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16 similar compounds to monomer 82368

Compile data set for download or QSAR
Wt: 400.5
BDBM50036855
Wt: 428.5
BDBM50036856
Wt: 444.5
BDBM50036865
Wt: 400.5
BDBM50036870
Wt: 414.5
BDBM50036871
Wt: 457.6
BDBM50036872
Wt: 456.6
BDBM50036873
Wt: 416.5
BDBM50036849
Wt: 428.5
BDBM50036850
Wt: 412.5
BDBM50036851
Wt: 414.5
BDBM50036852
Wt: 440.5
BDBM50054143
Wt: 454.6
BDBM50054147
Wt: 410.5
BDBM50054154
Wt: 468.6
BDBM50054155
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 106 hits for monomerid = 50036855,50036856,50036865,50036870,50036871,50036872,50036873,50036849,50036850,50036851,50036852,50054143,50054147,50054154,50054155   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 2a (5-HT2a) receptor


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 3.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidus


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 1n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 3.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 in calf striatum


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
adrenergic Alpha2


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-2 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 100n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against D2 receptor in calf caudate nucleus


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 1.31E+4n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Displacement of [3H]-SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 3.11E+4n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSB


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 2.24E+4n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Displacement of [3H]-raclopride from Dopamine receptor D1 of calf striatum


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 1.15E+3n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 1.13E+4n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Displacement of [3H]-SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50054147
PNG
(8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-...)
Show SMILES COc1cccc2OCC3(CCCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C27H38N2O4/c1-32-22-9-8-10-23-21(22)17-27(20-33-23)13-4-5-14-28(27)15-6-7-16-29-24(30)18-26(19-25(29)31)11-2-3-12-26/h8-10H,2-7,11-20H2,1H3
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n/an/a 2.34E+4n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Displacement of [3H]-raclopride from Dopamine receptor D1 of calf striatum


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 2.33E+4n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Displacement of [3H]-raclopride from Dopamine receptor D1 of calf striatum


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 3.80E+3n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSB


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50054154
PNG
(8-[4-spiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydr...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCCC11COc2ccccc2C1
Show InChI InChI=1S/C25H34N2O3/c28-22-17-24(10-3-4-11-24)18-23(29)27(22)15-6-5-13-26-14-7-12-25(26)16-20-8-1-2-9-21(20)30-19-25/h1-2,8-9H,3-7,10-19H2
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n/an/a 3.80E+3n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSB


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50054147
PNG
(8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-...)
Show SMILES COc1cccc2OCC3(CCCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C27H38N2O4/c1-32-22-9-8-10-23-21(22)17-27(20-33-23)13-4-5-14-28(27)15-6-7-16-29-24(30)18-26(19-25(29)31)11-2-3-12-26/h8-10H,2-7,11-20H2,1H3
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n/an/a 2.84E+3n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Displacement of [3H]-SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50054155
PNG
(8-{4-[1'-propylspiro[3,4-dihydro-2H-chromene-3,2'-...)
Show SMILES CCCN1CCCC11COc2cccc(OCCCCN3C(=O)CC4(CCCC4)CC3=O)c2C1
Show InChI InChI=1S/C28H40N2O4/c1-2-14-29-15-8-13-28(29)18-22-23(9-7-10-24(22)34-21-28)33-17-6-5-16-30-25(31)19-27(20-26(30)32)11-3-4-12-27/h7,9-10H,2-6,8,11-21H2,1H3
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n/an/a 2.70E+3n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSB


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50054143
PNG
((+) 8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3...)
Show SMILES COc1cccc2OCC3(CCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C26H36N2O4/c1-31-21-8-6-9-22-20(21)16-26(19-32-22)12-7-14-27(26)13-4-5-15-28-23(29)17-25(18-24(28)30)10-2-3-11-25/h6,8-9H,2-5,7,10-19H2,1H3
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n/an/a 6.72n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50054155
PNG
(8-{4-[1'-propylspiro[3,4-dihydro-2H-chromene-3,2'-...)
Show SMILES CCCN1CCCC11COc2cccc(OCCCCN3C(=O)CC4(CCCC4)CC3=O)c2C1
Show InChI InChI=1S/C28H40N2O4/c1-2-14-29-15-8-13-28(29)18-22-23(9-7-10-24(22)34-21-28)33-17-6-5-16-30-25(31)19-27(20-26(30)32)11-3-4-12-27/h7,9-10H,2-6,8,11-21H2,1H3
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n/an/a 101n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50054147
PNG
(8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-...)
Show SMILES COc1cccc2OCC3(CCCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C27H38N2O4/c1-32-22-9-8-10-23-21(22)17-27(20-33-23)13-4-5-14-28(27)15-6-7-16-29-24(30)18-26(19-25(29)31)11-2-3-12-26/h8-10H,2-7,11-20H2,1H3
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n/an/a 8.81n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50054147
PNG
(8-{4-[5-methoxyspiro[3,4-dihydro-2H-chromene-3,2'-...)
Show SMILES COc1cccc2OCC3(CCCCN3CCCCN3C(=O)CC4(CCCC4)CC3=O)Cc12
Show InChI InChI=1S/C27H38N2O4/c1-32-22-9-8-10-23-21(22)17-27(20-33-23)13-4-5-14-28(27)15-6-7-16-29-24(30)18-26(19-25(29)31)11-2-3-12-26/h8-10H,2-7,11-20H2,1H3
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n/an/a 2.21E+3n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSB


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50054154
PNG
(8-[4-spiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydr...)
Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCCC11COc2ccccc2C1
Show InChI InChI=1S/C25H34N2O3/c28-22-17-24(10-3-4-11-24)18-23(29)27(22)15-6-5-13-26-14-7-12-25(26)16-20-8-1-2-9-21(20)30-19-25/h1-2,8-9H,3-7,10-19H2
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n/an/a 178n/an/an/an/an/an/a



Université d'Orléans

Curated by ChEMBL


Assay Description
Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)


J Med Chem 39: 4285-98 (1996)


Article DOI: 10.1021/jm950861w
BindingDB Entry DOI: 10.7270/Q2XP741N
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50036872
PNG
(CHEMBL51985 | [4-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-...)
Show SMILES CCC[N+](C)(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C27H41N2O4/c1-4-15-29(2,21-17-22-23(32-3)10-9-11-24(22)33-20-21)16-8-7-14-28-25(30)18-27(19-26(28)31)12-5-6-13-27/h9-11,21H,4-8,12-20H2,1-3H3/q+1
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n/an/a 1.00E+5n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 in calf striatum


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50036856
PNG
(8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propy...)
Show SMILES CCCN(CCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C25H36N2O4/c1-3-12-26(19-15-20-21(30-2)8-6-9-22(20)31-18-19)13-7-14-27-23(28)16-25(17-24(27)29)10-4-5-11-25/h6,8-9,19H,3-5,7,10-18H2,1-2H3
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n/an/a 8.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036849
PNG
(1-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H36N2O4/c1-5-11-25(18-14-19-20(29-4)9-8-10-21(19)30-17-18)12-6-7-13-26-22(27)15-24(2,3)16-23(26)28/h8-10,18H,5-7,11-17H2,1-4H3
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n/an/a 4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036865
PNG
(8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propo...)
Show SMILES CCCN(CCCON1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C25H36N2O5/c1-3-12-26(19-15-20-21(30-2)8-6-9-22(20)31-18-19)13-7-14-32-27-23(28)16-25(17-24(27)29)10-4-5-11-25/h6,8-9,19H,3-5,7,10-18H2,1-2H3
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n/an/a 1n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 2a (5-HT2a) receptor


