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3 similar compounds to monomer 50010152

Compile data set for download or QSAR
Wt: 390.9
BDBM50010147
Wt: 390.9
BDBM50010151
Wt: 376.8
BDBM50010154

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010147,50010151,50010154   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT1B


(RAT)
BDBM50010147
PNG
(6-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylm...)
Show SMILES CCCCc1nc(CO)c(Cl)n1Cc1ccc2CC(C)(CCc2c1)C(O)=O
Show InChI InChI=1/C21H27ClN2O3/c1-3-4-5-18-23-17(13-25)19(22)24(18)12-14-6-7-16-11-21(2,20(26)27)9-8-15(16)10-14/h6-7,10,25H,3-5,8-9,11-13H2,1-2H3,(H,26,27)
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Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair
Angiotensin II AT1B


(RAT)
BDBM50010154
PNG
(6-(2-Butyl-5-chloro-4-hydroxymethyl-imidazol-1-ylm...)
Show SMILES CCCCc1nc(CO)c(Cl)n1Cc1ccc2CC(CCc2c1)C(O)=O
Show InChI InChI=1/C20H25ClN2O3/c1-2-3-4-18-22-17(12-24)19(21)23(18)11-13-5-6-15-10-16(20(25)26)8-7-14(15)9-13/h5-6,9,16,24H,2-4,7-8,10-12H2,1H3,(H,25,26)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair
Angiotensin II AT1B


(RAT)
BDBM50010151
PNG
(6-(2-Butyl-4-chloro-5-hydroxymethyl-imidazol-1-ylm...)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc2CC(C)(CCc2c1)C(O)=O
Show InChI InChI=1/C21H27ClN2O3/c1-3-4-5-18-23-19(22)17(13-25)24(18)12-14-6-7-16-11-21(2,20(26)27)9-8-15(16)10-14/h6-7,10,25H,3-5,8-9,11-13H2,1-2H3,(H,26,27)
PDB

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PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair