ligand-Target Pair
Liver X receptor beta (LXRB)


(Homo sapiens (Human))
BDBM114736
PNG
((E)-3-(4-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccc(cc1)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-3-5-11(6-4-10)15-8-7-12(16)13-2-1-9-17-13/h1-6,8-9H,7H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 6.76E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)

More data for this
Ligand-Target Pair
Protein DAF-12, isoform a


(Caenorhabditis elegans)
BDBM49538
PNG
((Z)-3-(3-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1cccc(c1)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-3-1-4-11(9-10)15-7-6-12(16)13-5-2-8-17-13/h1-5,7-9H,6H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 6.75E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2013)

More data for this
Ligand-Target Pair
Protein DAF-12, isoform a


(Caenorhabditis elegans)
BDBM114736
PNG
((E)-3-(4-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccc(cc1)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-3-5-11(6-4-10)15-8-7-12(16)13-2-1-9-17-13/h1-6,8-9H,7H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/an/an/a 6.76E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2013)

More data for this
Ligand-Target Pair
Liver X receptor beta (LXRB)


(Homo sapiens (Human))
BDBM49573
PNG
((E)-3-(2-fluoroanilino)-1-(2-thienyl)prop-2-en-1-o...)
Show SMILES Fc1ccccc1N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H10FNOS/c14-10-4-1-2-5-11(10)15-8-7-12(16)13-6-3-9-17-13/h1-6,8-9H,7H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a 6.76E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...


PubChem Bioassay (2013)

More data for this
Ligand-Target Pair
Protein HSP-16.2


(Caenorhabditis elegans)
BDBM49562
PNG
((E)-3-(3,4-difluoroanilino)-1-(2-thienyl)prop-2-en...)
Show SMILES Fc1ccc(cc1F)N=CCC(=O)c1cccs1
Show InChI InChI=1S/C13H9F2NOS/c14-10-4-3-9(8-11(10)15)16-6-5-12(17)13-2-1-7-18-13/h1-4,6-8H,5H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PCBioAssay
n/an/a>6.40E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)

More data for this
Ligand-Target Pair