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 9.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50036871
PNG
(8-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Show SMILES CCCN(CCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-11-25(18-14-19-20(29-2)7-6-8-21(19)30-17-18)12-13-26-22(27)15-24(16-23(26)28)9-4-5-10-24/h6-8,18H,3-5,9-17H2,1-2H3
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n/an/a>1.00E+6n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036851
PNG
(8-[4-(Chroman-3-yl-propyl-amino)-butyl]-8-aza-spir...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2ccccc2C1
Show InChI InChI=1S/C25H36N2O3/c1-2-13-26(21-16-20-9-3-4-10-22(20)30-19-21)14-7-8-15-27-23(28)17-25(18-24(27)29)11-5-6-12-25/h3-4,9-10,21H,2,5-8,11-19H2,1H3
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n/an/a 2n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50036873
PNG
(8-{5-[(5-Methoxy-chroman-3-yl)-propyl-amino]-penty...)
Show SMILES CCCN(CCCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C27H40N2O4/c1-3-14-28(21-17-22-23(32-2)10-9-11-24(22)33-20-21)15-7-4-8-16-29-25(30)18-27(19-26(29)31)12-5-6-13-27/h9-11,21H,3-8,12-20H2,1-2H3
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n/an/a 6.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against D2 receptor in calf caudate nucleus


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50036870
PNG
(8-[4-(5-Methoxy-chroman-3-ylamino)-butyl]-8-aza-sp...)
Show SMILES COc1cccc2OCC(Cc12)NCCCCN1C(=O)CC2(CCCC2)CC1=O
Show InChI InChI=1S/C23H32N2O4/c1-28-19-7-6-8-20-18(19)13-17(16-29-20)24-11-4-5-12-25-21(26)14-23(15-22(25)27)9-2-3-10-23/h6-8,17,24H,2-5,9-16H2,1H3
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n/an/a 2.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidus


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 5.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 in calf striatum


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50036872
PNG
(CHEMBL51985 | [4-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-...)
Show SMILES CCC[N+](C)(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C27H41N2O4/c1-4-15-29(2,21-17-22-23(32-3)10-9-11-24(22)33-20-21)16-8-7-14-28-25(30)18-27(19-26(28)31)12-5-6-13-27/h9-11,21H,4-8,12-20H2,1-3H3/q+1
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n/an/a 7.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50036850
PNG
(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(O)c2C1
Show InChI InChI=1S/C25H36N2O4/c1-2-12-26(19-15-20-21(28)8-7-9-22(20)31-18-19)13-5-6-14-27-23(29)16-25(17-24(27)30)10-3-4-11-25/h7-9,19,28H,2-6,10-18H2,1H3
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n/an/a 1.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50036849
PNG
(1-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H36N2O4/c1-5-11-25(18-14-19-20(29-4)9-8-10-21(19)30-17-18)12-6-7-13-26-22(27)15-24(2,3)16-23(26)28/h8-10,18H,5-7,11-17H2,1-4H3
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n/an/a 8.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 in calf striatum


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50036855
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1CC2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H36N2O3/c1-3-12-25(19-15-21-22(28-2)10-7-11-23(21)29-17-19)13-4-5-14-26-16-18-8-6-9-20(18)24(26)27/h7,10-11,18-20H,3-6,8-9,12-17H2,1-2H3
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n/an/a 6.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 in calf striatum


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 1n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
adrenergic Alpha2


(BOVINE)
BDBM50036849
PNG
(1-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H36N2O4/c1-5-11-25(18-14-19-20(29-4)9-8-10-21(19)30-17-18)12-6-7-13-26-22(27)15-24(2,3)16-23(26)28/h8-10,18H,5-7,11-17H2,1-4H3
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n/an/a 400n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-2 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD1


(BOVINE)
BDBM50036851
PNG
(8-[4-(Chroman-3-yl-propyl-amino)-butyl]-8-aza-spir...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2ccccc2C1
Show InChI InChI=1S/C25H36N2O3/c1-2-13-26(21-16-20-9-3-4-10-22(20)30-19-21)14-7-8-15-27-23(28)17-25(18-24(27)29)11-5-6-12-25/h3-4,9-10,21H,2,5-8,11-19H2,1H3
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n/an/a 4.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D1 in calf striatum


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor


(CALF)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 8.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-1 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036850
PNG
(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(O)c2C1
Show InChI InChI=1S/C25H36N2O4/c1-2-12-26(19-15-20-21(28)8-7-9-22(20)31-18-19)13-5-6-14-27-23(29)16-25(17-24(27)30)10-3-4-11-25/h7-9,19,28H,2-6,10-18H2,1H3
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n/an/a 1n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 1B/1D receptor


