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3 similar compounds to monomer 50006957

Compile data set for download or QSAR
Wt: 272.3
BDBM50006961
Wt: 300.3
BDBM50006960
Wt: 286.3
BDBM50006965

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50006961,50006960,50006965   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006960
PNG
(2-(2-Diethylamino-ethyl)-4,9-dihydro-2,4,9-triaza-...)
Show SMILES CCN(CC)CCn1c(=O)[nH]c2c3ccccc3[nH]c2c1=O
Show InChI InChI=1S/C16H20N4O2/c1-3-19(4-2)9-10-20-15(21)14-13(18-16(20)22)11-7-5-6-8-12(11)17-14/h5-8,17H,3-4,9-10H2,1-2H3,(H,18,22)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006965
PNG
(2-(3-Dimethylamino-propyl)-4,9-dihydro-2,4,9-triaz...)
Show SMILES CN(C)CCCn1c(=O)[nH]c2c3ccccc3[nH]c2c1=O
Show InChI InChI=1S/C15H18N4O2/c1-18(2)8-5-9-19-14(20)13-12(17-15(19)21)10-6-3-4-7-11(10)16-13/h3-4,6-7,16H,5,8-9H2,1-2H3,(H,17,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006961
PNG
(2-(2-Dimethylamino-ethyl)-4,9-dihydro-2,4,9-triaza...)
Show SMILES CN(C)CCn1c(=O)[nH]c2c3ccccc3[nH]c2c1=O
Show InChI InChI=1S/C14H16N4O2/c1-17(2)7-8-18-13(19)12-11(16-14(18)20)9-5-3-4-6-10(9)15-12/h3-6,15H,7-8H2,1-2H3,(H,16,20)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair