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26 similar compounds to monomer 50000091

Compile data set for download or QSAR
Wt: 299.4
BDBM50017232
Wt: 299.4
BDBM50021328
Wt: 299.4
BDBM50045114
Wt: 315.4
BDBM50083924
Wt: 285.3
BDBM50123985
Wt: 271.3
BDBM50138012
Wt: 303.3
BDBM50138015
Wt: 271.3
BDBM50137988
Wt: 341.4
BDBM50137989
Wt: 325.4
BDBM50137990
Wt: 333.4
BDBM50137991
Wt: 315.4
BDBM50137992
Wt: 393.5
BDBM50137995
Wt: 325.4
BDBM50138002
Wt: 295.3
BDBM50138003
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 50017232,50021328,50045114,50083924,50123985,50138012,50138015,50137988,50137989,50137990,50137991,50137992,50137995,50138002,50138003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50137989
PNG
(3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmo...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1
Show InChI InChI=1S/C21H27NO3/c23-14-6-7-16-18(12-14)21-8-2-1-5-17(21)19(20(16)24)22(10-9-21)13-15-4-3-11-25-15/h6-7,12,15,17,19,23H,1-5,8-11,13H2/t15-,17-,19-,21+/m0/s1
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0.180n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50137989
PNG
(3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmo...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1
Show InChI InChI=1S/C21H27NO3/c23-14-6-7-16-18(12-14)21-8-2-1-5-17(21)19(20(16)24)22(10-9-21)13-15-4-3-11-25-15/h6-7,12,15,17,19,23H,1-5,8-11,13H2/t15-,17-,19-,21+/m0/s1
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0.380n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50137990
PNG
(3-Hydroxy-10-keto-N-cyclobutylmethylmorphinan | CH...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1
Show InChI InChI=1S/C21H27NO2/c23-15-7-8-16-18(12-15)21-9-2-1-6-17(21)19(20(16)24)22(11-10-21)13-14-4-3-5-14/h7-8,12,14,17,19,23H,1-6,9-11,13H2/t17-,19-,21+/m0/s1
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0.480n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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0.620n/an/an/an/an/an/an/an/a



Rensselaer Polytechnic Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brain


Bioorg Med Chem Lett 19: 203-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.134
BindingDB Entry DOI: 10.7270/Q2RX9D1K
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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0.780n/an/an/an/an/an/an/an/a



Rensselaer Polytechnic Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brain


Bioorg Med Chem Lett 19: 203-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.134
BindingDB Entry DOI: 10.7270/Q2RX9D1K
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50123985
PNG
(3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,...)
Show SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16?,18-/m0/s1
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1n/an/an/an/an/an/an/an/a



Rensselaer Polytechnic Institute

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U69,593 as radioligand


J Med Chem 46: 838-49 (2003)


Article DOI: 10.1021/jm020429w
BindingDB Entry DOI: 10.7270/Q2Z31Z09
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50137989
PNG
(3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmo...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1
Show InChI InChI=1S/C21H27NO3/c23-14-6-7-16-18(12-14)21-8-2-1-5-17(21)19(20(16)24)22(10-9-21)13-15-4-3-11-25-15/h6-7,12,15,17,19,23H,1-5,8-11,13H2/t15-,17-,19-,21+/m0/s1
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1n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(MOUSE)
BDBM50017232
PNG
(3-Cyclopropylmethyl-5-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC1CN(CC2CC2)C2C(C)C1c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-13-10-20(9-12-4-5-12)18-11(2)17(13)16-8-14(21)6-7-15(16)19(18)22/h6-8,11-13,17-18,21H,3-5,9-10H2,1-2H3
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1.30n/an/an/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
Binding affinity for mouse opioid receptor mu


J Med Chem 32: 2221-6 (1989)


Article DOI: 10.1021/jm00129a031
BindingDB Entry DOI: 10.7270/Q2Q240T3
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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1.93n/an/an/an/an/an/an/an/a



University of Michigan

Curated by PDSP Ki Database




J Chem Neuroanat 25: 233-47 (2003)


BindingDB Entry DOI: 10.7270/Q2XP73G2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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2.12n/an/an/an/an/an/an/an/a



University of Michigan

Curated by PDSP Ki Database




J Chem Neuroanat 25: 233-47 (2003)


