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18 similar compounds to monomer 50010895

Compile data set for download or QSAR
Wt: 350.9
BDBM50456203
Wt: 326.4
BDBM50036656
Wt: 366.5
BDBM50368732
Wt: 330.4
BDBM50368734
Wt: 370.5
BDBM50368735
Wt: 342.4
BDBM50368736
Wt: 328.4
BDBM50368715
Wt: 286.3
BDBM50368714
Wt: 328.4
BDBM50368716
Wt: 314.4
BDBM50368720
Wt: 336.4
BDBM50368721
Wt: 300.4
BDBM50368722
Wt: 328.4
BDBM50368724
Wt: 330.4
BDBM50368725
Wt: 336.4
BDBM50368727
Displayed 1 to 15 (of 18 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50456203,50036656,50368732,50368734,50368735,50368736,50368715,50368714,50368716,50368720,50368721,50368722,50368724,50368725,50368727   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50456203
PNG
(CHEMBL2092955)
Show SMILES O=C(NC1CCCCC1)[C@@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C18H22N2OS.ClH/c21-18(20-12-6-2-1-3-7-12)15-10-14-13-8-4-5-9-16(13)22-17(14)11-19-15;/h4-5,8-9,12,15,19H,1-3,6-7,10-11H2,(H,20,21);1H/t15-;/m0./s1
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n/an/a>5.00E+3n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368736
PNG
(CHEMBL1203188)
Show SMILES O=C(NC1CCCCCCC1)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C20H26N2OS/c23-20(22-14-8-4-2-1-3-5-9-14)17-12-16-15-10-6-7-11-18(15)24-19(16)13-21-17/h6-7,10-11,14,17,21H,1-5,8-9,12-13H2,(H,22,23)/t17-/m1/s1
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n/an/a 23n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50036656
PNG
(1,2,3,4-Tetrahydro-benzo[4,5]thieno[2,3-c]pyridine...)
Show SMILES O=C(NC1CC2CCC1C2)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C19H22N2OS/c22-19(21-15-8-11-5-6-12(15)7-11)16-9-14-13-3-1-2-4-17(13)23-18(14)10-20-16/h1-4,11-12,15-16,20H,5-10H2,(H,21,22)/t11?,12?,15?,16-/m1/s1
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n/an/a 66n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368715
PNG
(CHEMBL1203194)
Show SMILES CC1CCCCC1NC(=O)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C19H24N2OS/c1-12-6-2-4-8-15(12)21-19(22)16-10-14-13-7-3-5-9-17(13)23-18(14)11-20-16/h3,5,7,9,12,15-16,20H,2,4,6,8,10-11H2,1H3,(H,21,22)/t12?,15?,16-/m1/s1
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n/an/a 28n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368716
PNG
(CHEMBL1203193)
Show SMILES CC1CCC(CC1)NC(=O)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C19H24N2OS/c1-12-6-8-13(9-7-12)21-19(22)16-10-15-14-4-2-3-5-17(14)23-18(15)11-20-16/h2-5,12-13,16,20H,6-11H2,1H3,(H,21,22)/t12?,13?,16-/m1/s1
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n/an/a 32n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368721
PNG
(CHEMBL1203199)
Show SMILES C[C@H](NC(=O)[C@H]1Cc2c(CN1)sc1ccccc21)c1ccccc1
Show InChI InChI=1S/C20H20N2OS/c1-13(14-7-3-2-4-8-14)22-20(23)17-11-16-15-9-5-6-10-18(15)24-19(16)12-21-17/h2-10,13,17,21H,11-12H2,1H3,(H,22,23)/t13-,17+/m0/s1
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n/an/a 58n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368722
PNG
(CHEMBL1203157)
Show SMILES O=C(NC1CCCC1)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C17H20N2OS/c20-17(19-11-5-1-2-6-11)14-9-13-12-7-3-4-8-15(12)21-16(13)10-18-14/h3-4,7-8,11,14,18H,1-2,5-6,9-10H2,(H,19,20)/t14-/m1/s1
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n/an/a 111n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368724
PNG
(CHEMBL1203171)
Show SMILES O=C(NCC1CCCCC1)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C19H24N2OS/c22-19(21-11-13-6-2-1-3-7-13)16-10-15-14-8-4-5-9-17(14)23-18(15)12-20-16/h4-5,8-9,13,16,20H,1-3,6-7,10-12H2,(H,21,22)/t16-/m1/s1
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n/an/a 20n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368725
PNG
(CHEMBL1203180)
Show SMILES CCCCCCCNC(=O)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C19H26N2OS/c1-2-3-4-5-8-11-20-19(22)16-12-15-14-9-6-7-10-17(14)23-18(15)13-21-16/h6-7,9-10,16,21H,2-5,8,11-13H2,1H3,(H,20,22)/t16-/m1/s1
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n/an/a 126n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against 5-hydroxytryptamine 1A receptor


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368727
PNG
(CHEMBL1203196)
Show SMILES Cc1ccc(CNC(=O)[C@H]2Cc3c(CN2)sc2ccccc32)cc1
Show InChI InChI=1S/C20H20N2OS/c1-13-6-8-14(9-7-13)11-22-20(23)17-10-16-15-4-2-3-5-18(15)24-19(16)12-21-17/h2-9,17,21H,10-12H2,1H3,(H,22,23)/t17-/m1/s1
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n/an/a 133n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368732
PNG
(CHEMBL1203191)
Show SMILES O=C(NC12CC3CC(CC(C3)C1)C2)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C22H26N2OS/c25-21(24-22-9-13-5-14(10-22)7-15(6-13)11-22)18-8-17-16-3-1-2-4-19(16)26-20(17)12-23-18/h1-4,13-15,18,23H,5-12H2,(H,24,25)/t13?,14?,15?,18-,22?/m1/s1
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n/an/a 62n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368734
PNG
(CHEMBL1203162)
Show SMILES OC1CCCCC1NC(=O)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C18H22N2O2S/c21-15-7-3-2-6-13(15)20-18(22)14-9-12-11-5-1-4-8-16(11)23-17(12)10-19-14/h1,4-5,8,13-15,19,21H,2-3,6-7,9-10H2,(H,20,22)/t13?,14-,15?/m1/s1
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n/an/a 149n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368720
PNG
(CHEMBL1203158)
Show SMILES O=C(NC1CCCCC1)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C18H22N2OS/c21-18(20-12-6-2-1-3-7-12)15-10-14-13-8-4-5-9-16(13)22-17(14)11-19-15/h4-5,8-9,12,15,19H,1-3,6-7,10-11H2,(H,20,21)/t15-/m1/s1
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n/an/a 27n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368735
PNG
(CHEMBL1203192)
Show SMILES CC(C)(C)C1CCC(CC1)NC(=O)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C22H30N2OS/c1-22(2,3)14-8-10-15(11-9-14)24-21(25)18-12-17-16-6-4-5-7-19(16)26-20(17)13-23-18/h4-7,14-15,18,23H,8-13H2,1-3H3,(H,24,25)/t14?,15?,18-/m1/s1
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n/an/a 53n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))
BDBM50368714
PNG
(CHEMBL1203181)
Show SMILES O=C(NC1CCC1)[C@H]1Cc2c(CN1)sc1ccccc21
Show InChI InChI=1S/C16H18N2OS/c19-16(18-10-4-3-5-10)13-8-12-11-6-1-2-7-14(11)20-15(12)9-17-13/h1-2,6-7,10,13,17H,3-5,8-9H2,(H,18,19)/t13-/m1/s1
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n/an/a 232n/an/an/an/an/an/a



Asahi Chemical Industry Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity by measuring displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus


J Med Chem 36: 3526-32 (1994)


Article DOI: 10.1021/jm00075a006
BindingDB Entry DOI: 10.7270/Q2D21Z74
More data for this
Ligand-Target Pair