BindingDB logo
myBDB logout

13 molecules are shown

Wt: 355.5
BDBM50032500
Purchase
Wt: 212.3
BDBM50294112
Wt: 226.3
BDBM50294113
Wt: 170.2
BDBM50294114
Wt: 168.2
BDBM50294095
Wt: 254.4
BDBM50294097
Wt: 198.3
BDBM50294098
Wt: 423.6
BDBM50294104
Wt: 409.6
BDBM50294105
Wt: 409.6
BDBM50294106
Wt: 423.6
BDBM50294107
Wt: 393.6
BDBM50294109
Wt: 491.7
BDBM50294110

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50032500,50294112,50294113,50294114,50294095,50294097,50294098,50294104,50294105,50294106,50294107,50294109,50294110   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyamine oxidase


(Zea mays)
BDBM50294105
PNG
(1-(Guanidino)-17-(N1-(methylcyclopropyl)guanidino)...)
Show SMILES NC(N)=NCCCCCCCCNCCCCCCCCN=C(N)NCC1CC1
Show InChI InChI=1S/C22H47N7/c23-21(24)27-17-11-7-3-1-5-9-15-26-16-10-6-2-4-8-12-18-28-22(25)29-19-20-13-14-20/h20,26H,1-19H2,(H4,23,24,27)(H3,25,28,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.0800n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294107
PNG
(1-(Guanidino)-17-(N1-(beta-methylallyl)guanidino)-...)
Show SMILES CC(=C)CCNC(N)=NCCCCCCCCNCCCCCCCCN=C(N)N
Show InChI InChI=1S/C23H49N7/c1-21(2)15-20-30-23(26)29-19-14-10-6-4-8-12-17-27-16-11-7-3-5-9-13-18-28-22(24)25/h27H,1,3-20H2,2H3,(H4,24,25,28)(H3,26,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.5n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294109
PNG
(1-(Guanidino)-17-(N1-(propargyl)guanidino)-9-azahe...)
Show SMILES NC(N)=NCCCCCCCCNCCCCCCCCN=C(N)NCC#C
Show InChI InChI=1S/C21H43N7/c1-2-15-27-21(24)28-19-14-10-6-4-8-12-17-25-16-11-7-3-5-9-13-18-26-20(22)23/h1,25H,3-19H2,(H4,22,23,26)(H3,24,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.700n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294106
PNG
(1-(Guanidino)-17-(N1-(gamma-methylallyl)guanidino)...)
Show SMILES C\C=C\CNC(N)=NCCCCCCCCNCCCCCCCCN=C(N)N
Show InChI InChI=1S/C22H47N7/c1-2-3-18-28-22(25)29-20-15-11-7-5-9-13-17-26-16-12-8-4-6-10-14-19-27-21(23)24/h2-3,26H,4-20H2,1H3,(H4,23,24,27)(H3,25,28,29)/b3-2+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.10n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294110
PNG
(1,1'-(8,8'-azanediylbis(octane-8,1-diyl))bis(3-(3-...)
Show SMILES CC(C)=CCNC(N)=NCCCCCCCCNCCCCCCCCNC(N)=NCC=C(C)C
Show InChI InChI=1S/C28H57N7/c1-25(2)17-23-34-27(29)32-21-15-11-7-5-9-13-19-31-20-14-10-6-8-12-16-22-33-28(30)35-24-18-26(3)4/h17-18,31H,5-16,19-24H2,1-4H3,(H3,29,32,34)(H3,30,33,35)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.70n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294104
PNG
(1-(Guanidino)-17-(N1-(gamma,gamma-dimethylallyl)gu...)
Show SMILES CC(C)=CCNC(N)=NCCCCCCCCNCCCCCCCCN=C(N)N
Show InChI InChI=1S/C23H49N7/c1-21(2)15-20-30-23(26)29-19-14-10-6-4-8-12-17-27-16-11-7-3-5-9-13-18-28-22(24)25/h15,27H,3-14,16-20H2,1-2H3,(H4,24,25,28)(H3,26,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50032500
PNG
(1,1'-(8,8'-azanediylbis(octane-8,1-diyl))diguanidi...)
Show SMILES NC(=N)NCCCCCCCCNCCCCCCCCNC(N)=N
Show InChI InChI=1S/C18H41N7/c19-17(20)24-15-11-7-3-1-5-9-13-23-14-10-6-2-4-8-12-16-25-18(21)22/h23H,1-16H2,(H4,19,20,24)(H4,21,22,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
7.5n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Polyamine oxidase


