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12 similar compounds to monomer 50022163

Compile data set for download or QSAR
Wt: 242.2
BDBM50022167
Wt: 231.2
BDBM50028320
Wt: 259.3
BDBM50028333
Wt: 287.3
BDBM50078340
Wt: 315.4
BDBM50078333
Wt: 343.4
BDBM50078335
Wt: 245.2
BDBM50077606
Wt: 245.2
BDBM50405104
Wt: 259.3
BDBM50405105
Wt: 273.3
BDBM50405106
Wt: 245.2
BDBM50405107
Wt: 259.3
BDBM50405108

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50022167,50028320,50028333,50078340,50078333,50078335,50077606,50405104,50405105,50405106,50405107,50405108   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA topoisomerase III


(Bacillus subtilis)
BDBM50077606
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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190n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA polymerase IIIC


(Bacillus subtilis)
BDBM50077606
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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310n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)


Bioorg Med Chem Lett 15: 729-32 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.016
BindingDB Entry DOI: 10.7270/Q2125S58
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50077606
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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1.40E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50022167
PNG
(2-Amino-6-(indan-5-ylamino)-3H-pyrimidin-4-one | C...)
Show SMILES Nc1nc(Nc2ccc3CCCc3c2)cc(=O)[nH]1
Show InChI InChI=1S/C13H14N4O/c14-13-16-11(7-12(18)17-13)15-10-5-4-8-2-1-3-9(8)6-10/h4-7H,1-3H2,(H4,14,15,16,17,18)
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2.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration producing 50% inhibition of Bacillus subtilis DNA topoisomerase III in the presence of dATP using DNA Polymerase assay


J Med Chem 29: 676-81 (1986)


Article DOI: 10.1021/jm00155a016
BindingDB Entry DOI: 10.7270/Q2MP528D
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50028320
PNG
(6-(3-Ethyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C12H13N3O2/c1-2-8-4-3-5-9(6-8)13-10-7-11(16)15-12(17)14-10/h3-7H,2H2,1H3,(H3,13,14,15,16,17)
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2.90E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50028320
PNG
(6-(3-Ethyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C12H13N3O2/c1-2-8-4-3-5-9(6-8)13-10-7-11(16)15-12(17)14-10/h3-7H,2H2,1H3,(H3,13,14,15,16,17)
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2.90E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Bacillus subtilis DNA topoisomerase III (wild type)


J Med Chem 23: 34-8 (1980)


Article DOI: 10.1021/jm00175a007
BindingDB Entry DOI: 10.7270/Q2125RPK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405107
PNG
(CHEMBL54371)
Show SMILES CCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-4-5-10(6-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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4.20E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405108
PNG
(CHEMBL54632)
Show SMILES CCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1C
Show InChI InChI=1S/C14H17N3O2/c1-3-4-10-5-6-11(7-9(10)2)15-12-8-13(18)17-14(19)16-12/h5-8H,3-4H2,1-2H3,(H3,15,16,17,18,19)
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1.38E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405104
PNG
(CHEMBL54814)
Show SMILES CCCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C13H15N3O2/c1-2-4-9-5-3-6-10(7-9)14-11-8-12(17)16-13(18)15-11/h3,5-8H,2,4H2,1H3,(H3,14,15,16,17,18)
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1.42E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405104
PNG
(CHEMBL54814)
Show SMILES CCCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C13H15N3O2/c1-2-4-9-5-3-6-10(7-9)14-11-8-12(17)16-13(18)15-11/h3,5-8H,2,4H2,1H3,(H3,14,15,16,17,18)
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1.70E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA polymerase IIIC


(Bacillus subtilis)
BDBM50028320
PNG
(6-(3-Ethyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C12H13N3O2/c1-2-8-4-3-5-9(6-8)13-10-7-11(16)15-12(17)14-10/h3-7H,2H2,1H3,(H3,13,14,15,16,17)
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1.86E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Bacillus subtilis DNA Polymerase III/azp-12(mutant).


J Med Chem 23: 34-8 (1980)


Article DOI: 10.1021/jm00175a007
BindingDB Entry DOI: 10.7270/Q2125RPK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50028320
PNG
(6-(3-Ethyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C12H13N3O2/c1-2-8-4-3-5-9(6-8)13-10-7-11(16)15-12(17)14-10/h3-7H,2H2,1H3,(H3,13,14,15,16,17)
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1.86E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405107
PNG
(CHEMBL54371)
Show SMILES CCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-4-5-10(6-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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1.90E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405108
PNG
(CHEMBL54632)
Show SMILES CCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1C
Show InChI InChI=1S/C14H17N3O2/c1-3-4-10-5-6-11(7-9(10)2)15-12-8-13(18)17-14(19)16-12/h5-8H,3-4H2,1-2H3,(H3,15,16,17,18,19)
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9.79E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405106
PNG
(CHEMBL53109)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1C
Show InChI InChI=1S/C15H19N3O2/c1-3-4-5-11-6-7-12(8-10(11)2)16-13-9-14(19)18-15(20)17-13/h6-9H,3-5H2,1-2H3,(H3,16,17,18,19,20)
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1.32E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA polymerase IIIE


(Bacillus subtilis)
BDBM50077606
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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>3.15E+5n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)


Bioorg Med Chem Lett 15: 729-32 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.016
BindingDB Entry DOI: 10.7270/Q2125S58
More data for this
Ligand-Target Pair
DNA polymerase IIIE


