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38 similar compounds to monomer 50232682

Compile data set for download or QSAR
Wt: 260.3
BDBM50032371
Wt: 274.4
BDBM50032376
Wt: 246.3
BDBM50032379
Purchase
Wt: 274.4
BDBM50054798
Wt: 260.3
BDBM50054800
Wt: 274.4
BDBM50054801
Wt: 302.4
BDBM50054803
Wt: 260.3
BDBM50054804
Wt: 288.4
BDBM50054805
Wt: 297.4
BDBM50207740
Wt: 297.4
BDBM50207744
Wt: 297.4
BDBM50207752
Wt: 297.4
BDBM50207755
Wt: 246.3
BDBM50275771
Purchase
Wt: 400.5
BDBM50135976
Displayed 1 to 15 (of 38 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 60 hits for monomerid = 50032371,50032376,50032379,50054798,50054800,50054801,50054803,50054804,50054805,50207740,50207744,50207752,50207755,50275771,50135976   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aromatase (CYP19)


(Homo sapiens (Human))
BDBM50135976
PNG
(CHEMBL3752998)
Show SMILES CCCCCC(=O)O[C@H]1C[C@H]2[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12
Show InChI InChI=1S/C25H36O4/c1-4-5-6-7-23(28)29-21-15-17-18-8-9-22(27)25(18,3)13-11-19(17)24(2)12-10-16(26)14-20(21)24/h14,17-19,21H,4-13,15H2,1-3H3/t17-,18-,19-,21-,24+,25-/m0/s1
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MMDB

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7n/an/an/an/an/an/an/an/a



The M. S. University of Baroda

Curated by ChEMBL


Assay Description
Competitive inhibition of human aromatase extracted from placental microsomes after 5 mins by Dixon plot analysis in presence of [1beta-3H]AD


Eur J Med Chem 105: 1-38 (2015)


Article DOI: 10.1016/j.ejmech.2015.09.038
BindingDB Entry DOI: 10.7270/Q2W66NMZ
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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8.5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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8.5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine


J Med Chem 41: 3507-14 (1998)


Article DOI: 10.1021/jm980238m
BindingDB Entry DOI: 10.7270/Q2000175
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054804
PNG
((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1
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14n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054804
PNG
((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1
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14n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine


J Med Chem 41: 3507-14 (1998)


Article DOI: 10.1021/jm980238m
BindingDB Entry DOI: 10.7270/Q2000175
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054800
PNG
((1R,2S)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@@H]1C(C)N)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m1/s1
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170n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054800
PNG
((1R,2S)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@@H]1C(C)N)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m1/s1
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170n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054804
PNG
((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1
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2.40E+3n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine


J Med Chem 41: 3507-14 (1998)


Article DOI: 10.1021/jm980238m
BindingDB Entry DOI: 10.7270/Q2000175
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054804
PNG
((1S,2R)-2-(1-Amino-ethyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(C)N)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12(3)17)13-9-7-6-8-10-13/h6-10,12,14H,4-5,11,17H2,1-3H3/t12?,14-,16+/m0/s1
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2.40E+3n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054798
PNG
((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Show SMILES CCC(N)[C@@H]1C[C@@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-4-15(18)14-12-17(14,13-10-8-7-9-11-13)16(20)19(5-2)6-3/h7-11,14-15H,4-6,12,18H2,1-3H3/t14-,15?,17+/m0/s1
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2.40E+4n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054798
PNG
((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Show SMILES CCC(N)[C@@H]1C[C@@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-4-15(18)14-12-17(14,13-10-8-7-9-11-13)16(20)19(5-2)6-3/h7-11,14-15H,4-6,12,18H2,1-3H3/t14-,15?,17+/m0/s1
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2.40E+4n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054805
PNG
((1S,2R)-2-(1-Amino-butyl)-1-phenyl-cyclopropanecar...)
Show SMILES CCCC(N)[C@@H]1C[C@@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C18H28N2O/c1-4-10-16(19)15-13-18(15,14-11-8-7-9-12-14)17(21)20(5-2)6-3/h7-9,11-12,15-16H,4-6,10,13,19H2,1-3H3/t15-,16?,18+/m0/s1
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3.70E+4n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054798
PNG
((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Show SMILES CCC(N)[C@@H]1C[C@@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-4-15(18)14-12-17(14,13-10-8-7-9-11-13)16(20)19(5-2)6-3/h7-11,14-15H,4-6,12,18H2,1-3H3/t14-,15?,17+/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine


J Med Chem 41: 3507-14 (1998)


Article DOI: 10.1021/jm980238m
BindingDB Entry DOI: 10.7270/Q2000175
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054803
PNG
((1S,2R)-2-(1-Amino-3-methyl-butyl)-1-phenyl-cyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C(N)CC(C)C)c1ccccc1
Show InChI InChI=1S/C19H30N2O/c1-5-21(6-2)18(22)19(15-10-8-7-9-11-15)13-16(19)17(20)12-14(3)4/h7-11,14,16-17H,5-6,12-13,20H2,1-4H3/t16-,17?,19+/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054801
PNG
((1R,2S)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Show SMILES CCC(N)[C@H]1C[C@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-4-15(18)14-12-17(14,13-10-8-7-9-11-13)16(20)19(5-2)6-3/h7-11,14-15H,4-6,12,18H2,1-3H3/t14-,15?,17+/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054801
PNG
((1R,2S)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Show SMILES CCC(N)[C@H]1C[C@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-4-15(18)14-12-17(14,13-10-8-7-9-11-13)16(20)19(5-2)6-3/h7-11,14-15H,4-6,12,18H2,1-3H3/t14-,15?,17+/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of [3H]-paroxetine binding on serotonin transporter of rat cerebral cortical synaptic membrane


J Med Chem 39: 4844-52 (1997)


Article DOI: 10.1021/jm960495w
BindingDB Entry DOI: 10.7270/Q2M907R2
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50054798
PNG
((1S,2R)-2-(1-Amino-propyl)-1-phenyl-cyclopropaneca...)
Show SMILES CCC(N)[C@@H]1C[C@@]1(C(=O)N(CC)CC)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-4-15(18)14-12-17(14,13-10-8-7-9-11-13)16(20)19(5-2)6-3/h7-11,14-15H,4-6,12,18H2,1-3H3/t14-,15?,17+/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of Serotonin transporter in cerebral cortical synaptic membrane of rats using [3H]-paroxetine


J Med Chem 41: 3507-14 (1998)


Article DOI: 10.1021/jm980238m
BindingDB Entry DOI: 10.7270/Q2000175
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 320n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SERT


Bioorg Med Chem Lett 18: 3328-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.025
BindingDB Entry DOI: 10.7270/Q21V5FTK
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 77n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human NET


Bioorg Med Chem Lett 18: 3328-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.025
BindingDB Entry DOI: 10.7270/Q21V5FTK
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 3.20E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


Bioorg Med Chem Lett 18: 3328-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.025
BindingDB Entry DOI: 10.7270/Q21V5FTK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 420n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SERT


Bioorg Med Chem Lett 18: 3328-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.025
BindingDB Entry DOI: 10.7270/Q21V5FTK
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 6.10E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


Bioorg Med Chem Lett 18: 3328-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.025
BindingDB Entry DOI: 10.7270/Q21V5FTK
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 40n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells


Bioorg Med Chem Lett 18: 3230-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 3.20E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of dopamine uptake at human DAT expressed in HEK293 cells


Bioorg Med Chem Lett 18: 3230-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 320n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of serotonin uptake at human SERT expressed in HEK293 cells


Bioorg Med Chem Lett 18: 3230-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.045
BindingDB Entry DOI: 10.7270/Q2D21ZG8
More data for this
Ligand-Target Pair
Transporter


(Rattus norvegicus (rat))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 100n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of radiolabeled noradrenaline uptake from rat brain NET


