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81 similar compounds to monomer 50025367

Compile data set for download or QSAR
Wt: 402.6
BDBM50025447
Wt: 416.6
BDBM50025388
Wt: 400.5
BDBM50025372
Wt: 319.4
BDBM50025432
Wt: 359.5
BDBM50025335
Wt: 345.5
BDBM50025375
Wt: 331.4
BDBM50025442
Wt: 346.5
BDBM50025334
Wt: 373.5
BDBM50025332
Wt: 369.4
BDBM50025453
Wt: 357.5
BDBM50025419
Wt: 402.6
BDBM50025434
Wt: 404.5
BDBM50025396
Wt: 346.5
BDBM50025406
Wt: 402.6
BDBM50025363
Displayed 1 to 15 (of 80 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50025447,50025388,50025372,50025432,50025335,50025375,50025442,50025334,50025332,50025453,50025419,50025434,50025396,50025406,50025363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025332
PNG
(1,4a,6a-Trimethyl-7-(2-methyl-butyryl)-hexadecahyd...)
Show SMILES CCC(C)C(=O)[C@H]1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C24H39NO2/c1-6-15(2)22(27)19-9-8-17-16-7-10-20-24(4,14-12-21(26)25(20)5)18(16)11-13-23(17,19)3/h15-20H,6-14H2,1-5H3
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n/an/a 1.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025388
PNG
(CHEMBL1790288 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Show SMILES CCN(CC)C(=O)C(C)[C@H]1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C26H44N2O2/c1-7-28(8-2)24(30)17(3)19-10-11-20-18-9-12-22-26(5,16-14-23(29)27(22)6)21(18)13-15-25(19,20)4/h17-22H,7-16H2,1-6H3/t17?,18-,19+,20-,21-,22?,25+,26+/m0/s1
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n/an/a 13n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025406
PNG
(CHEMBL297300 | CHEMBL3349292 | N-(1,4a,6a-Trimethy...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@@H](NC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C21H34N2O2/c1-13(24)22-17-7-6-15-14-5-8-18-21(3,12-10-19(25)23(18)4)16(14)9-11-20(15,17)2/h14-18H,5-12H2,1-4H3,(H,22,24)/t14?,15?,16?,17-,18?,20?,21?/m1/s1
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n/an/a 58n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025334
PNG
(CHEMBL3349133 | CHEMBL75875 | N-(1,4a,6a-Trimethyl...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@H](NC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C21H34N2O2/c1-13(24)22-17-7-6-15-14-5-8-18-21(3,12-10-19(25)23(18)4)16(14)9-11-20(15,17)2/h14-18H,5-12H2,1-4H3,(H,22,24)
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n/an/a 270n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025419
PNG
(CHEMBL3349128 | CHEMBL74195 | Potassium; 4a,6a-dim...)
Show SMILES [K+].C[C@]12CC[C@H]3[C@@H](CCC4NC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C([O-])=O
Show InChI InChI=1S/C19H29NO3/c1-18-9-7-13-11(12(18)4-5-14(18)17(22)23)3-6-15-19(13,2)10-8-16(21)20-15/h11-15H,3-10H2,1-2H3,(H,20,21)(H,22,23)/p-1
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n/an/a 25n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025375
PNG
(7-Acetyl-1,4a,6a,8-tetramethyl-hexadecahydro-inden...)
Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@H]1C(C)=O
Show InChI InChI=1S/C22H35NO2/c1-13-12-17-15-6-7-18-21(3,11-9-19(25)23(18)5)16(15)8-10-22(17,4)20(13)14(2)24/h13,15-18,20H,6-12H2,1-5H3/t13-,15?,16?,17?,18?,20?,21?,22?/m1/s1
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n/an/a 3.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025332
PNG
(1,4a,6a-Trimethyl-7-(2-methyl-butyryl)-hexadecahyd...)
Show SMILES CCC(C)C(=O)[C@H]1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C24H39NO2/c1-6-15(2)22(27)19-9-8-17-16-7-10-20-24(4,14-12-21(26)25(20)5)18(16)11-13-23(17,19)3/h15-20H,6-14H2,1-5H3
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n/an/a 420n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025335
PNG
(4a,6a-Dimethyl-7-(2-methyl-butyryl)-hexadecahydro-...)
Show SMILES CC(C)CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C23H37NO2/c1-5-14(2)21(26)18-8-7-16-15-6-9-19-23(4,13-11-20(25)24-19)17(15)10-12-22(16,18)3/h14-19H,5-13H2,1-4H3,(H,24,25)
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n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025363
PNG
(1,5a,7a-Trimethyl-2-oxo-octadecahydro-cyclopenta[5...)
Show SMILES CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CCC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C25H42N2O2/c1-6-27(7-2)23(29)20-12-11-18-17-10-13-21-25(4,15-8-9-22(28)26(21)5)19(17)14-16-24(18,20)3/h17-21H,6-16H2,1-5H3/t17?,18?,19?,20?,21-,24?,25?/m1/s1
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n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025372
PNG
(4,10,13-Trimethyl-3-oxo-octadecahydro-4-aza-cyclop...)
Show SMILES CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C25H40N2O2/c1-6-27(7-2)23(29)19-10-9-17-15-8-11-21-25(4,18(15)12-13-24(17,19)3)20-14-16(20)22(28)26(21)5/h15-21H,6-14H2,1-5H3/t15?,16-,17?,18?,19?,20?,21-,24?,25?/m1/s1
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n/an/a 2.70E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025375
PNG
(7-Acetyl-1,4a,6a,8-tetramethyl-hexadecahydro-inden...)
Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@H]1C(C)=O
Show InChI InChI=1S/C22H35NO2/c1-13-12-17-15-6-7-18-21(3,11-9-19(25)23(18)5)16(15)8-10-22(17,4)20(13)14(2)24/h13,15-18,20H,6-12H2,1-5H3/t13-,15?,16?,17?,18?,20?,21?,22?/m1/s1
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n/an/a 290n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025388
PNG
(CHEMBL1790288 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Show SMILES CCN(CC)C(=O)C(C)[C@H]1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C26H44N2O2/c1-7-28(8-2)24(30)17(3)19-10-11-20-18-9-12-22-26(5,16-14-23(29)27(22)6)21(18)13-15-25(19,20)4/h17-22H,7-16H2,1-6H3/t17?,18-,19+,20-,21-,22?,25+,26+/m0/s1
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n/an/a 4.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025396
PNG
(1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@H](C(=O)NC(C)(C)CO)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C24H40N2O3/c1-22(2,14-27)25-21(29)18-8-7-16-15-6-9-19-24(4,13-11-20(28)26(19)5)17(15)10-12-23(16,18)3/h15-19,27H,6-14H2,1-5H3,(H,25,29)
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n/an/a 940n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025334
PNG
(CHEMBL3349133 | CHEMBL75875 | N-(1,4a,6a-Trimethyl...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@H](NC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C21H34N2O2/c1-13(24)22-17-7-6-15-14-5-8-18-21(3,12-10-19(25)23(18)4)16(14)9-11-20(15,17)2/h14-18H,5-12H2,1-4H3,(H,22,24)
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n/an/a 1.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025406
PNG
(CHEMBL297300 | CHEMBL3349292 | N-(1,4a,6a-Trimethy...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@@H](NC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C21H34N2O2/c1-13(24)22-17-7-6-15-14-5-8-18-21(3,12-10-19(25)23(18)4)16(14)9-11-20(15,17)2/h14-18H,5-12H2,1-4H3,(H,22,24)/t14?,15?,16?,17-,18?,20?,21?/m1/s1
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n/an/a 4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025434
PNG
(1,4a,6a-Trimethyl-2-oxo-octadecahydro-1-aza-chryse...)
Show SMILES CCN(CC)C(=O)[C@H]1CCC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C25H42N2O2/c1-6-27(7-2)23(29)20-10-8-9-18-17-11-12-21-25(4,16-14-22(28)26(21)5)19(17)13-15-24(18,20)3/h17-21H,6-16H2,1-5H3/t17?,18?,19?,20?,21-,24?,25?/m1/s1
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n/an/a 7.10E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025442
PNG
(7-Acetyl-1,4a,6a-trimethyl-hexadecahydro-indeno[5,...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C21H33NO2/c1-13(23)15-6-7-16-14-5-8-18-21(3,12-10-19(24)22(18)4)17(14)9-11-20(15,16)2/h14-18H,5-12H2,1-4H3
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n/an/a 210n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025419
PNG
(CHEMBL3349128 | CHEMBL74195 | Potassium; 4a,6a-dim...)
Show SMILES [K+].C[C@]12CC[C@H]3[C@@H](CCC4NC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C([O-])=O
Show InChI InChI=1S/C19H29NO3/c1-18-9-7-13-11(12(18)4-5-14(18)17(22)23)3-6-15-19(13,2)10-8-16(21)20-15/h11-15H,3-10H2,1-2H3,(H,20,21)(H,22,23)/p-1
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n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025447
PNG
(CHEMBL3085570 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Show SMILES CCN(CC)C(=O)C[C@H]1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C25H42N2O2/c1-6-27(7-2)23(29)16-17-8-10-19-18-9-11-21-25(4,15-13-22(28)26(21)5)20(18)12-14-24(17,19)3/h17-21H,6-16H2,1-5H3/t17-,18+,19+,20+,21?,24-,25-/m1/s1
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n/an/a 560n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025432
PNG
(7-Hydroxy-4a,6a-dimethyl-hexadecahydro-indeno[5,4-...)
Show SMILES CC(O)[C@H]1CC[C@H]2[C@@H]3CCC4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C18H29NO2/c1-17-10-8-16(21)19-14(17)5-3-11-12-4-6-15(20)18(12,2)9-7-13(11)17/h11-15,20H,3-10H2,1-2H3,(H,19,21)
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n/an/a 9.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Androgen receptor


