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55 similar compounds to monomer 50040761

Compile data set for download or QSAR
Wt: 621.7
BDBM50003321
Wt: 950.0
BDBM50003323
Wt: 648.7
BDBM50010175
Wt: 591.6
BDBM50010176
Wt: 678.7
BDBM50010187
Wt: 676.7
BDBM50010177
Wt: 619.7
BDBM50010171
Wt: 633.7
BDBM50010161
Wt: 591.7
BDBM50010166
Wt: 661.7
BDBM50010193
Wt: 633.7
BDBM50010162
Wt: 633.7
BDBM50010183
Wt: 675.8
BDBM50040735
Wt: 591.7
BDBM50040752
Wt: 633.7
BDBM50040762
Displayed 1 to 15 (of 54 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50003321,50003323,50010175,50010176,50010187,50010177,50010171,50010161,50010166,50010193,50010162,50010183,50040735,50040752,50040762   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50040752
PNG
(CHEMBL2371457 | [(7S,13S,16R)-16-Amino-4-carbamoyl...)
Show SMILES CN1[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@H](N)C1=O
Show InChI InChI=1S/C21H37N9O7S2/c1-21(2)15(16(23)34)29-17(35)11(7-14(32)33)28-13(31)8-27-18(36)12(5-4-6-26-20(24)25)30(3)19(37)10(22)9-38-39-21/h10-12,15H,4-9,22H2,1-3H3,(H2,23,34)(H,27,36)(H,28,31)(H,29,35)(H,32,33)(H4,24,25,26)/t10-,11-,12-,15-/m0/s1
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9.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes


J Med Chem 37: 769-80 (1994)


Article DOI: 10.1021/jm00032a009
BindingDB Entry DOI: 10.7270/Q2445KJB
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50040735
PNG
(CHEMBL2371469 | [(7S,13S,16R)-4-Carbamoyl-13-(3-gu...)
Show SMILES CCCCC(=O)N[C@H]1CSSC(C)(C)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)N(C)C1=O)C(N)=O
Show InChI InChI=1S/C26H45N9O8S2/c1-5-6-9-17(36)33-15-13-44-45-26(2,3)20(21(27)40)34-22(41)14(11-19(38)39)32-18(37)12-31-23(42)16(35(4)24(15)43)8-7-10-30-25(28)29/h14-16,20H,5-13H2,1-4H3,(H2,27,40)(H,31,42)(H,32,37)(H,33,36)(H,34,41)(H,38,39)(H4,28,29,30)/t14-,15-,16-,20-/m0/s1
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26n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes


J Med Chem 37: 769-80 (1994)


Article DOI: 10.1021/jm00032a009
BindingDB Entry DOI: 10.7270/Q2445KJB
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010161
PNG
(CHEMBL2370397 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES CN1[C@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O
Show InChI InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,39)(H,29,33)(H,30,34)(H,31,38)(H,35,36)(H4,25,26,27)/t12-,13-,14-,17+/m1/s1
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58n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50040762
PNG
(CHEMBL2371456 | [(7S,13S,16R)-16-Acetylamino-4-car...)
Show SMILES CN1[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@H](NC(C)=O)C1=O
Show InChI InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,39)(H,29,33)(H,30,34)(H,31,38)(H,35,36)(H4,25,26,27)/t12-,13-,14-,17-/m0/s1
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58n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes


J Med Chem 37: 769-80 (1994)


Article DOI: 10.1021/jm00032a009
BindingDB Entry DOI: 10.7270/Q2445KJB
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010161
PNG
(CHEMBL2370397 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES CN1[C@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O
Show InChI InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,39)(H,29,33)(H,30,34)(H,31,38)(H,35,36)(H4,25,26,27)/t12-,13-,14-,17+/m1/s1
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62n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50040762
PNG
(CHEMBL2371456 | [(7S,13S,16R)-16-Acetylamino-4-car...)
Show SMILES CN1[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@H](NC(C)=O)C1=O
Show InChI InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,39)(H,29,33)(H,30,34)(H,31,38)(H,35,36)(H4,25,26,27)/t12-,13-,14-,17-/m0/s1
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102n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SKF- 107260 binding to purified GPIIb/IIIa from human platelets reconstituted in liposomes