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Transporter


(Rattus norvegicus (rat))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 30n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of Levo[ring-2,5,6-3H]norepinephrine from rat synaptosomal NET expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50032376
PNG
((1S,2R)-2-Dimethylaminomethyl-1-phenyl-cyclopropan...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN(C)C)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-5-19(6-2)16(20)17(12-15(17)13-18(3)4)14-10-8-7-9-11-14/h7-11,15H,5-6,12-13H2,1-4H3/t15-,17+/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50032371
PNG
((1S,2R)-2-Methylaminomethyl-1-phenyl-cyclopropanec...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CNC)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12-17-3)13-9-7-6-8-10-13/h6-10,14,17H,4-5,11-12H2,1-3H3/t14-,16+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Transporter


(Rattus norvegicus (rat))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a 16n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of Levo[ring-2,5,6-3H]norepinephrine from rat synaptosomal NET expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a 28n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [alpha,beta-3H(N)]-5-hydroxytryptamine from rat synaptosomal SERT expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a 40n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of Levo[ring-2,5,6-3H]norepinephrine from human cloned NET expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a 320n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [alpha,beta-3H(N)]-5-hydroxytryptamine from human cloned SERT expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a 3.20E+3n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of 3,4-[ring-2,5,6-3H]dihydroxyphenylethylamine from human cloned DAT expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a 2.00E+4n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of 3,4-[ring-2,5,6-3H]dihydroxyphenylethylamine from rat synaptosomal DAT expressed in HEK293 cells by microplate scintillation counter


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50275771
PNG
(1S,2R-milnacipran | CHEMBL471001)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human ERG expressed in HEK293 cells by patch-clamp method


J Med Chem 51: 7265-72 (2009)


Article DOI: 10.1021/jm8009537
BindingDB Entry DOI: 10.7270/Q2H41SCG
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 77n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human NET


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 420n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SERT


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Monoamine transporters; serotonin & dopamine


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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n/an/a 6.10E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50032371
PNG
((1S,2R)-2-Methylaminomethyl-1-phenyl-cyclopropanec...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CNC)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12-17-3)13-9-7-6-8-10-13/h6-10,14,17H,4-5,11-12H2,1-3H3/t14-,16+/m0/s1
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n/an/a 6.50E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human NET


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50032371
PNG
((1S,2R)-2-Methylaminomethyl-1-phenyl-cyclopropanec...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CNC)c1ccccc1
Show InChI InChI=1S/C16H24N2O/c1-4-18(5-2)15(19)16(11-14(16)12-17-3)13-9-7-6-8-10-13/h6-10,14,17H,4-5,11-12H2,1-3H3/t14-,16+/m0/s1
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n/an/a 5.40E+3n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SERT


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50032376
PNG
((1S,2R)-2-Dimethylaminomethyl-1-phenyl-cyclopropan...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN(C)C)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-5-19(6-2)16(20)17(12-15(17)13-18(3)4)14-10-8-7-9-11-14/h7-11,15H,5-6,12-13H2,1-4H3/t15-,17+/m0/s1
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PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human NET


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50032379
PNG
((1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclop...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)c1ccccc1
Show InChI InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
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PubMed
n/an/a 40n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human NET


Bioorg Med Chem Lett 18: 3328-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.025
BindingDB Entry DOI: 10.7270/Q21V5FTK
More data for this
Ligand-Target Pair
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50207744
PNG
(CHEMBL389597 | [(1R,2S)-2-(diethylcarbamoyl)-2-(na...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C[NH3+])c1ccc2ccccc2c1
Show InChI InChI=1S/C19H24N2O/c1-3-21(4-2)18(22)19(12-17(19)13-20)16-10-9-14-7-5-6-8-15(14)11-16/h5-11,17H,3-4,12-13,20H2,1-2H3/p+1/t17-,19+/m0/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT uptake at DA transporter in Wistar rat synaptosomes


Bioorg Med Chem Lett 17: 2834-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.054
BindingDB Entry DOI: 10.7270/Q2H994W3
More data for this
Ligand-Target Pair
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50207744
PNG
(CHEMBL389597 | [(1R,2S)-2-(diethylcarbamoyl)-2-(na...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C[NH3+])c1ccc2ccccc2c1
Show InChI InChI=1S/C19H24N2O/c1-3-21(4-2)18(22)19(12-17(19)13-20)16-10-9-14-7-5-6-8-15(14)11-16/h5-11,17H,3-4,12-13,20H2,1-2H3/p+1/t17-,19+/m0/s1
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n/an/a 29n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT uptake at NE transporter in Wistar rat synaptosomes