(Rattus norvegicus (Rat))
BDBM50036855
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1CC2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H36N2O3/c1-3-12-25(19-15-21-22(28-2)10-7-11-23(21)29-17-19)13-4-5-14-26-16-18-8-6-9-20(18)24(26)27/h7,10-11,18-20H,3-6,8-9,12-17H2,1-2H3
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n/an/a 3.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidus


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
adrenergic Alpha2


(BOVINE)
BDBM50036856
PNG
(8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propy...)
Show SMILES CCCN(CCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C25H36N2O4/c1-3-12-26(19-15-20-21(30-2)8-6-9-22(20)31-18-19)13-7-14-27-23(28)16-25(17-24(27)29)10-4-5-11-25/h6,8-9,19H,3-5,7,10-18H2,1-2H3
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n/an/a 6.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-2 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 2a (5-HT2a) receptor


(BOVINE)
BDBM50036849
PNG
(1-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H36N2O4/c1-5-11-25(18-14-19-20(29-4)9-8-10-21(19)30-17-18)12-6-7-13-26-22(27)15-24(2,3)16-23(26)28/h8-10,18H,5-7,11-17H2,1-4H3
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n/an/a 6.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 2a (5-HT2a) receptor


(BOVINE)
BDBM50036865
PNG
(8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propo...)
Show SMILES CCCN(CCCON1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C25H36N2O5/c1-3-12-26(19-15-20-21(30-2)8-6-9-22(20)31-18-19)13-7-14-32-27-23(28)16-25(17-24(27)29)10-4-5-11-25/h6,8-9,19H,3-5,7,10-18H2,1-2H3
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n/an/a 4.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
adrenergic Alpha2


(BOVINE)
BDBM50036852
PNG
(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Show SMILES CCCN(CCCCN1C(=O)C2CCCC2C1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-12-25(17-15-20-21(29-2)10-7-11-22(20)30-16-17)13-4-5-14-26-23(27)18-8-6-9-19(18)24(26)28/h7,10-11,17-19H,3-6,8-9,12-16H2,1-2H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against alpha-2 adrenergic receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
DRD2


(BOVINE)
BDBM50036865
PNG
(8-{3-[(5-Methoxy-chroman-3-yl)-propyl-amino]-propo...)
Show SMILES CCCN(CCCON1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C25H36N2O5/c1-3-12-26(19-15-20-21(30-2)8-6-9-22(20)31-18-19)13-7-14-32-27-23(28)16-25(17-24(27)29)10-4-5-11-25/h6,8-9,19H,3-5,7,10-18H2,1-2H3
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n/an/a 20n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against D2 receptor in calf caudate nucleus


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036871
PNG
(8-{2-[(5-Methoxy-chroman-3-yl)-propyl-amino]-ethyl...)
Show SMILES CCCN(CCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1
Show InChI InChI=1S/C24H34N2O4/c1-3-11-25(18-14-19-20(29-2)7-6-8-21(19)30-17-18)12-13-26-22(27)15-24(16-23(26)28)9-4-5-10-24/h6-8,18H,3-5,9-17H2,1-2H3
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n/an/a 30n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranes


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
Serotonin 2a (5-HT2a) receptor


(BOVINE)
BDBM50036870
PNG
(8-[4-(5-Methoxy-chroman-3-ylamino)-butyl]-8-aza-sp...)
Show SMILES COc1cccc2OCC(Cc12)NCCCCN1C(=O)CC2(CCCC2)CC1=O
Show InChI InChI=1S/C23H32N2O4/c1-28-19-7-6-8-20-18(19)13-17(16-29-20)24-11-4-5-12-25-21(26)14-23(15-22(25)27)9-2-3-10-23/h6-8,17,24H,2-5,9-16H2,1H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortex


J Med Chem 37: 1779-93 (1994)


Article DOI: 10.1021/jm00038a007
BindingDB Entry DOI: 10.7270/Q2HH6KPQ
More data for this
Ligand-Target Pair
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