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13 similar compounds to monomer 50190528

Compile data set for download or QSAR
Wt: 475.6
BDBM50002421
Wt: 447.6
BDBM50002427
Wt: 529.5
BDBM50002437
Wt: 475.6
BDBM50002416
Wt: 461.5
BDBM50002433
Wt: 479.5
BDBM50002434
Wt: 461.5
BDBM50002438
Wt: 529.5
BDBM50002412
Wt: 475.6
BDBM50002429
Wt: 475.6
BDBM50002415
Wt: 475.6
BDBM50002430
Wt: 497.5
BDBM50372611
Wt: 479.5
BDBM50416839

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50002421,50002427,50002437,50002416,50002433,50002434,50002438,50002412,50002429,50002415,50002430,50372611,50416839   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oxytocin receptor


(HEK293)
BDBM50372611
PNG
(CHEMBL196478)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H33F2N3O3/c1-15(2)11-23-26(34)32-24(19-12-17-7-5-6-8-18(17)13-19)28(36)33(23)25(27(35)31-16(3)4)21-10-9-20(29)14-22(21)30/h5-10,14-16,19,23-25H,11-13H2,1-4H3,(H,31,35)(H,32,34)/t23-,24-,25-/m1/s1
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1.26n/an/an/an/an/an/an/an/a



DrugMolDesign

Curated by ChEMBL


Assay Description
Displacement of [3H]-oxytocin from human oxytocin receptor


J Med Chem 53: 6525-38 (2010)


Article DOI: 10.1021/jm901812z
BindingDB Entry DOI: 10.7270/Q20R9PMZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50416839
PNG
(CHEMBL197793)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25-/m1/s1
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3.98n/an/an/an/an/an/an/an/a



DrugMolDesign

Curated by ChEMBL


Assay Description
Displacement of [3H]-oxytocin from human oxytocin receptor


J Med Chem 53: 6525-38 (2010)