BindingDB Entry DOI: 10.7270/Q2XP73G2
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Mus musculus (Mouse))
BDBM50017232
PNG
(3-Cyclopropylmethyl-5-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC1CN(CC2CC2)C2C(C)C1c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-13-10-20(9-12-4-5-12)18-11(2)17(13)16-8-14(21)6-7-15(16)19(18)22/h6-8,11-13,17-18,21H,3-5,9-10H2,1-2H3
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2.30n/an/an/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
Binding affinity for mouse sigma opioid receptor


J Med Chem 32: 2221-6 (1989)


Article DOI: 10.1021/jm00129a031
BindingDB Entry DOI: 10.7270/Q2Q240T3
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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2.46n/an/an/an/an/an/an/an/a



University of Michigan

Curated by PDSP Ki Database




J Chem Neuroanat 25: 233-47 (2003)


BindingDB Entry DOI: 10.7270/Q2XP73G2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50137990
PNG
(3-Hydroxy-10-keto-N-cyclobutylmethylmorphinan | CH...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1
Show InChI InChI=1S/C21H27NO2/c23-15-7-8-16-18(12-15)21-9-2-1-6-17(21)19(20(16)24)22(11-10-21)13-14-4-3-5-14/h7-8,12,14,17,19,23H,1-6,9-11,13H2/t17-,19-,21+/m0/s1
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3.30n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50123985
PNG
(3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,...)
Show SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16?,18-/m0/s1
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3.30n/an/an/an/an/an/an/an/a



Rensselaer Polytechnic Institute

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligand


J Med Chem 46: 838-49 (2003)


Article DOI: 10.1021/jm020429w
BindingDB Entry DOI: 10.7270/Q2Z31Z09
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Mus musculus (Mouse))
BDBM50017232
PNG
(3-Cyclopropylmethyl-5-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC1CN(CC2CC2)C2C(C)C1c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-13-10-20(9-12-4-5-12)18-11(2)17(13)16-8-14(21)6-7-15(16)19(18)22/h6-8,11-13,17-18,21H,3-5,9-10H2,1-2H3
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6n/an/an/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
Binding affinity for mouse opioid receptor kappa


J Med Chem 32: 2221-6 (1989)


Article DOI: 10.1021/jm00129a031
BindingDB Entry DOI: 10.7270/Q2Q240T3
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50138002
PNG
(3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan |...)
Show SMILES CC(C)=CCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C21H27NO2/c1-14(2)8-11-22-12-10-21-9-4-3-5-17(21)19(22)20(24)16-7-6-15(23)13-18(16)21/h6-8,13,17,19,23H,3-5,9-12H2,1-2H3/t17-,19-,21+/m0/s1
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7.40n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50138012
PNG
(3-Methoxy normorphinan | CHEMBL297467)
Show SMILES COc1ccc2C(=O)[C@H]3NCC[C@@]4(CCCC[C@@H]34)c2c1
Show InChI InChI=1S/C17H21NO2/c1-20-11-5-6-12-14(10-11)17-7-3-2-4-13(17)15(16(12)19)18-9-8-17/h5-6,10,13,15,18H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1
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16n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50137992
PNG
(3-Hydroxy-10-keto-N-(2-methoxyethyl)morphinan | CH...)
Show SMILES COCCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C19H25NO3/c1-23-11-10-20-9-8-19-7-3-2-4-15(19)17(20)18(22)14-6-5-13(21)12-16(14)19/h5-6,12,15,17,21H,2-4,7-11H2,1H3/t15-,17-,19+/m0/s1
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17n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50138002
PNG
(3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan |...)
Show SMILES CC(C)=CCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C21H27NO2/c1-14(2)8-11-22-12-10-21-9-4-3-5-17(21)19(22)20(24)16-7-6-15(23)13-18(16)21/h6-8,13,17,19,23H,3-5,9-12H2,1-2H3/t17-,19-,21+/m0/s1
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19n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50123985
PNG
(3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,...)
Show SMILES C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16?,18-/m0/s1
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20n/an/an/an/an/an/an/an/a



Rensselaer Polytechnic Institute

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligand


J Med Chem 46: 838-49 (2003)


Article DOI: 10.1021/jm020429w
BindingDB Entry DOI: 10.7270/Q2Z31Z09
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50137988
PNG
(3-Hydroxy-10-keto-N-methylmorphinan | CHEMBL432120)
Show SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C17H21NO2/c1-18-9-8-17-7-3-2-4-13(17)15(18)16(20)12-6-5-11(19)10-14(12)17/h5-6,10,13,15,19H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1
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21n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50137988
PNG
(3-Hydroxy-10-keto-N-methylmorphinan | CHEMBL432120)
Show SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C17H21NO2/c1-18-9-8-17-7-3-2-4-13(17)15(18)16(20)12-6-5-11(19)10-14(12)17/h5-6,10,13,15,19H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1
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47n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50138003
PNG
(3-Hydroxy-10-keto-N-propargylmorphinan | CHEMBL298...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC#C)c2c1
Show InChI InChI=1S/C19H21NO2/c1-2-10-20-11-9-19-8-4-3-5-15(19)17(20)18(22)14-7-6-13(21)12-16(14)19/h1,6-7,12,15,17,21H,3-5,8-11H2/t15-,17-,19+/m0/s1
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60n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50137992
PNG
(3-Hydroxy-10-keto-N-(2-methoxyethyl)morphinan | CH...)
Show SMILES COCCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C19H25NO3/c1-23-11-10-20-9-8-19-7-3-2-4-15(19)17(20)18(22)14-6-5-13(21)12-16(14)19/h5-6,12,15,17,21H,2-4,7-11H2,1H3/t15-,17-,19+/m0/s1
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90n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50138012
PNG
(3-Methoxy normorphinan | CHEMBL297467)
Show SMILES COc1ccc2C(=O)[C@H]3NCC[C@@]4(CCCC[C@@H]34)c2c1
Show InChI InChI=1S/C17H21NO2/c1-20-11-5-6-12-14(10-11)17-7-3-2-4-13(17)15(16(12)19)18-9-8-17/h5-6,10,13,15,18H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1
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110n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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188n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Binding affinity for kappa opioid receptor was evaluated by displacing [3H]- diprenorphine


J Med Chem 36: 1860-5 (1993)


Article DOI: 10.1021/jm00065a009
BindingDB Entry DOI: 10.7270/Q2SF2WTH
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50138003
PNG
(3-Hydroxy-10-keto-N-propargylmorphinan | CHEMBL298...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC#C)c2c1
Show InChI InChI=1S/C19H21NO2/c1-2-10-20-11-9-19-8-4-3-5-15(19)17(20)18(22)14-7-6-13(21)12-16(14)19/h1,6-7,12,15,17,21H,3-5,8-11H2/t15-,17-,19+/m0/s1
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190n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50138015
PNG
(3-Hydroxy-10-keto-N-(2-fluoroethyl)morphinan | CHE...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCF)c2c1
Show InChI InChI=1S/C18H22FNO2/c19-8-10-20-9-7-18-6-2-1-3-14(18)16(20)17(22)13-5-4-12(21)11-15(13)18/h4-5,11,14,16,21H,1-3,6-10H2/t14-,16-,18+/m0/s1
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250n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50137990
PNG
(3-Hydroxy-10-keto-N-cyclobutylmethylmorphinan | CH...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1
Show InChI InChI=1S/C21H27NO2/c23-15-7-8-16-18(12-15)21-9-2-1-6-17(21)19(20(16)24)22(11-10-21)13-14-4-3-5-14/h7-8,12,14,17,19,23H,1-6,9-11,13H2/t17-,19-,21+/m0/s1
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260n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50137995
PNG
(3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmor...)
Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12
Show InChI InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1
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290n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50138012
PNG
(3-Methoxy normorphinan | CHEMBL297467)
Show SMILES COc1ccc2C(=O)[C@H]3NCC[C@@]4(CCCC[C@@H]34)c2c1
Show InChI InChI=1S/C17H21NO2/c1-20-11-5-6-12-14(10-11)17-7-3-2-4-13(17)15(16(12)19)18-9-8-17/h5-6,10,13,15,18H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1
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390n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50137991
PNG
(3-O-Propargyl-10-keto-N-propargylmorphinan | CHEMB...)
Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC#C)c2cc(OCC#C)ccc12
Show InChI InChI=1S/C22H23NO2/c1-3-12-23-13-11-22-10-6-5-7-18(22)20(23)21(24)17-9-8-16(15-19(17)22)25-14-4-2/h1-2,8-9,15,18,20H,5-7,10-14H2/t18-,20-,22+/m0/s1
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500n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50138015
PNG
(3-Hydroxy-10-keto-N-(2-fluoroethyl)morphinan | CHE...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCF)c2c1
Show InChI InChI=1S/C18H22FNO2/c19-8-10-20-9-7-18-6-2-1-3-14(18)16(20)17(22)13-5-4-12(21)11-15(13)18/h4-5,11,14,16,21H,1-3,6-10H2/t14-,16-,18+/m0/s1
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560n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50045114
PNG
(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Show SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21
Show InChI InChI=1/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3
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690n/an/an/an/an/an/an/an/a