(Escherichia coli)
BDBM50077606
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...)
Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)
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>3.23E+5n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory constant against DNA polymerases IIIE from Escherichia coli; (a)


Bioorg Med Chem Lett 15: 729-32 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.016
BindingDB Entry DOI: 10.7270/Q2125S58
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405105
PNG
(CHEMBL53209)
Show SMILES CCCCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-5-10-6-4-7-11(8-10)15-12-9-13(18)17-14(19)16-12/h4,6-9H,2-3,5H2,1H3,(H3,15,16,17,18,19)
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4.65E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405106
PNG
(CHEMBL53109)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1C
Show InChI InChI=1S/C15H19N3O2/c1-3-4-5-11-6-7-12(8-10(11)2)16-13-9-14(19)18-15(20)17-13/h6-9H,3-5H2,1-2H3,(H3,16,17,18,19,20)
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6.92E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50405105
PNG
(CHEMBL53209)
Show SMILES CCCCc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-5-10-6-4-7-11(8-10)15-12-9-13(18)17-14(19)16-12/h4,6-9H,2-3,5H2,1H3,(H3,15,16,17,18,19)
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6.95E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50028333
PNG
(6-(4-Butyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12-9-13(18)17-14(19)16-12/h5-9H,2-4H2,1H3,(H3,15,16,17,18,19)
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2.19E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA polymerase IIIC


(Bacillus subtilis)
BDBM50028333
PNG
(6-(4-Butyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12-9-13(18)17-14(19)16-12/h5-9H,2-4H2,1H3,(H3,15,16,17,18,19)
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2.19E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Bacillus subtilis DNA Polymerase III/azp-12(mutant).


J Med Chem 23: 34-8 (1980)


Article DOI: 10.1021/jm00175a007
BindingDB Entry DOI: 10.7270/Q2125RPK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50028333
PNG
(6-(4-Butyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12-9-13(18)17-14(19)16-12/h5-9H,2-4H2,1H3,(H3,15,16,17,18,19)
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4.95E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).


J Med Chem 27: 181-5 (1984)


Article DOI: 10.1021/jm00368a013
BindingDB Entry DOI: 10.7270/Q2Q241FK
More data for this
Ligand-Target Pair
DNA topoisomerase III


(Bacillus subtilis)
BDBM50028333
PNG
(6-(4-Butyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12-9-13(18)17-14(19)16-12/h5-9H,2-4H2,1H3,(H3,15,16,17,18,19)
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4.96E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against Bacillus subtilis DNA topoisomerase III (wild type)


J Med Chem 23: 34-8 (1980)


Article DOI: 10.1021/jm00175a007
BindingDB Entry DOI: 10.7270/Q2125RPK
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase (UNG)


(Homo sapiens (Human))
BDBM50028333
PNG
(6-(4-Butyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C14H17N3O2/c1-2-3-4-10-5-7-11(8-6-10)15-12-9-13(18)17-14(19)16-12/h5-9H,2-4H2,1H3,(H3,15,16,17,18,19)
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n/an/a 1.50E+5n/an/an/an/an/an/a



University of Massachusetts Medical Center

Curated by ChEMBL


Assay Description
Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)


J Med Chem 42: 2344-50 (1999)


Article DOI: 10.1021/jm980718d
BindingDB Entry DOI: 10.7270/Q21J98ZQ
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase (UNG)


(Homo sapiens (Human))
BDBM50078335
PNG
(6-(4-Decyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCCCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C20H29N3O2/c1-2-3-4-5-6-7-8-9-10-16-11-13-17(14-12-16)21-18-15-19(24)23-20(25)22-18/h11-15H,2-10H2,1H3,(H3,21,22,23,24,25)
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n/an/a 3.50E+4n/an/an/an/an/an/a



University of Massachusetts Medical Center

Curated by ChEMBL


Assay Description
Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylase


J Med Chem 42: 2344-50 (1999)


Article DOI: 10.1021/jm980718d
BindingDB Entry DOI: 10.7270/Q21J98ZQ
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase (UNG)


(Homo sapiens (Human))
BDBM50078340
PNG
(6-(4-Hexyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C16H21N3O2/c1-2-3-4-5-6-12-7-9-13(10-8-12)17-14-11-15(20)19-16(21)18-14/h7-11H,2-6H2,1H3,(H3,17,18,19,20,21)
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n/an/a 3.00E+4n/an/an/an/an/an/a



University of Massachusetts Medical Center

Curated by ChEMBL


Assay Description
Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)


J Med Chem 42: 2344-50 (1999)


Article DOI: 10.1021/jm980718d
BindingDB Entry DOI: 10.7270/Q21J98ZQ
More data for this
Ligand-Target Pair
Uracil-DNA glycosylase (UNG)


(Homo sapiens (Human))
BDBM50078333
PNG
(6-(4-Octyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CCCCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1
Show InChI InChI=1S/C18H25N3O2/c1-2-3-4-5-6-7-8-14-9-11-15(12-10-14)19-16-13-17(22)21-18(23)20-16/h9-13H,2-8H2,1H3,(H3,19,20,21,22,23)
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n/an/a 8.00E+3n/an/an/an/an/an/a



University of Massachusetts Medical Center

Curated by ChEMBL


Assay Description
Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylase


J Med Chem 42: 2344-50 (1999)


Article DOI: 10.1021/jm980718d
BindingDB Entry DOI: 10.7270/Q21J98ZQ
More data for this
Ligand-Target Pair