Article DOI: 10.1021/jm901812z
BindingDB Entry DOI: 10.7270/Q20R9PMZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002438
PNG
(CHEMBL382518)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccccc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H35N3O3/c1-17(2)14-23-26(32)30-24(22-15-20-12-8-9-13-21(20)16-22)28(34)31(23)25(27(33)29-18(3)4)19-10-6-5-7-11-19/h5-13,17-18,22-25H,14-16H2,1-4H3,(H,29,33)(H,30,32)/t23-,24-,25-/m1/s1
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4n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002430
PNG
(CHEMBL372978)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)N(C)C(C)C)c2ccccc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H37N3O3/c1-18(2)15-24-27(33)30-25(23-16-21-13-9-10-14-22(21)17-23)28(34)32(24)26(20-11-7-6-8-12-20)29(35)31(5)19(3)4/h6-14,18-19,23-26H,15-17H2,1-5H3,(H,30,33)/t24-,25-,26-/m1/s1
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4n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002421
PNG
(CHEMBL555148)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(C)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H37N3O3/c1-17(2)14-24-27(33)31-25(23-15-21-8-6-7-9-22(21)16-23)29(35)32(24)26(28(34)30-18(3)4)20-12-10-19(5)11-13-20/h6-13,17-18,23-26H,14-16H2,1-5H3,(H,30,34)(H,31,33)/t24-,25-,26-/m1/s1
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4n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50416839
PNG
(CHEMBL197793)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25-/m1/s1
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4n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002416
PNG
(CHEMBL194374)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)(C)C)c2ccccc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H37N3O3/c1-18(2)15-23-26(33)30-24(22-16-20-13-9-10-14-21(20)17-22)28(35)32(23)25(19-11-7-6-8-12-19)27(34)31-29(3,4)5/h6-14,18,22-25H,15-17H2,1-5H3,(H,30,33)(H,31,34)/t23-,24-,25-/m1/s1
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5n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002412
PNG
(CHEMBL198329)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(cc2)C(F)(F)F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H34F3N3O3/c1-16(2)13-23-26(36)34-24(21-14-19-7-5-6-8-20(19)15-21)28(38)35(23)25(27(37)33-17(3)4)18-9-11-22(12-10-18)29(30,31)32/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,33,37)(H,34,36)/t23-,24-,25-/m1/s1
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5n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002429
PNG
(CHEMBL194922)
Show SMILES CC(C)C[C@H]1N([C@H](C(=O)NC(C)C)c2ccc(C)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H37N3O3/c1-17(2)14-24-27(33)31-25(23-15-21-8-6-7-9-22(21)16-23)29(35)32(24)26(28(34)30-18(3)4)20-12-10-19(5)11-13-20/h6-13,17-18,23-26H,14-16H2,1-5H3,(H,30,34)(H,31,33)/t24-,25-,26+/m1/s1
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50n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002433
PNG
(CHEMBL273988)
Show SMILES CC(C)C[C@H]1N([C@H](C(=O)NC(C)C)c2ccccc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H35N3O3/c1-17(2)14-23-26(32)30-24(22-15-20-12-8-9-13-21(20)16-22)28(34)31(23)25(27(33)29-18(3)4)19-10-6-5-7-11-19/h5-13,17-18,22-25H,14-16H2,1-4H3,(H,29,33)(H,30,32)/t23-,24-,25+/m1/s1
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50n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002415
PNG
(CHEMBL198328)
Show SMILES CC(C)C[C@H]1N([C@H](C(=O)NC(C)(C)C)c2ccccc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H37N3O3/c1-18(2)15-23-26(33)30-24(22-16-20-13-9-10-14-21(20)17-22)28(35)32(23)25(19-11-7-6-8-12-19)27(34)31-29(3,4)5/h6-14,18,22-25H,15-17H2,1-5H3,(H,30,33)(H,31,34)/t23-,24-,25+/m1/s1
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79n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002437
PNG
(CHEMBL194233)
Show SMILES CC(C)C[C@H]1N([C@H](C(=O)NC(C)C)c2ccc(cc2)C(F)(F)F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C29H34F3N3O3/c1-16(2)13-23-26(36)34-24(21-14-19-7-5-6-8-20(19)15-21)28(38)35(23)25(27(37)33-17(3)4)18-9-11-22(12-10-18)29(30,31)32/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,33,37)(H,34,36)/t23-,24-,25+/m1/s1
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79n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002434
PNG
(CHEMBL427353)
Show SMILES CC(C)C[C@H]1N([C@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25+/m1/s1
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100n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50002427
PNG
(CHEMBL194431)
Show SMILES CC(C)C[C@@H]1CN[C@H](C2Cc3ccccc3C2)C(=O)N1[C@@H](C(=O)NC(C)C)c1ccccc1
Show InChI InChI=1S/C28H37N3O2/c1-18(2)14-24-17-29-25(23-15-21-12-8-9-13-22(21)16-23)28(33)31(24)26(27(32)30-19(3)4)20-10-6-5-7-11-20/h5-13,18-19,23-26,29H,14-17H2,1-4H3,(H,30,32)/t24-,25-,26-/m1/s1
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316n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human Oxytocin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50372611
PNG
(CHEMBL196478)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H33F2N3O3/c1-15(2)11-23-26(34)32-24(19-12-17-7-5-6-8-18(17)13-19)28(36)33(23)25(27(35)31-16(3)4)21-10-9-20(29)14-22(21)30/h5-10,14-16,19,23-25H,11-13H2,1-4H3,(H,31,35)(H,32,34)/t23-,24-,25-/m1/s1
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631n/an/an/an/an/an/an/an/a



DrugMolDesign

Curated by ChEMBL


Assay Description
Displacement of [3H]vasopressin from human vasopressin V2 receptor


J Med Chem 53: 6525-38 (2010)