Universit£ di Catania

Curated by ChEMBL


Assay Description
Binding affinity for mu opioid receptor was evaluated by displacing [3H]- diprenorphine


J Med Chem 36: 1860-5 (1993)


Article DOI: 10.1021/jm00065a009
BindingDB Entry DOI: 10.7270/Q2SF2WTH
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50137991
PNG
(3-O-Propargyl-10-keto-N-propargylmorphinan | CHEMB...)
Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC#C)c2cc(OCC#C)ccc12
Show InChI InChI=1S/C22H23NO2/c1-3-12-23-13-11-22-10-6-5-7-18(22)20(23)21(24)17-9-8-16(15-19(17)22)25-14-4-2/h1-2,8-9,15,18,20H,5-7,10-14H2/t18-,20-,22+/m0/s1
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710n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50083924
PNG
(8-Hydroxy-6,11-dimethyl-3-(tetrahydro-furan-2-ylme...)
Show SMILES C[C@H]1C2N(CC3CCCO3)CC[C@]1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1S/C19H25NO3/c1-12-17-18(22)15-6-5-13(21)10-16(15)19(12,2)7-8-20(17)11-14-4-3-9-23-14/h5-6,10,12,14,17,21H,3-4,7-9,11H2,1-2H3/t12-,14?,17?,19-/m0/s1
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720n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor kappa 1 by displacing the radioligand [3H]U-69593 from guinea pig brain membrane


J Med Chem 43: 114-22 (2000)


Article DOI: 10.1021/jm9903343
BindingDB Entry DOI: 10.7270/Q20V8DGH
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50137995
PNG
(3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmor...)
Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12
Show InChI InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1
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800n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50138002
PNG
(3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan |...)
Show SMILES CC(C)=CCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C21H27NO2/c1-14(2)8-11-22-12-10-21-9-4-3-5-17(21)19(22)20(24)16-7-6-15(23)13-18(16)21/h6-8,13,17,19,23H,3-5,9-12H2,1-2H3/t17-,19-,21+/m0/s1
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1.10E+3n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50137988
PNG
(3-Hydroxy-10-keto-N-methylmorphinan | CHEMBL432120)
Show SMILES CN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C17H21NO2/c1-18-9-8-17-7-3-2-4-13(17)15(18)16(20)12-6-5-11(19)10-14(12)17/h5-6,10,13,15,19H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1
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1.20E+3n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50138003
PNG
(3-Hydroxy-10-keto-N-propargylmorphinan | CHEMBL298...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC#C)c2c1
Show InChI InChI=1S/C19H21NO2/c1-2-10-20-11-9-19-8-4-3-5-15(19)17(20)18(22)14-7-6-13(21)12-16(14)19/h1,6-7,12,15,17,21H,3-5,8-11H2/t15-,17-,19+/m0/s1
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2.30E+3n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)
BDBM50083924
PNG
(8-Hydroxy-6,11-dimethyl-3-(tetrahydro-furan-2-ylme...)
Show SMILES C[C@H]1C2N(CC3CCCO3)CC[C@]1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1S/C19H25NO3/c1-12-17-18(22)15-6-5-13(21)10-16(15)19(12,2)7-8-20(17)11-14-4-3-9-23-14/h5-6,10,12,14,17,21H,3-4,7-9,11H2,1-2H3/t12-,14?,17?,19-/m0/s1
UniProtKB/SwissProt

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2.90E+3n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from guinea pig brain membrane


J Med Chem 43: 114-22 (2000)


