BindingDB logo
myBDB logout

2 similar compounds to monomer 50034283

Compile data set for download or QSAR
Wt: 354.4
BDBM50034305
Wt: 368.4
BDBM50034307

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034305,50034307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034307
PNG
(CHEMBL23912 | N-{4-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccnc2)CC1
Show InChI InChI=1S/C21H28N4O2/c1-27-20-9-3-2-8-19(20)25-15-13-24(14-16-25)12-5-4-11-23-21(26)18-7-6-10-22-17-18/h2-3,6-10,17H,4-5,11-16H2,1H3,(H,23,26)
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
25.2n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50034305
PNG
(CHEMBL24113 | N-{3-[4-(2-Methoxy-phenyl)-piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cccnc2)CC1
Show InChI InChI=1S/C20H26N4O2/c1-26-19-8-3-2-7-18(19)24-14-12-23(13-15-24)11-5-10-22-20(25)17-6-4-9-21-16-17/h2-4,6-9,16H,5,10-15H2,1H3,(H,22,25)
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
321n/an/an/an/an/an/an/an/a



FAES, S.A.

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.


J Med Chem 38: 1273-7 (1995)


Article DOI: 10.1021/jm00008a005
BindingDB Entry DOI: 10.7270/Q2H9947K
More data for this
Ligand-Target Pair