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4 similar compounds to monomer 50284125

Compile data set for download or QSAR
Wt: 485.5
BDBM50033746
Wt: 511.6
BDBM50284121
Wt: 513.6
BDBM50284122
Wt: 499.5
BDBM50284123

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50033746,50284121,50284122,50284123   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(Homo sapiens (Human))
BDBM50033746
PNG
(7-[3-(4-Carbamoyl-3-methoxy-2-propyl-phenoxy)-prop...)
Show SMILES CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(N)=O)c1OC
Show InChI InChI=1S/C27H35NO7/c1-4-7-18-21(12-9-17-10-13-23(27(30)31)35-24(17)18)33-15-6-16-34-22-14-11-20(26(28)29)25(32-3)19(22)8-5-2/h9,11-12,14,23H,4-8,10,13,15-16H2,1-3H3,(H2,28,29)(H,30,31)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for Leukotriene B4 (LTB4) receptor


J Med Chem 38: 858-68 (1995)


Article DOI: 10.1021/jm00006a002
BindingDB Entry DOI: 10.7270/Q22806N0
More data for this
Ligand-Target Pair
LTB4R


(Homo sapiens (Human))
BDBM50284121
PNG
(7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcarbam...)
Show SMILES CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C29H37NO7/c1-4-6-20-23(12-9-19-10-13-25(29(32)33)37-26(19)20)35-15-5-16-36-24-14-11-21(28(31)30-2)27(34-3)22(24)17-18-7-8-18/h9,11-12,14,18,25H,4-8,10,13,15-17H2,1-3H3,(H,30,31)(H,32,33)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 5.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against leukotriene B4 receptor


Bioorg Med Chem Lett 4: 811-816 (1994)


Article DOI: 10.1016/S0960-894X(01)80853-2
BindingDB Entry DOI: 10.7270/Q2DN451X
More data for this
Ligand-Target Pair
LTB4R


(Homo sapiens (Human))
BDBM50033746
PNG
(7-[3-(4-Carbamoyl-3-methoxy-2-propyl-phenoxy)-prop...)
Show SMILES CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(N)=O)c1OC
Show InChI InChI=1S/C27H35NO7/c1-4-7-18-21(12-9-17-10-13-23(27(30)31)35-24(17)18)33-15-6-16-34-22-14-11-20(26(28)29)25(32-3)19(22)8-5-2/h9,11-12,14,23H,4-8,10,13,15-16H2,1-3H3,(H2,28,29)(H,30,31)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 2.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against leukotriene B4 receptor


Bioorg Med Chem Lett 4: 811-816 (1994)


Article DOI: 10.1016/S0960-894X(01)80853-2
BindingDB Entry DOI: 10.7270/Q2DN451X
More data for this
Ligand-Target Pair
LTB4R


(Homo sapiens (Human))
BDBM50284123
PNG
(7-[3-(3-Methoxy-4-methylcarbamoyl-2-propyl-phenoxy...)
Show SMILES CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(=O)NC)c1OC
Show InChI InChI=1S/C28H37NO7/c1-5-8-19-22(13-10-18-11-14-24(28(31)32)36-25(18)19)34-16-7-17-35-23-15-12-21(27(30)29-3)26(33-4)20(23)9-6-2/h10,12-13,15,24H,5-9,11,14,16-17H2,1-4H3,(H,29,30)(H,31,32)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 0.850n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against leukotriene B4 receptor


Bioorg Med Chem Lett 4: 811-816 (1994)


Article DOI: 10.1016/S0960-894X(01)80853-2
BindingDB Entry DOI: 10.7270/Q2DN451X
More data for this
Ligand-Target Pair
LTB4R


(Homo sapiens (Human))
BDBM50284122
PNG
(7-[3-(4-Dimethylcarbamoyl-3-methoxy-2-propyl-pheno...)
Show SMILES CCCc1c(OCCCOc2ccc3CCC(Oc3c2CCC)C(O)=O)ccc(C(=O)N(C)C)c1OC
Show InChI InChI=1S/C29H39NO7/c1-6-9-20-23(14-11-19-12-15-25(29(32)33)37-26(19)20)35-17-8-18-36-24-16-13-22(28(31)30(3)4)27(34-5)21(24)10-7-2/h11,13-14,16,25H,6-10,12,15,17-18H2,1-5H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 0.150n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against leukotriene B4 receptor


Bioorg Med Chem Lett 4: 811-816 (1994)


Article DOI: 10.1016/S0960-894X(01)80853-2
BindingDB Entry DOI: 10.7270/Q2DN451X
More data for this
Ligand-Target Pair