J Med Chem 37: 769-80 (1994)


Article DOI: 10.1021/jm00032a009
BindingDB Entry DOI: 10.7270/Q2445KJB
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010176
PNG
(CHEMBL107009 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C20H33N9O8S2/c1-9(30)26-13-8-39-38-7-12(16(21)34)29-18(36)11(5-15(32)33)27-14(31)6-25-17(35)10(28-19(13)37)3-2-4-24-20(22)23/h10-13H,2-8H2,1H3,(H2,21,34)(H,25,35)(H,26,30)(H,27,31)(H,28,37)(H,29,36)(H,32,33)(H4,22,23,24)/t10-,11-,12-,13-/m1/s1
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780n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomes


J Med Chem 37: 769-80 (1994)


Article DOI: 10.1021/jm00032a009
BindingDB Entry DOI: 10.7270/Q2445KJB
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010176
PNG
(CHEMBL107009 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C20H33N9O8S2/c1-9(30)26-13-8-39-38-7-12(16(21)34)29-18(36)11(5-15(32)33)27-14(31)6-25-17(35)10(28-19(13)37)3-2-4-24-20(22)23/h10-13H,2-8H2,1H3,(H2,21,34)(H,25,35)(H,26,30)(H,27,31)(H,28,37)(H,29,36)(H,32,33)(H4,22,23,24)/t10-,11-,12-,13-/m1/s1
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780n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003321
PNG
(3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...)
Show SMILES CC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(N)=O)C(C)(C)S
Show InChI InChI=1S/C22H39N9O8S2/c1-10(32)28-13(9-40)20(39)30-11(5-4-6-26-21(24)25)18(37)27-8-14(33)29-12(7-15(34)35)19(38)31-16(17(23)36)22(2,3)41/h11-13,16,40-41H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26)/t11-,12-,13-,16+/m0/s1
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3.13E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma


J Med Chem 35: 3962-9 (1992)


Article DOI: 10.1021/jm00099a026
BindingDB Entry DOI: 10.7270/Q2028QG9
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010187
PNG
(CHEMBL320288 | [19-Acetylamino-4-carbamoyl-16-(3-g...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C23H38N10O10S2/c1-10(35)29-15-9-45-44-8-14(18(24)39)33-21(42)13(7-34)32-20(41)12(5-17(37)38)30-16(36)6-28-19(40)11(31-22(15)43)3-2-4-27-23(25)26/h11-15,34H,2-9H2,1H3,(H2,24,39)(H,28,40)(H,29,35)(H,30,36)(H,31,43)(H,32,41)(H,33,42)(H,37,38)(H4,25,26,27)/t11-,12-,13+,14+,15-/m1/s1
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5.30E+3n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010176
PNG
(CHEMBL107009 | [(4S,7R,13R,16S)-16-Acetylamino-4-c...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C20H33N9O8S2/c1-9(30)26-13-8-39-38-7-12(16(21)34)29-18(36)11(5-15(32)33)27-14(31)6-25-17(35)10(28-19(13)37)3-2-4-24-20(22)23/h10-13H,2-8H2,1H3,(H2,21,34)(H,25,35)(H,26,30)(H,27,31)(H,28,37)(H,29,36)(H,32,33)(H4,22,23,24)/t10-,11-,12-,13-/m1/s1
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n/an/a 1.62E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010193
PNG
(CHEMBL2370407 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES CN1[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC(C)(C)[C@@H](NC(C)=O)C1=O
Show InChI InChI=1S/C25H43N9O8S2/c1-12(35)31-18-22(42)34(6)14(8-7-9-29-23(27)28)21(41)30-11-15(36)32-13(10-16(37)38)20(40)33-17(19(26)39)24(2,3)43-44-25(18,4)5/h13-14,17-18H,7-11H2,1-6H3,(H2,26,39)(H,30,41)(H,31,35)(H,32,36)(H,33,40)(H,37,38)(H4,27,28,29)/t13-,14-,17-,18-/m0/s1
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n/an/a 370n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003323
PNG
(3-[2-(2-{2-[2-(2-Amino-acetylamino)-3-mercapto-3-m...)
Show SMILES C[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC(=O)CN)C(C)(C)S)C(O)=O
Show InChI InChI=1S/C35H59N13O14S2/c1-16(33(61)62)42-29(57)20(15-63)46-30(58)21-7-5-9-48(21)32(60)19(14-49)45-28(56)18(10-25(53)54)44-24(52)12-40-27(55)17(6-4-8-39-34(37)38)43-23(51)13-41-31(59)26(35(2,3)64)47-22(50)11-36/h16-21,26,49,63-64H,4-15,36H2,1-3H3,(H,40,55)(H,41,59)(H,42,57)(H,43,51)(H,44,52)(H,45,56)(H,46,58)(H,47,50)(H,53,54)(H,61,62)(H4,37,38,39)/t16-,17-,18-,19-,20-,21-,26+/m0/s1
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n/an/a 1.01E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomes


J Med Chem 35: 3962-9 (1992)


Article DOI: 10.1021/jm00099a026
BindingDB Entry DOI: 10.7270/Q2028QG9
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50003321
PNG
(3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...)
Show SMILES CC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(N)=O)C(C)(C)S
Show InChI InChI=1S/C22H39N9O8S2/c1-10(32)28-13(9-40)20(39)30-11(5-4-6-26-21(24)25)18(37)27-8-14(33)29-12(7-15(34)35)19(38)31-16(17(23)36)22(2,3)41/h11-13,16,40-41H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26)/t11-,12-,13-,16+/m0/s1
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n/an/a 2.03E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma


J Med Chem 35: 3962-9 (1992)


Article DOI: 10.1021/jm00099a026
BindingDB Entry DOI: 10.7270/Q2028QG9
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010162
PNG
(CHEMBL2370401 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES C[C@@H]1NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC1=O)C(N)=O)NC(C)=O
Show InChI InChI=1S/C23H39N9O8S2/c1-10-18(37)31-13(8-15(34)35)20(39)32-16(17(24)36)23(3,4)42-41-9-14(29-11(2)33)21(40)30-12(19(38)28-10)6-5-7-27-22(25)26/h10,12-14,16H,5-9H2,1-4H3,(H2,24,36)(H,28,38)(H,29,33)(H,30,40)(H,31,37)(H,32,39)(H,34,35)(H4,25,26,27)/t10-,12+,13+,14+,16-/m0/s1
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n/an/a 2.00E+5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010187
PNG
(CHEMBL320288 | [19-Acetylamino-4-carbamoyl-16-(3-g...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(N)=O
Show InChI InChI=1S/C23H38N10O10S2/c1-10(35)29-15-9-45-44-8-14(18(24)39)33-21(42)13(7-34)32-20(41)12(5-17(37)38)30-16(36)6-28-19(40)11(31-22(15)43)3-2-4-27-23(25)26/h11-15,34H,2-9H2,1H3,(H2,24,39)(H,28,40)(H,29,35)(H,30,36)(H,31,43)(H,32,41)(H,33,42)(H,37,38)(H4,25,26,27)/t11-,12-,13+,14+,15-/m1/s1
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n/an/a 3.27E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010177
PNG
(CHEMBL2370394 | [19-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC1=O)C(N)=O
Show InChI InChI=1S/C24H40N10O9S2/c1-11(35)31-14-10-44-45-24(2,3)18(19(25)40)34-22(43)13(7-17(38)39)33-16(37)9-29-20(41)12(5-4-6-28-23(26)27)32-15(36)8-30-21(14)42/h12-14,18H,4-10H2,1-3H3,(H2,25,40)(H,29,41)(H,30,42)(H,31,35)(H,32,36)(H,33,37)(H,34,43)(H,38,39)(H4,26,27,28)/t12-,13-,14+,18-/m0/s1
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n/an/a 1.14E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010161
PNG
(CHEMBL2370397 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES CN1[C@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C1=O
Show InChI InChI=1S/C23H39N9O8S2/c1-11(33)29-13-10-41-42-23(2,3)17(18(24)37)31-19(38)12(8-16(35)36)30-15(34)9-28-20(39)14(32(4)21(13)40)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,39)(H,29,33)(H,30,34)(H,31,38)(H,35,36)(H4,25,26,27)/t12-,13-,14-,17+/m1/s1
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n/an/a 355n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010171
PNG
(CHEMBL2370393 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Show SMILES CC(=O)N[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CSSC1(C)C)C(N)=O
Show InChI InChI=1S/C22H37N9O8S2/c1-10(32)28-16-20(39)30-11(5-4-6-26-21(24)25)18(37)27-8-14(33)29-12(7-15(34)35)19(38)31-13(17(23)36)9-40-41-22(16,2)3/h11-13,16H,4-9H2,1-3H3,(H2,23,36)(H,27,37)(H,28,32)(H,29,33)(H,30,39)(H,31,38)(H,34,35)(H4,24,25,26)/t11-,12-,13-,16-/m0/s1
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n/an/a 7.97E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010183
PNG
(CHEMBL353203 | [16-Acetylamino-4-carbamoyl-13-(3-g...)
Show SMILES CN1CC(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C(N)=O)C(C)(C)SSC[C@@H](NC(C)=O)C(=O)N[C@H](CCCN=C(N)N)C1=O
Show InChI InChI=1S/C23H39N9O8S2/c1-11(33)28-14-10-41-42-23(2,3)17(18(24)37)31-19(38)13(8-16(35)36)29-15(34)9-32(4)21(40)12(30-20(14)39)6-5-7-27-22(25)26/h12-14,17H,5-10H2,1-4H3,(H2,24,37)(H,28,33)(H,29,34)(H,30,39)(H,31,38)(H,35,36)(H4,25,26,27)/t12-,13-,14-,17+/m1/s1
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n/an/a 7.34E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010175
PNG
(CHEMBL107169 | [19-Acetylamino-4-carbamoyl-13-(3-g...)
Show SMILES CC(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC1=O)C(N)=O
Show InChI InChI=1S/C22H36N10O9S2/c1-10(33)29-14-9-43-42-8-13(18(23)38)32-21(41)12(5-17(36)37)31-16(35)7-27-19(39)11(3-2-4-26-22(24)25)30-15(34)6-28-20(14)40/h11-14H,2-9H2,1H3,(H2,23,38)(H,27,39)(H,28,40)(H,29,33)(H,30,34)(H,31,35)(H,32,41)(H,36,37)(H4,24,25,26)/t11-,12-,13-,14+/m0/s1
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n/an/a 5.20E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of canine platelet-rich plasma agregation induced by ADP


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair
Integrin alpha-IIb/beta-3


(Homo sapiens (Human))
BDBM50010166
PNG
(CHEMBL2370399 | [16-Acetylamino-13-(4-amino-butyl)...)
Show SMILES CC(=O)N[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](CCCCN)NC1=O)C(N)=O
Show InChI InChI=1S/C22H37N7O8S2/c1-11(30)26-14-10-38-39-22(2,3)17(18(24)34)29-20(36)13(8-16(32)33)27-15(31)9-25-19(35)12(28-21(14)37)6-4-5-7-23/h12-14,17H,4-10,23H2,1-3H3,(H2,24,34)(H,25,35)(H,26,30)(H,27,31)(H,28,37)(H,29,36)(H,32,33)/t12-,13-,14-,17+/m1/s1
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n/an/a 5.53E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL


Assay Description
Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptor


J Med Chem 34: 3114-25 (1991)


Article DOI: 10.1021/jm00114a022
BindingDB Entry DOI: 10.7270/Q2445KF0
More data for this
Ligand-Target Pair