Bioorg Med Chem Lett 17: 2834-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.054
BindingDB Entry DOI: 10.7270/Q2H994W3
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50032376
PNG
((1S,2R)-2-Dimethylaminomethyl-1-phenyl-cyclopropan...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN(C)C)c1ccccc1
Show InChI InChI=1S/C17H26N2O/c1-5-19(6-2)16(20)17(12-15(17)13-18(3)4)14-10-8-7-9-11-14/h7-11,15H,5-6,12-13H2,1-4H3/t15-,17+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Neurocrine Bioscience, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SERT


Bioorg Med Chem Lett 18: 1346-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.011
BindingDB Entry DOI: 10.7270/Q2S183BV
More data for this
Ligand-Target Pair
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50207740
PNG
(CHEMBL234495 | [(1R,2S)-2-(diethylcarbamoyl)-2-(na...)
Show SMILES CCN(CC)C(=O)[C@]1(C[C@H]1C[NH3+])c1cccc2ccccc12
Show InChI InChI=1S/C19H24N2O/c1-3-21(4-2)18(22)19(12-15(19)13-20)17-11-7-9-14-8-5-6-10-16(14)17/h5-11,15H,3-4,12-13,20H2,1-2H3/p+1/t15-,19-/m0/s1
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n/an/a 370n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT uptake at NE transporter in Wistar rat synaptosomes


Bioorg Med Chem Lett 17: 2834-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.054
BindingDB Entry DOI: 10.7270/Q2H994W3
More data for this
Ligand-Target Pair
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50207755
PNG
(CHEMBL233645 | [(1S,2R)-2-(diethylcarbamoyl)-2-(na...)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@@H]1C[NH3+])c1cccc2ccccc12
Show InChI InChI=1S/C19H24N2O/c1-3-21(4-2)18(22)19(12-15(19)13-20)17-11-7-9-14-8-5-6-10-16(14)17/h5-11,15H,3-4,12-13,20H2,1-2H3/p+1/t15-,19-/m1/s1
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n/an/a 200n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT uptake at NE transporter in Wistar rat synaptosomes


Bioorg Med Chem Lett 17: 2834-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.054
BindingDB Entry DOI: 10.7270/Q2H994W3
More data for this
Ligand-Target Pair
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50207752
PNG
(CHEMBL388657 | [(1S,2R)-2-(diethylcarbamoyl)-2-(na...)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@@H]1C[NH3+])c1ccc2ccccc2c1
Show InChI InChI=1S/C19H24N2O/c1-3-21(4-2)18(22)19(12-17(19)13-20)16-10-9-14-7-5-6-8-15(14)11-16/h5-11,17H,3-4,12-13,20H2,1-2H3/p+1/t17-,19+/m1/s1
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n/an/a 140n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT uptake at DA transporter in Wistar rat synaptosomes


Bioorg Med Chem Lett 17: 2834-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.054
BindingDB Entry DOI: 10.7270/Q2H994W3
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50207755
PNG
(CHEMBL233645 | [(1S,2R)-2-(diethylcarbamoyl)-2-(na...)
Show SMILES CCN(CC)C(=O)[C@@]1(C[C@@H]1C[NH3+])c1cccc2ccccc12
Show InChI InChI=1S/C19H24N2O/c1-3-21(4-2)18(22)19(12-15(19)13-20)17-11-7-9-14-8-5-6-10-16(14)17/h5-11,15H,3-4,12-13,20H2,1-2H3/p+1/t15-,19-/m1/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



University of Oslo

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT uptake at 5HT transporter in Wistar rat synaptosomes


Bioorg Med Chem Lett 17: 2834-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.054
BindingDB Entry DOI: 10.7270/Q2H994W3
More data for this
Ligand-Target Pair
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