Article DOI: 10.1021/jm9903343
BindingDB Entry DOI: 10.7270/Q20V8DGH
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50138015
PNG
(3-Hydroxy-10-keto-N-(2-fluoroethyl)morphinan | CHE...)
Show SMILES Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCF)c2c1
Show InChI InChI=1S/C18H22FNO2/c19-8-10-20-9-7-18-6-2-1-3-14(18)16(20)17(22)13-5-4-12(21)11-15(13)18/h4-5,11,14,16,21H,1-3,6-10H2/t14-,16-,18+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50137991
PNG
(3-O-Propargyl-10-keto-N-propargylmorphinan | CHEMB...)
Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC#C)c2cc(OCC#C)ccc12
Show InChI InChI=1S/C22H23NO2/c1-3-12-23-13-11-22-10-6-5-7-18(22)20(23)21(24)17-9-8-16(15-19(17)22)25-14-4-2/h1-2,8-9,15,18,20H,5-7,10-14H2/t18-,20-,22+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50137995
PNG
(3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmor...)
Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12
Show InChI InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50137992
PNG
(3-Hydroxy-10-keto-N-(2-methoxyethyl)morphinan | CH...)
Show SMILES COCCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31
Show InChI InChI=1S/C19H25NO3/c1-23-11-10-20-9-8-19-7-3-2-4-15(19)17(20)18(22)14-6-5-13(21)12-16(14)19/h5-6,12,15,17,21H,2-4,7-11H2,1H3/t15-,17-,19+/m0/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.


J Med Chem 47: 165-74 (2003)


Article DOI: 10.1021/jm0304156
BindingDB Entry DOI: 10.7270/Q2KD1XB2
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50083924
PNG
(8-Hydroxy-6,11-dimethyl-3-(tetrahydro-furan-2-ylme...)
Show SMILES C[C@H]1C2N(CC3CCCO3)CC[C@]1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1S/C19H25NO3/c1-12-17-18(22)15-6-5-13(21)10-16(15)19(12,2)7-8-20(17)11-14-4-3-9-23-14/h5-6,10,12,14,17,21H,3-4,7-9,11H2,1-2H3/t12-,14?,17?,19-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Binding affinity towards Opioid receptor delta 1 by displacing the radioligand [3H]naltrindole from guinea pig brain membrane


J Med Chem 43: 114-22 (2000)


Article DOI: 10.1021/jm9903343
BindingDB Entry DOI: 10.7270/Q20V8DGH
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)
BDBM50021328
PNG
(3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...)
Show SMILES CCC1C2N(CC3CC3)CCC1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-15-17-18(22)14-7-6-13(21)10-16(14)19(15,2)8-9-20(17)11-12-4-5-12/h6-7,10,12,15,17,21H,3-5,8-9,11H2,1-2H3
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n/an/an/a 4.16E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND


J Med Chem 29: 531-7 (1986)


Article DOI: 10.1021/jm00154a018
BindingDB Entry DOI: 10.7270/Q2WH2QKX
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)
BDBM50021328
PNG
(3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...)
Show SMILES CCC1C2N(CC3CC3)CCC1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-15-17-18(22)14-7-6-13(21)10-16(14)19(15,2)8-9-20(17)11-12-4-5-12/h6-7,10,12,15,17,21H,3-5,8-9,11H2,1-2H3
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n/an/a 1.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND


J Med Chem 29: 531-7 (1986)


Article DOI: 10.1021/jm00154a018
BindingDB Entry DOI: 10.7270/Q2WH2QKX
More data for this
Ligand-Target Pair
Opioid receptor


(Rattus norvegicus (rat)-RAT)
BDBM50021328
PNG
(3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...)
Show SMILES CCC1C2N(CC3CC3)CCC1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-15-17-18(22)14-7-6-13(21)10-16(14)19(15,2)8-9-20(17)11-12-4-5-12/h6-7,10,12,15,17,21H,3-5,8-9,11H2,1-2H3
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n/an/a 18n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Opioid receptor mu 1 affinity against the receptor site model site 1 (mu1) by using the curve-fitting program LIGAND


J Med Chem 29: 531-7 (1986)


Article DOI: 10.1021/jm00154a018
BindingDB Entry DOI: 10.7270/Q2WH2QKX
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50021328
PNG
(3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...)
Show SMILES CCC1C2N(CC3CC3)CCC1(C)c1cc(O)ccc1C2=O
Show InChI InChI=1/C19H25NO2/c1-3-15-17-18(22)14-7-6-13(21)10-16(14)19(15,2)8-9-20(17)11-12-4-5-12/h6-7,10,12,15,17,21H,3-5,8-9,11H2,1-2H3
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n/an/an/a 0.5n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Opioid receptor mu 1 affinity against the receptor site model site 1 (mu1)


J Med Chem 29: 531-7 (1986)


Article DOI: 10.1021/jm00154a018
BindingDB Entry DOI: 10.7270/Q2WH2QKX
More data for this
Ligand-Target Pair
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