(Zea mays)
BDBM50294112
PNG
(1-(5-aminopentyl)-3-(3-methylbut-2-enyl)guanidine ...)
Show SMILES CC(C)=CCNC(N)=NCCCCCN
Show InChI InChI=1S/C11H24N4/c1-10(2)6-9-15-11(13)14-8-5-3-4-7-12/h6H,3-5,7-9,12H2,1-2H3,(H3,13,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
10n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294113
PNG
(1-(6-aminohexyl)-3-(3-methylbut-2-enyl)guanidine |...)
Show SMILES CC(C)=CCNC(N)=NCCCCCCN
Show InChI InChI=1S/C12H26N4/c1-11(2)7-10-16-12(14)15-9-6-4-3-5-8-13/h7H,3-6,8-10,13H2,1-2H3,(H3,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
22n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294114
PNG
(1-allyl-3-(4-aminobutyl)guanidine | CHEMBL541766)
Show SMILES NCCCCN=C(N)NCC=C
Show InChI InChI=1S/C8H18N4/c1-2-6-11-8(10)12-7-4-3-5-9/h2H,1,3-7,9H2,(H3,10,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
130n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294095
PNG
(1-(4-aminobutyl)-3-(prop-2-ynyl)guanidine | CHEMBL...)
Show SMILES NCCCCN=C(N)NCC#C
Show InChI InChI=1S/C8H16N4/c1-2-6-11-8(10)12-7-4-3-5-9/h1H,3-7,9H2,(H3,10,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
250n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294097
PNG
(CHEMBL550629 | N1-(5-Aminopentyl)-N3-(cyclohexylet...)
Show SMILES NCCCCCN=C(N)NCCC1CCCCC1
Show InChI InChI=1S/C14H30N4/c15-10-5-2-6-11-17-14(16)18-12-9-13-7-3-1-4-8-13/h13H,1-12,15H2,(H3,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.72E+3n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Polyamine oxidase


(Zea mays)
BDBM50294098
PNG
(CHEMBL552343 | N1-(5-Aminopentyl)-N3-(cyclopropylm...)
Show SMILES NCCCCCN=C(N)NCC1CC1
Show InChI InChI=1S/C10H22N4/c11-6-2-1-3-7-13-10(12)14-8-9-4-5-9/h9H,1-8,11H2,(H3,12,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.58E+3n/an/an/an/an/an/a6.5n/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method


J Med Chem 52: 4774-85 (2009)


Article DOI: 10.1021/jm900371z
BindingDB Entry DOI: 10.7270/Q2TB16W1
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Deoxyhypusine synthase


(Rattus norvegicus)
BDBM50032500
PNG
(1,1'-(8,8'-azanediylbis(octane-8,1-diyl))diguanidi...)
Show SMILES NC(=N)NCCCCCCCCNCCCCCCCCNC(N)=N
Show InChI InChI=1S/C18H41N7/c19-17(20)24-15-11-7-3-1-5-9-13-23-14-10-6-2-4-8-12-16-25-18(21)22/h23H,1-16H2,(H4,19,20,24)(H4,21,22,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



National Institute of Dental Research

Curated by ChEMBL


Assay Description
In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.


J Med Chem 38: 3053-61 (1995)


Article DOI: 10.1021/jm00016a008
BindingDB Entry DOI: 10.7270/Q2P55MJ2
More data for this
Ligand-Target Pair