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1 similar compounds to monomer 50014933

Wt: 357.3
BDBM50014937

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014937   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arylamine N-acetyltransferase 2


(Mus musculus)
BDBM50014937
PNG
(CHEMBL3262076)
Show SMILES O=C(Cc1ccccc1)NC1=C(c2ccoc2)C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C22H15NO4/c24-18(12-14-6-2-1-3-7-14)23-20-19(15-10-11-27-13-15)21(25)16-8-4-5-9-17(16)22(20)26/h1-11,13H,12H2,(H,23,24)
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UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.35E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged mouse NAT2 expressed in Escherichia coli Rosetta(DE3)pLysS cells assessed as rate of free thiol coen...


Bioorg Med Chem 22: 3030-54 (2014)


Article DOI: 10.1016/j.bmc.2014.03.015
BindingDB Entry DOI: 10.7270/Q2S75HVG
More data for this
Ligand-Target Pair
Arylamine N-acetyltransferase 1


(Homo sapiens)
BDBM50014937
PNG
(CHEMBL3262076)
Show SMILES O=C(Cc1ccccc1)NC1=C(c2ccoc2)C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C22H15NO4/c24-18(12-14-6-2-1-3-7-14)23-20-19(15-10-11-27-13-15)21(25)16-8-4-5-9-17(16)22(20)26/h1-11,13H,12H2,(H,23,24)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.93E+4n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's method


Bioorg Med Chem 22: 3030-54 (2014)


Article DOI: 10.1016/j.bmc.2014.03.015
BindingDB Entry DOI: 10.7270/Q2S75HVG
More data for this
Ligand-Target Pair