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10 molecules are shown

Wt: 389.4
BDBM50282717
Wt: 262.3
BDBM50008430
Wt: 264.3
BDBM50008431
Wt: 324.4
BDBM50022751
Wt: 264.3
BDBM50027043
Wt: 308.3
BDBM50046325
Purchase
Wt: 293.2
BDBM50105264
Wt: 418.5
BDBM50282714
Wt: 321.4
BDBM50282724
Wt: 274.3
BDBM50027041

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 49 hits for monomerid = 50282717,50008430,50008431,50022751,50027043,50046325,50105264,50282714,50282724,50027041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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1.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
50% inhibitory activity against enkephalinase purified from rat kidney with [3H]D-Ala2-Leu-enkephalin (20 nM) as substrate.


J Med Chem 28: 1158-69 (1985)


Article DOI: 10.1021/jm00147a007
BindingDB Entry DOI: 10.7270/Q20C4WB5
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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1.70n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)


J Med Chem 44: 3523-30 (2001)


Article DOI: 10.1021/jm0102248
BindingDB Entry DOI: 10.7270/Q2QN67HK
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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3.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate


J Med Chem 28: 1158-69 (1985)


Article DOI: 10.1021/jm00147a007
BindingDB Entry DOI: 10.7270/Q20C4WB5
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
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4.60n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
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6.40n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against LTA 4 hydrolase in aminopeptidase assay


Bioorg Med Chem Lett 5: 2517-2522 (1995)


Article DOI: 10.1016/0960-894X(95)00441-U
BindingDB Entry DOI: 10.7270/Q2959J1M
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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18n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against LTA 4 hydrolase in epoxide hydrolase assay


Bioorg Med Chem Lett 5: 2517-2522 (1995)


Article DOI: 10.1016/0960-894X(95)00441-U
BindingDB Entry DOI: 10.7270/Q2959J1M
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Leucine aminopeptidase


(Homo sapiens)
BDBM50027041
PNG
(2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-4-met...)
Show SMILES CC(C)C[C@@H](N)[C@H](O)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C13H26N2O4/c1-7(2)5-9(14)11(16)12(17)15-10(13(18)19)6-8(3)4/h7-11,16H,5-6,14H2,1-4H3,(H,15,17)(H,18,19)
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120n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50027043
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@H](O)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m0/s1
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500n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Leucine aminopeptidase from porcine kidney and the inhibition constant was determined after preincubatin...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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510n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aspartyl aminopeptidase


(Homo sapiens)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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510n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards cytosolic aminopeptidase


J Med Chem 35: 451-6 (1992)


Article DOI: 10.1021/jm00081a005
BindingDB Entry DOI: 10.7270/Q2CR5SBH
More data for this
Ligand-Target Pair
Aminopeptidase


(Homo sapiens)
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
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550n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aspartyl aminopeptidase


(Homo sapiens)
BDBM50008430
PNG
(3-Amino-N-(3-methyl-butyl)-2-oxo-4-phenyl-butyrami...)
Show SMILES CC(C)CCNC(=O)C(=O)C(N)Cc1ccccc1
Show InChI InChI=1S/C15H22N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13H,8-10,16H2,1-2H3,(H,17,19)
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1.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards cytosolic aminopeptidase


J Med Chem 35: 451-6 (1992)


Article DOI: 10.1021/jm00081a005
BindingDB Entry DOI: 10.7270/Q2CR5SBH
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
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1.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008430
PNG
(3-Amino-N-(3-methyl-butyl)-2-oxo-4-phenyl-butyrami...)
Show SMILES CC(C)CCNC(=O)C(=O)C(N)Cc1ccccc1
Show InChI InChI=1S/C15H22N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13H,8-10,16H2,1-2H3,(H,17,19)
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1.50E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


J Med Chem 35: 451-6 (1992)


Article DOI: 10.1021/jm00081a005
BindingDB Entry DOI: 10.7270/Q2CR5SBH
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50008430
PNG
(3-Amino-N-(3-methyl-butyl)-2-oxo-4-phenyl-butyrami...)
Show SMILES CC(C)CCNC(=O)C(=O)C(N)Cc1ccccc1
Show InChI InChI=1S/C15H22N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13H,8-10,16H2,1-2H3,(H,17,19)
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2.50E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards microsomal aminopeptidase


J Med Chem 35: 451-6 (1992)


Article DOI: 10.1021/jm00081a005
BindingDB Entry DOI: 10.7270/Q2CR5SBH
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
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4.40E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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7.00E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Compound was evaluated for inhibition of enkephalin degrading enzyme, aminopeptidase N(APN)


J Med Chem 44: 3523-30 (2001)