Article DOI: 10.1021/jm901812z
BindingDB Entry DOI: 10.7270/Q20R9PMZ
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50372611
PNG
(CHEMBL196478)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H33F2N3O3/c1-15(2)11-23-26(34)32-24(19-12-17-7-5-6-8-18(17)13-19)28(36)33(23)25(27(35)31-16(3)4)21-10-9-20(29)14-22(21)30/h5-10,14-16,19,23-25H,11-13H2,1-4H3,(H,31,35)(H,32,34)/t23-,24-,25-/m1/s1
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631n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human V2 vasopressin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50416839
PNG
(CHEMBL197793)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25-/m1/s1
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1.26E+3n/an/an/an/an/an/an/an/a



DrugMolDesign

Curated by ChEMBL


Assay Description
Displacement of [3H]vasopressin from human vasopressin V2 receptor


J Med Chem 53: 6525-38 (2010)


Article DOI: 10.1021/jm901812z
BindingDB Entry DOI: 10.7270/Q20R9PMZ
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50416839
PNG
(CHEMBL197793)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25-/m1/s1
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<1.26E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human V2 vasopressin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Vasopressin V1b receptor


(Homo sapiens (Human))
BDBM50416839
PNG
(CHEMBL197793)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25-/m1/s1
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<6.31E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human V1b vasopressin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50416839
PNG
(CHEMBL197793)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H34FN3O3/c1-16(2)13-23-26(33)31-24(21-14-19-7-5-6-8-20(19)15-21)28(35)32(23)25(27(34)30-17(3)4)18-9-11-22(29)12-10-18/h5-12,16-17,21,23-25H,13-15H2,1-4H3,(H,30,34)(H,31,33)/t23-,24-,25-/m1/s1
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<6.31E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human V1a vasopressin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50372611
PNG
(CHEMBL196478)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H33F2N3O3/c1-15(2)11-23-26(34)32-24(19-12-17-7-5-6-8-18(17)13-19)28(36)33(23)25(27(35)31-16(3)4)21-10-9-20(29)14-22(21)30/h5-10,14-16,19,23-25H,11-13H2,1-4H3,(H,31,35)(H,32,34)/t23-,24-,25-/m1/s1
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<6.31E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human V1a vasopressin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Vasopressin V1b receptor


(Homo sapiens (Human))
BDBM50372611
PNG
(CHEMBL196478)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H33F2N3O3/c1-15(2)11-23-26(34)32-24(19-12-17-7-5-6-8-18(17)13-19)28(36)33(23)25(27(35)31-16(3)4)21-10-9-20(29)14-22(21)30/h5-10,14-16,19,23-25H,11-13H2,1-4H3,(H,31,35)(H,32,34)/t23-,24-,25-/m1/s1
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<6.31E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human V1b vasopressin receptor


J Med Chem 48: 6956-69 (2005)

Checked by Author
Article DOI: 10.1021/jm050557v
BindingDB Entry DOI: 10.7270/Q2TX3GWZ
More data for this
Ligand-Target Pair
Cytochrome P450 3A


(Homo sapiens (Human))
BDBM50372611
PNG
(CHEMBL196478)
Show SMILES CC(C)C[C@H]1N([C@@H](C(=O)NC(C)C)c2ccc(F)cc2F)C(=O)[C@H](NC1=O)C1Cc2ccccc2C1
Show InChI InChI=1S/C28H33F2N3O3/c1-15(2)11-23-26(34)32-24(19-12-17-7-5-6-8-18(17)13-19)28(36)33(23)25(27(35)31-16(3)4)21-10-9-20(29)14-22(21)30/h5-10,14-16,19,23-25H,11-13H2,1-4H3,(H,31,35)(H,32,34)/t23-,24-,25-/m1/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Inhibition of CYP3A4


Bioorg Med Chem Lett 18: 90-4 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.008
BindingDB Entry DOI: 10.7270/Q2XD12H2
More data for this
Ligand-Target Pair