(Rattus norvegicus (Rat))
BDBM50025453
PNG
(CHEMBL308530 | CHEMBL3349127 | Sodium; 2-(4a,6a-di...)
Show SMILES [Na+].CC([C@H]1CC[C@H]2[C@@H]3CCC4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C([O-])=O
Show InChI InChI=1S/C21H33NO3/c1-12(19(24)25)14-5-6-15-13-4-7-17-21(3,11-9-18(23)22-17)16(13)8-10-20(14,15)2/h12-17H,4-11H2,1-3H3,(H,22,23)(H,24,25)/p-1
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n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro antagonist activity against rat prostatic androgen receptor (AR)


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025447
PNG
(CHEMBL3085570 | N,N-Diethyl-2-(1,4a,6a-trimethyl-2...)
Show SMILES CCN(CC)C(=O)C[C@H]1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C25H42N2O2/c1-6-27(7-2)23(29)16-17-8-10-19-18-9-11-21-25(4,15-13-22(28)26(21)5)20(18)12-14-24(17,19)3/h17-21H,6-16H2,1-5H3/t17-,18+,19+,20+,21?,24-,25-/m1/s1
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n/an/a 7.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025442
PNG
(7-Acetyl-1,4a,6a-trimethyl-hexadecahydro-indeno[5,...)
Show SMILES CN1C2CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O
Show InChI InChI=1S/C21H33NO2/c1-13(23)15-6-7-16-14-5-8-18-21(3,12-10-19(24)22(18)4)17(14)9-11-20(15,16)2/h14-18H,5-12H2,1-4H3
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n/an/a 23n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Steroid 5-alpha-reductase from rat prostate


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025372
PNG
(4,10,13-Trimethyl-3-oxo-octadecahydro-4-aza-cyclop...)
Show SMILES CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C25H40N2O2/c1-6-27(7-2)23(29)19-10-9-17-15-8-11-21-25(4,18(15)12-13-24(17,19)3)20-14-16(20)22(28)26(21)5/h15-21H,6-14H2,1-5H3/t15?,16-,17?,18?,19?,20?,21-,24?,25?/m1/s1
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n/an/a 20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rat prostatic steroid 5-alpha-reductase


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair
Steroid 5-alpha-reductase


(Rattus norvegicus)
BDBM50025432
PNG
(7-Hydroxy-4a,6a-dimethyl-hexadecahydro-indeno[5,4-...)
Show SMILES CC(O)[C@H]1CC[C@H]2[C@@H]3CCC4NC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C18H29NO2/c1-17-10-8-16(21)19-14(17)5-3-11-12-4-6-15(20)18(12,2)9-7-13(11)17/h11-15,20H,3-10H2,1-2H3,(H,19,21)
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n/an/a 45n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Steroid 5-alpha-reductase from rat prostate


J Med Chem 29: 2298-315 (1986)


Article DOI: 10.1021/jm00161a028
BindingDB Entry DOI: 10.7270/Q2XG9RQR
More data for this
Ligand-Target Pair