Article DOI: 10.1021/jm0102248
BindingDB Entry DOI: 10.7270/Q2QN67HK
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
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9.10E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50027041
PNG
(2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-4-met...)
Show SMILES CC(C)C[C@@H](N)[C@H](O)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C13H26N2O4/c1-7(2)5-9(14)11(16)12(17)15-10(13(18)19)6-8(3)4/h7-11,16H,5-6,14H2,1-4H3,(H,15,17)(H,18,19)
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1.18E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50027043
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@H](O)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m0/s1
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1.60E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) from porcine kidney and the inhibition constant was determined after preincubati...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50027043
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@H](O)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m0/s1
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1.60E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50027043
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@H](O)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m0/s1
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1.63E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50046325
PNG
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13-,14-/m0/s1
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1.70E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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2.00E+4n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards microsomal aminopeptidase


J Med Chem 35: 451-6 (1992)


Article DOI: 10.1021/jm00081a005
BindingDB Entry DOI: 10.7270/Q2CR5SBH
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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2.00E+4n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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3.90E+4n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


J Med Chem 35: 451-6 (1992)


Article DOI: 10.1021/jm00081a005
BindingDB Entry DOI: 10.7270/Q2CR5SBH
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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3.90E+4n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50046325
PNG
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13-,14-/m0/s1
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2.00E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50046325
PNG
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13-,14-/m0/s1
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5.00E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1


J Med Chem 27: 417-22 (1984)


Article DOI: 10.1021/jm00370a001
BindingDB Entry DOI: 10.7270/Q280535G
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aminopeptidase B


(Mus musculus)
BDBM50282717
PNG
(1-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-m...)
Show SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C21H31N3O4/c1-14(2)12-17(20(26)24-11-7-10-18(24)21(27)28-3)23-19(25)16(22)13-15-8-5-4-6-9-15/h4-6,8-9,14,16-18H,7,10-13,22H2,1-3H3,(H,23,25)/t16-,17-,18-/m0/s1
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n/an/a 8.24E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Aminopeptidase B in murine L-cells by Aoyagi method.


Bioorg Med Chem Lett 4: 1491-1496 (1994)


Article DOI: 10.1016/S0960-894X(01)80519-9
BindingDB Entry DOI: 10.7270/Q26M37B6
More data for this
Ligand-Target Pair
Aminopeptidase B


(Mus musculus)
BDBM50282714
PNG
(1-[(S)-2-((1R,2S)-2-Amino-1-carbamoyl-3-phenyl-pro...)
Show SMILES COC(=O)C1CCCN1C(=O)[C@H](CC(C)C)N[C@@H]([C@@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C22H34N4O4/c1-14(2)12-17(21(28)26-11-7-10-18(26)22(29)30-3)25-19(20(24)27)16(23)13-15-8-5-4-6-9-15/h4-6,8-9,14,16-19,25H,7,10-13,23H2,1-3H3,(H2,24,27)/t16-,17-,18?,19-/m0/s1
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n/an/a 1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Aminopeptidase B in murine L-cells by Aoyagi method.


Bioorg Med Chem Lett 4: 1491-1496 (1994)


Article DOI: 10.1016/S0960-894X(01)80519-9
BindingDB Entry DOI: 10.7270/Q26M37B6
More data for this
Ligand-Target Pair
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human Leukotriene A4 hydrolase


Bioorg Med Chem Lett 5: 2517-2522 (1995)


Article DOI: 10.1016/0960-894X(95)00441-U
BindingDB Entry DOI: 10.7270/Q2959J1M
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aminopeptidase B


(Rattus norvegicus)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
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n/an/a 6.40E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetry


J Med Chem 20: 510-5 (1977)


Article DOI: 10.1021/jm00214a010
BindingDB Entry DOI: 10.7270/Q29W0H11
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50046325
PNG
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13-,14-/m0/s1
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n/an/a 4.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetry


J Med Chem 20: 510-5 (1977)


Article DOI: 10.1021/jm00214a010
BindingDB Entry DOI: 10.7270/Q29W0H11
More data for this
Ligand-Target Pair
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM50046325
PNG
((S)-2-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyryla...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13-,14-/m0/s1
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n/an/a 2.00E+4n/an/an/an/an/an/a



Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes


J Med Chem 36: 211-20 (1993)


Article DOI: 10.1021/jm00054a004
BindingDB Entry DOI: 10.7270/Q2T152P3
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 46n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against rabbit kidney neutral endopeptidase (NEP)


Bioorg Med Chem Lett 5: 2517-2522 (1995)


Article DOI: 10.1016/0960-894X(95)00441-U
BindingDB Entry DOI: 10.7270/Q2959J1M
More data for this
Ligand-Target Pair
Thermolysin


(Bacillus thermoproteolyticus)
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)


J Med Chem 38: 2119-29 (1995)


Article DOI: 10.1021/jm00012a011
BindingDB Entry DOI: 10.7270/Q2D79C2M
More data for this
Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1)


(Homo sapiens (Human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 8n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1


J Med Chem 38: 2119-29 (1995)


Article DOI: 10.1021/jm00012a011
BindingDB Entry DOI: 10.7270/Q2D79C2M
More data for this
Ligand-Target Pair
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 5n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against Leukotriene A4 hydrolase


J Med Chem 43: 721-35 (2000)


Article DOI: 10.1021/jm990496z
BindingDB Entry DOI: 10.7270/Q2CN74MZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity was determined for LTB4 production in human whole blood.


J Med Chem 43: 721-35 (2000)


Article DOI: 10.1021/jm990496z
BindingDB Entry DOI: 10.7270/Q2CN74MZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against rabbit lung angiotensin-converting enzyme (ACE)


Bioorg Med Chem Lett 5: 2517-2522 (1995)


Article DOI: 10.1016/0960-894X(95)00441-U
BindingDB Entry DOI: 10.7270/Q2959J1M
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 8n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against big ET-1 of Neutral endopeptidase


J Med Chem 38: 2119-29 (1995)


Article DOI: 10.1021/jm00012a011
BindingDB Entry DOI: 10.7270/Q2D79C2M
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 1n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against Leu-enkeph of Neutral endopeptidase


J Med Chem 38: 2119-29 (1995)


Article DOI: 10.1021/jm00012a011
BindingDB Entry DOI: 10.7270/Q2D79C2M
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50105264
PNG
(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C([O-])=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/p-1/t9-,11+/m0/s1
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n/an/a 1.70n/an/an/an/an/an/a



UA 498 CNRS

Curated by ChEMBL


Assay Description
Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)


J Med Chem 31: 1825-31 (1988)


Article DOI: 10.1021/jm00117a025
BindingDB Entry DOI: 10.7270/Q2R49RC8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50282724
PNG
((S)-2-((1R,2S)-2-Amino-1-carbamoyl-3-phenyl-propyl...)
Show SMILES COC(=O)[C@H](CC(C)C)N[C@@H]([C@@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C17H27N3O3/c1-11(2)9-14(17(22)23-3)20-15(16(19)21)13(18)10-12-7-5-4-6-8-12/h4-8,11,13-15,20H,9-10,18H2,1-3H3,(H2,19,21)/t13-,14-,15-/m0/s1
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n/an/a 1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Aminopeptidase M.


Bioorg Med Chem Lett 4: 1491-1496 (1994)


Article DOI: 10.1016/S0960-894X(01)80519-9
BindingDB Entry DOI: 10.7270/Q26M37B6
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Aminopeptidase N


(Homo sapiens)
BDBM50282717
PNG
(1-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-m...)
Show SMILES COC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C21H31N3O4/c1-14(2)12-17(20(26)24-11-7-10-18(24)21(27)28-3)23-19(25)16(22)13-15-8-5-4-6-9-15/h4-6,8-9,14,16-18H,7,10-13,22H2,1-3H3,(H,23,25)/t16-,17-,18-/m0/s1
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n/an/a 7.93E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Aminopeptidase M.


Bioorg Med Chem Lett 4: 1491-1496 (1994)


Article DOI: 10.1016/S0960-894X(01)80519-9
BindingDB Entry DOI: 10.7270/Q26M37B6
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Aminopeptidase N


(Homo sapiens)
BDBM50282714
PNG
(1-[(S)-2-((1R,2S)-2-Amino-1-carbamoyl-3-phenyl-pro...)
Show SMILES COC(=O)C1CCCN1C(=O)[C@H](CC(C)C)N[C@@H]([C@@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C22H34N4O4/c1-14(2)12-17(21(28)26-11-7-10-18(26)22(29)30-3)25-19(20(24)27)16(23)13-15-8-5-4-6-9-15/h4-6,8-9,14,16-19,25H,7,10-13,23H2,1-3H3,(H2,24,27)/t16-,17-,18?,19-/m0/s1
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n/an/a 1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Aminopeptidase M.


Bioorg Med Chem Lett 4: 1491-1496 (1994)


Article DOI: 10.1016/S0960-894X(01)80519-9
BindingDB Entry DOI: 10.7270/Q26M37B6
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Aminopeptidase B


(Mus musculus)
BDBM50282724
PNG
((S)-2-((1R,2S)-2-Amino-1-carbamoyl-3-phenyl-propyl...)
Show SMILES COC(=O)[C@H](CC(C)C)N[C@@H]([C@@H](N)Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C17H27N3O3/c1-11(2)9-14(17(22)23-3)20-15(16(19)21)13(18)10-12-7-5-4-6-8-12/h4-8,11,13-15,20H,9-10,18H2,1-3H3,(H2,19,21)/t13-,14-,15-/m0/s1
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n/an/a 1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Aminopeptidase B in murine L-cells by Aoyagi method.


Bioorg Med Chem Lett 4: 1491-1496 (1994)


Article DOI: 10.1016/S0960-894X(01)80519-9
BindingDB Entry DOI: 10.7270/Q26M37B6
More data for this
Ligand-Target Pair