BindingDB logo
myBDB logout

1 similar compounds to monomer 16415

Compile data set for download or QSAR
Wt: 297.2
BDBM50005526

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005526   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50005526
PNG
((5-Acetyl-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-y...)
Show SMILES CC(=O)c1cc2C(=O)N(CC(O)=O)C(=O)c3cccc(c1)c23
Show InChI InChI=1S/C16H11NO5/c1-8(18)10-5-9-3-2-4-11-14(9)12(6-10)16(22)17(15(11)21)7-13(19)20/h2-6H,7H2,1H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 640n/an/an/an/an/an/a



Ohio State University

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Rat Lens Aldose reductase (RLAR)


J Med Chem 35: 1117-20 (1992)


Article DOI: 10.1021/jm00084a017
BindingDB Entry DOI: 10.7270/Q2D21WKS
More data for this
Ligand-Target Pair
Aldose reductase


(Rattus norvegicus)
BDBM50005526
PNG
((5-Acetyl-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-y...)
Show SMILES CC(=O)c1cc2C(=O)N(CC(O)=O)C(=O)c3cccc(c1)c23
Show InChI InChI=1S/C16H11NO5/c1-8(18)10-5-9-3-2-4-11-14(9)12(6-10)16(22)17(15(11)21)7-13(19)20/h2-6H,7H2,1H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.40E+3n/an/an/an/an/an/a



Ohio State University

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Rat kidney Aldehyde reductase (RKALR)


J Med Chem 35: 1117-20 (1992)


Article DOI: 10.1021/jm00084a017
BindingDB Entry DOI: 10.7270/Q2D21WKS
More data for this
Ligand-Target Pair